IP3 receptors and their regulation by calmodulin and cytosolic Ca2+.

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IP3 receptors and their regulation by calmodulin and cytosolic Ca2+. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0143416002001859
P698PubMed publication ID12543092

P50authorColin W TaylorQ61472896
P2093author name stringA J Laude
P2860cites workModulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entryQ22010985
Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulinQ22011033
The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and SelectivityQ22337058
ATP-dependent adenophostin activation of inositol 1,4,5-trisphosphate receptor channel gating: kinetic implications for the durations of calcium puffs in cellsQ24644630
Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulinQ27631384
Role of elementary Ca(2+) puffs in generating repetitive Ca(2+) oscillationsQ28354259
Ca(2+)-sensor region of IP(3) receptor controls intracellular Ca(2+) signalingQ28361875
Single-channel properties in endoplasmic reticulum membrane of recombinant type 3 inositol trisphosphate receptorQ28568060
Single-channel function of recombinant type 2 inositol 1,4, 5-trisphosphate receptor.Q28581861
Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptorQ28586214
The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific mannerQ28594256
The versatility and universality of calcium signallingQ29547402
Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptorsQ32064388
Luminal loop of the ryanodine receptor: a pore-forming segment?Q33546213
Inositol 1,4,5-trisphosphate [correction of tris-phosphate] activation of inositol trisphosphate [correction of tris-phosphate] receptor Ca2+ channel by ligand tuning of Ca2+ inhibitionQ33616268
Molecular properties of inositol 1,4,5-trisphosphate receptorsQ33666650
New Ca2+-releasing messengers: are they important in the nervous system?Q33756111
Expression of inositol trisphosphate receptors.Q33834374
Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondriaQ33890261
Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channelsQ34065260
Inositol 1,4,5-trisphosphate 3-kinase A associates with F-actin and dendritic spines via its N terminusQ34084785
Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolutionQ34089878
Isoform-specific function of single inositol 1,4,5-trisphosphate receptor channelsQ34168673
Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphateQ34264314
Light at the end of the Ca(2+)-release channel tunnel: structures and mechanisms involved in ion translocation in ryanodine receptor channelsQ34270683
Highly cooperative opening of calcium channels by inositol 1,4,5-trisphosphateQ34404072
Calmodulin as an ion channel subunitQ34516193
NAADP: an atypical Ca2+-release messenger?Q34586893
Molecular physiology of the SERCA and SPCA pumpsQ35051259
Sphingosine 1-phosphate: a Ca2+ release mediator in the balanceQ35051273
Interactions between calcium release pathways: multiple messengers and multiple stores.Q35051277
Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-trisphosphate receptorsQ35116636
Inositol 1,4,5-Trisphosphate-Activated Calcium ChannelsQ35227047
Biphasic Ca2+ dependence of inositol 1,4,5-trisphosphate-induced Ca release in smooth muscle cells of the guinea pig taenia caeciQ36410573
Regulation of type 1 inositol 1,4,5-trisphosphate-gated calcium channels by InsP3 and calcium: Simulation of single channel kinetics based on ligand binding and electrophysiological analysisQ36427227
The inositol 1,4,5-trisphosphate receptor of cerebellum. Mn2+ permeability and regulation by cytosolic Mn2+Q36435675
Inositol 1,4,5-trisphosphate (InsP3) and calcium interact to increase the dynamic range of InsP3 receptor-dependent calcium signalingQ36435976
Location of the permeation pathway in the recombinant type 1 inositol 1,4,5-trisphosphate receptorQ36438961
Regulation by Ca2+ and inositol 1,4,5-trisphosphate (InsP3) of single recombinant type 3 InsP3 receptor channels. Ca2+ activation uniquely distinguishes types 1 and 3 insp3 receptorsQ36444657
Ca2+-independent inhibition of inositol trisphosphate receptors by calmodulin: redistribution of calmodulin as a possible means of regulating Ca2+ mobilizationQ36604086
Reversible desensitization of inositol trisphosphate-induced calcium release provides a mechanism for repetitive calcium spikesQ36802982
The calmodulin-binding domain in the mouse type 1 inositol 1,4,5-trisphosphate receptorQ38295298
Inositol 1,4,5-trisphosphate receptor down-regulation is activated directly by inositol 1,4,5-trisphosphate binding. Studies with binding-defective mutant receptorsQ38329006
Isolation and characterization of vascular smooth muscle inositol 1,4,5-trisphosphate receptorQ38357764
Molecular and cellular physiology of intracellular calcium storesQ40674713
Determinants of adenophostin A binding to inositol trisphosphate receptorsQ40721734
The high-affinity calcium[bond]calmodulin-binding site does not play a role in the modulation of type 1 inositol 1,4,5-trisphosphate receptor function by calcium and calmodulinQ40736024
Identification of apocalmodulin and Ca2+-calmodulin regulatory domain in skeletal muscle Ca2+ release channel, ryanodine receptorQ40812239
The bell-shaped Ca2+ dependence of the inositol 1,4, 5-trisphosphate-induced Ca2+ release is modulated by Ca2+/calmodulinQ40955406
Type III InsP3 receptor channel stays open in the presence of increased calciumQ40994605
A novel role for calmodulin: Ca2+-independent inhibition of type-1 inositol trisphosphate receptorsQ41013776
Molecular identification of the ryanodine receptor Ca2+ sensorQ41034667
Functional properties of the type-3 InsP3 receptor in 16HBE14o- bronchial mucosal cellsQ41043689
Differential regulation of types-1 and -3 inositol trisphosphate receptors by cytosolic Ca2+Q41067966
Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptorQ41105707
Regulation of inositol 1,4,5-trisphosphate receptors in rat basophilic leukemia cells. I. Multiple conformational states of the receptor in a microsomal preparationQ41560315
Apocalmodulin and Ca2+-calmodulin bind to neighboring locations on the ryanodine receptorQ41630689
Initiation of IP(3)-mediated Ca(2+) waves in Xenopus oocytes.Q41693713
Minimal requirements for calcium oscillations driven by the IP3 receptorQ41831781
Localization and function of a calmodulin-apocalmodulin-binding domain in the N-terminal part of the type 1 inositol 1,4,5-trisphosphate receptor.Q41854278
Ca2+ differentially regulates the ligand-affinity states of type 1 and type 3 inositol 1,4,5-trisphosphate receptorsQ41856637
The effects of free [Ca2+] on the cytosolic face of the inositol (1,4,5)-trisphosphate receptor at the single channel levelQ41991642
Ca2+-calmodulin inhibits Ca2+ release mediated by type-1, -2 and -3 inositol trisphosphate receptors.Q42001681
Characterization of a membrane protein from brain mediating the inhibition of inositol 1,4,5-trisphosphate receptor binding by calciumQ42006380
Encoding of Ca2+ signals by differential expression of IP3 receptor subtypesQ42032529
Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellumQ42150018
Rapid activation and partial inactivation of inositol trisphosphate receptors by inositol trisphosphateQ42460016
Two calcium-binding sites mediate the interconversion of liver inositol 1,4,5-trisphosphate receptors between three conformational states.Q42828218
Micromolar calcium decreases affinity of inositol trisphosphate receptor in vascular smooth muscleQ42834049
Calcium binding to calmodulin leads to an N-terminal shift in its binding site on the ryanodine ReceptorQ43508383
Fast biphasic regulation of type 3 inositol trisphosphate receptors by cytosolic calciumQ43903268
Two-state conformational changes in inositol 1,4,5-trisphosphate receptor regulated by calciumQ43974199
Multiple mechanisms of regulation of the inositol 1,4,5-trisphosphate receptor by calciumQ47778923
Calmodulin mediates calcium-dependent inactivation of the cerebellar type 1 inositol 1,4,5-trisphosphate receptor.Q48115968
Lateral inhibition of inositol 1,4,5-trisphosphate receptors by cytosolic Ca(2+).Q48564741
Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity.Q48568230
Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium releaseQ48738552
ATP regulation of type 1 inositol 1,4,5-trisphosphate receptor channel gating by allosteric tuning of Ca(2+) activationQ48911888
Range of messenger action of calcium ion and inositol 1,4,5-trisphosphateQ49160466
Mechanism of calcium gating in small-conductance calcium-activated potassium channels.Q54432027
Purified inositol 1,4,5-trisphosphate receptor mediates calcium flux in reconstituted lipid vesiclesQ59095132
Inositol 1,4,5-trisphosphate releases Ca2+ from intracellular store sites in skinned single cells of porcine coronary arteryQ71009874
Luminal calcium regulates the inositol trisphosphate receptor of rat basophilic leukemia cells at a cytosolic siteQ71715505
Characterization of a cytosolic and a luminal Ca2+ binding site in the type I inositol 1,4,5-trisphosphate receptorQ71742715
Kinetics of Calcium Release by Immunoaffinity-purified Inositol 1,4,5-Trisphosphate Receptor in Reconstituted Lipid VesiclesQ71977307
Identification and characterization of three calmodulin binding sites of the skeletal muscle ryanodine receptorQ72103003
Calmodulin interaction with the skeletal muscle sarcoplasmic reticulum calcium channel proteinQ72719931
Inositol 1,4,5-trisphosphate and calcium regulate the calcium channel function of the hepatic inositol 1,4,5-trisphosphate receptorQ73009333
The interaction of calmodulin with alternatively spliced isoforms of the type-I inositol trisphosphate receptorQ73377716
Functional properties of recombinant type I and type III inositol 1, 4,5-trisphosphate receptor isoforms expressed in COS-7 cellsQ73675895
Molecular and functional evidence for multiple Ca2+-binding domains in the type 1 inositol 1,4,5-trisphosphate receptorQ73770572
Kinetics of Ca2+ release by InsP3 in pig single aortic endothelial cells: evidence for an inhibitory role of cytosolic Ca2+ in regulating hormonally evoked Ca2+ spikesQ73831497
Two neuropeptides recruit different messenger pathways to evoke Ca2+ signals in the same cellQ74310906
Calmodulin is the Ca2+ sensor for Ca2+ -dependent inactivation of L-type calcium channelsQ77303744
Cooperative formation of the ligand-binding site of the inositol 1,4, 5-trisphosphate receptor by two separable domainsQ77732897
P433issue5-6
P304page(s)321-334
P577publication date2002-11-01
P1433published inCell CalciumQ4340020
P1476titleIP3 receptors and their regulation by calmodulin and cytosolic Ca2+
P478volume32

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