TLR4-MyD88/Mal-NF-kB axis is involved in infection of HSV-2 in human cervical epithelial cells

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TLR4-MyD88/Mal-NF-kB axis is involved in infection of HSV-2 in human cervical epithelial cells is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...880327L
P356DOI10.1371/JOURNAL.PONE.0080327
P8608Fatcat IDrelease_tnwdlbqli5fyxpuuzalcy34uoi
P932PMC publication ID3835891
P698PubMed publication ID24278275
P5875ResearchGate publication ID258924623

P2093author name stringHui Li
Kai Chen
Xinxing Wu
Hongya Liu
Wenqiang Feng
P2860cites workThe myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transductionQ24546498
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.Q45710766
The Role of Toll‐Like Receptors in Herpes Simplex Infection in NeonatesQ57636327
Cutting Edge: Plasmacytoid dendritic cells provide innate immune protection against mucosal viral infection in situQ79370164
HSV-2 induces TLRs and NF-kappaB-dependent cytokines in cervical epithelial cellsQ83148473
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsQ27860900
Pathogen recognition and innate immunityQ27861084
Pattern recognition receptors and inflammationQ27861115
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-betaQ28506630
IRF-7 is the master regulator of type-I interferon-dependent immune responsesQ28511410
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signalingQ28593045
T granules in human platelets function in TLR9 organization and signalingQ30528922
HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytesQ31115332
Requirement for DNA CpG content in TLR9-dependent dendritic cell activation induced by DNA-containing immune complexesQ33815085
The role of HSV in the transmission and progression of HIV.Q34544885
Herpes simplex virus infectionQ34740506
NF-kappaB and virus infection: who controls whomQ35139535
Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cellsQ35768621
Cervical epithelial cells transduced with the papillomavirus E6/E7 oncogenes maintain stable levels of oncoprotein expression but exhibit progressive, major increases in hTERT gene expression and telomerase activityQ35789014
Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitisQ36017935
Herpes simplex virus and toll-like receptorsQ36280405
Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2Q36370493
Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cellsQ36371359
Vaccines for herpes simplex virus infectionsQ36405439
Herpes simplex virus type 2: epidemiology and management options in developing countriesQ36650973
Herpes simplex virus infections of the central nervous system. Encephalitis and neonatal herpesQ36699405
Recognition of herpesviruses by the innate immune systemQ36939781
An update on short-course episodic and prevention therapies for herpes genitalis.Q36945205
Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathwaysQ37388802
MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.Q37433320
Induction of antiviral immunity requires Toll-like receptor signaling in both stromal and dendritic cell compartmentsQ37621719
Innate and adaptive immunity against herpes simplex virus type 2 in the genital mucosa.Q37844936
Activation and regulation of interferon-β in immune responses.Q37992879
Herpes simplex virus type 2 virion host shutoff protein suppresses innate dsRNA antiviral pathways in human vaginal epithelial cellsQ39532187
Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signalingQ40020382
TLR3 deficiency in patients with herpes simplex encephalitisQ40080041
Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathwayQ40172425
Innate immunity at the mucosal surface: role of toll-like receptor 3 and toll-like receptor 9 in cervical epithelial cell responses to microbial pathogensQ40327930
Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signalingQ40615423
Toll-like receptor 4 mediates innate immunity to Kaposi sarcoma herpesvirus.Q41365661
Susceptibility of human female primary genital epithelial cells to herpes simplex virus, type-2 and the effect of TLR3 ligand and sex hormones on infection.Q45256808
Differential induction of innate anti-viral responses by TLR ligands against Herpes simplex virus, type 2, infection in primary genital epithelium of women.Q45388640
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
Human herpesvirus 2Q18965147
P304page(s)e80327
P577publication date2013-11-20
P1433published inPLOS OneQ564954
P1476titleTLR4-MyD88/Mal-NF-kB axis is involved in infection of HSV-2 in human cervical epithelial cells
P478volume8

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cites work (P2860)
Q37716535Ex vivo 2D and 3D HSV-2 infection model using human normal vaginal epithelial cells
Q35145592HSV-2 increases TLR4-dependent phosphorylated IRFs and IFN-β induction in cervical epithelial cells
Q59136245Herpes simplex virus type 2 infection triggers AP-1 transcription activity through TLR4 signaling in genital epithelial cells
Q28546028Human normal bronchial epithelial cells: a novel in vitro cell model for toxicity evaluation
Q36247376Improved Chemotherapeutic Activity by Morus alba Fruits through Immune Response of Toll-Like Receptor 4.
Q41087764Preinduction of heat shock protein 70 protects mice against post-infection irritable bowel syndrome via NF-κB and NOS/NO signaling pathways
Q38802627Transcription Factor NF-κB: An Update on Intervention Strategies

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