Characterization of a polyketide synthase in Aspergillus niger whose product is a precursor for both dihydroxynaphthalene (DHN) melanin and naphtho-γ-pyrone

scientific article

Characterization of a polyketide synthase in Aspergillus niger whose product is a precursor for both dihydroxynaphthalene (DHN) melanin and naphtho-γ-pyrone is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FGB.2010.12.001
P953full work available at URLhttps://europepmc.org/articles/pmc3118676?pdf=render
P932PMC publication ID3118676
P698PubMed publication ID21176790

P7228access restriction statusopen accessQ232932
P50authorYi-Ming ChiangQ42389244
Scott E. BakerQ46104141
Kenneth S BrunoQ61180672
P2093author name stringKristen M Meyer
Clay C C Wang
Michael Praseuth
P2860cites workGenome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88Q21972843
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzaeQ22122464
Identification of a polyketide synthase gene (pksP) of Aspergillus fumigatus involved in conidial pigment biosynthesis and virulence.Q31964789
Chemical induction of silent biosynthetic pathway transcription in Aspergillus niger.Q33466841
A developmentally regulated gene cluster involved in conidial pigment biosynthesis in Aspergillus fumigatus.Q33638317
Fungal secondary metabolism - from biochemistry to genomicsQ34472162
A versatile and efficient gene-targeting system for Aspergillus nidulans.Q34587921
Unlocking fungal cryptic natural products.Q35003959
Unraveling polyketide synthesis in members of the genus AspergillusQ35032980
Aspergillus niger genomics: past, present and into the futureQ36627890
Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secretsQ36854319
A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in Aspergillus nidulansQ37395784
Review of secondary metabolites and mycotoxins from the Aspergillus niger groupQ37597997
Epigenome manipulation as a pathway to new natural product scaffolds and their congenersQ37660083
Chromatin-level regulation of biosynthetic gene clustersQ41371805
Orlandin: a nontoxic fungal metabolite with plant growth inhibiting propertiesQ41631527
Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulansQ42615072
Histone deacetylase activity regulates chemical diversity in AspergillusQ42628294
Pentaketide melanin biosynthesis in Aspergillus fumigatus requires chain-length shortening of a heptaketide precursorQ43606323
Hydrolytic polyketide shortening by ayg1p, a novel enzyme involved in fungal melanin biosynthesisQ45018071
A chemical epigenetics approach for engineering the in situ biosynthesis of a cryptic natural product from Aspergillus niger.Q46155513
Pestalazines and pestalamides, bioactive metabolites from the plant pathogenic fungus Pestalotiopsis theaeQ46316348
Fumonisin B2 production by Aspergillus niger.Q46398778
New dimeric naphthopyrones from Aspergillus niger.Q46945743
Aspergillus fumigatus arp1 modulates conidial pigmentation and complement depositionQ48040851
Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus.Q50714676
Secondary metabolic gene cluster silencing in Aspergillus nidulans.Q53342095
Transient disruption of non-homologous end-joining facilitates targeted genome manipulations in the filamentous fungus Aspergillus nidulansQ61447089
Aspergillus fumigatus alb1 encodes naphthopyrone synthase when expressed in Aspergillus oryzaeQ61522818
Triggering cryptic natural product biosynthesis in microorganismsQ61774190
Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungiQ62090223
Genomic mining for Aspergillus natural productsQ62658783
P433issue4
P921main subjectAspergillus nigerQ132014
aurasperone aQ27274553
aurasperone bQ27275021
fonsecinone bQ27896466
fonsecinone aQ27896467
fonsecinone cQ27896779
Putative polyketide synthase (PKS) involved in both dihydroxynaphthalene (DHN) melanin and naphtho-gamma-pyrone productionQ61556204
Asperpyrone BQ75055149
asperpyrone CQ77494011
NigragillinQ105104530
(2E)-3-phenyl-1-[(2R,5S)-2,4,5-trimethylpiperazin-1-yl]prop-2-en-1-oneQ105164713
P6954online access statusopen accessQ232932
P304page(s)430-437
P577publication date2010-12-19
P1433published inFungal Genetics and BiologyQ5509162
P1476titleCharacterization of a polyketide synthase in Aspergillus niger whose product is a precursor for both dihydroxynaphthalene (DHN) melanin and naphtho-γ-pyrone
P478volume48

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