| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1994PNAS...91.1716G |
| P356 | DOI | 10.1073/PNAS.91.5.1716 |
| P8608 | Fatcat ID | release_vcdlwnmsyzdmlpwzzewdd4pbhu |
| P932 | PMC publication ID | 43234 |
| P698 | PubMed publication ID | 8127870 |
| P5875 | ResearchGate publication ID | 15071123 |
| P2093 | author name string | D J Leahy | |
| J Mennone | |||
| P A Giblin | |||
| P B Kavathas | |||
| P2860 | cites work | The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex | Q24293680 |
| Human growth hormone and extracellular domain of its receptor: crystal structure of the complex | Q24308045 | ||
| Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules | Q24556587 | ||
| Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding | Q28252493 | ||
| SV40-transformed simian cells support the replication of early SV40 mutants | Q28263905 | ||
| Expression of different CD8 isoforms on distinct human lymphocyte subpopulations | Q28270908 | ||
| Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution | Q28287140 | ||
| The immunoglobulin superfamily--domains for cell surface recognition | Q28294978 | ||
| The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck | Q28506433 | ||
| CD8 is needed for development of cytotoxic T cells but not helper T cells | Q28590938 | ||
| SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat | Q29620254 | ||
| Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. | Q34350288 | ||
| Mutations in CD8 that affect interactions with HLA class I and monoclonal anti-CD8 antibodies | Q36230282 | ||
| CD8 is required during positive selection of CD4-/CD8+ T cells | Q36350462 | ||
| Negative regulation of globin gene expression during megakaryocytic differentiation of a human erythroleukemic cell line | Q36724771 | ||
| Human immunodeficiency virus gp120 binding C'C" ridge of CD4 domain 1 is also involved in interaction with class II major histocompatibility complex molecules | Q37347544 | ||
| Synergism in the activation of human CD8 T cells by cross-linking the T-cell receptor complex with the CD8 differentiation antigen | Q37406056 | ||
| Binding of thymic factors to the conserved decanucleotide promoter element of the T-cell receptor V beta gene is developmentally regulated and is absent in SCID mice | Q37594674 | ||
| UC 729-6, a human lymphoblastoid B-cell line useful for generating antibody-secreting human-human hybridomas | Q37618105 | ||
| Recognition by CD8 on cytotoxic T lymphocytes is ablated by several substitutions in the class I alpha 3 domain: CD8 and the T-cell receptor recognize the same class I molecule | Q37718898 | ||
| Functional importance of the cyclic AMP response element-like decamer motif in the CD8 alpha promoter | Q38319251 | ||
| Structure of antibody-antigen complexes: implications for immune recognition. | Q39539191 | ||
| Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8. | Q41324928 | ||
| CD4 and CD8 are positive regulators of T cell receptor signal transduction in early T cell differentiation | Q41691256 | ||
| A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2. | Q41734593 | ||
| Differential expression and regulation of the human CD8 alpha and CD8 beta chains | Q41746466 | ||
| Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8. | Q43745715 | ||
| Co-engagement of CD8 with the T cell receptor is required for negative selection | Q43972483 | ||
| Structural aspects of CD4 and CD8 involvement in the cellular immune response | Q44026266 | ||
| Substitution at residue 227 of H-2 class I molecules abrogates recognition by CD8-dependent, but not CD8-independent, cytotoxic T lymphocytes | Q44026639 | ||
| Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the alpha 3 domain of MHC I molecules | Q44276459 | ||
| Engagement of class I major histocompatibility complex molecules by cell surface CD8 delivers an activation signal | Q46251590 | ||
| Transfection of the CD8 gene enhances T-cell recognition. | Q53939368 | ||
| Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes | Q57275641 | ||
| Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site | Q67969096 | ||
| Comparative analysis of CD8 expressed on mature CD4+ CD8+ T cell clones cultured with IL-4 and that on CD8+ T cell clones: implication for functional significance of CD8 beta | Q68000279 | ||
| The MHC-binding and gp120-binding functions of CD4 are separable | Q69355384 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1716-1720 | |
| P577 | publication date | 1994-03-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | The role of charge and multiple faces of the CD8 alpha/alpha homodimer in binding to major histocompatibility complex class I molecules: support for a bivalent model | |
| P478 | volume | 91 |
| Q74310276 | A structure-based approach to designing synthetic CD8alpha peptides that can inhibit cytotoxic T-lymphocyte responses |
| Q42065609 | Assembly and crystallization of the complex between the human T cell coreceptor CD8alpha homodimer and HLA-A2. |
| Q34719707 | Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4). A disulfide-linked homodimer binds two CD86 molecules |
| Q24323038 | Characterization of the major histocompatibility complex class II binding site on LAG-3 protein |
| Q41417560 | Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1. |
| Q27738835 | Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2 |
| Q42411852 | Crystallization and preliminary X-ray structural studies of a high-affinity CD8alphaalpha co-receptor to pMHC |
| Q41991755 | Glu227-->Lys substitution in the acidic loop of major histocompatibility complex class I alpha 3 domain distinguishes low avidity CD8 coreceptor and avidity-enhanced CD8 accessory functions |
| Q36365522 | Human CD8 transgene regulation of HLA recognition by murine T cells |
| Q47954431 | Identification of the CD8 DE loop as a surface functional epitope. Implications for major histocompatibility complex class I binding and CD8 inhibitor design |
| Q41753464 | Immunoglobulin superfamily proteins: structure, mechanisms, and drug discovery |
| Q36365379 | Interaction between CD8 and major histocompatibility complex (MHC) class I mediated by multiple contact surfaces that include the alpha 2 and alpha 3 domains of MHC class I |
| Q34493030 | Interactions between MHC molecules and co-receptors of the TCR. |
| Q33736030 | Molecular analysis of protein interactions mediating the function of the cell surface protein CD8. |
| Q33927920 | Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor |
| Q41605278 | Peptide binding by class I and class II MHC molecules |
| Q35824436 | Production and characterization of transformed B-lymphocytes expressing the membrane defect of Scott syndrome |
| Q33183985 | Sequence conservation in the chagasin family suggests a common trend in cysteine proteinase binding by unrelated protein inhibitors |
| Q78126158 | Soluble CD8 stabilizes the HLA class I molecule by promoting beta2M exchange: analysis in real-time |
| Q27765904 | Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb |
| Q74595059 | T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics |
| Q33878809 | The MHC class II ligand lymphocyte activation gene-3 is co-distributed with CD8 and CD3-TCR molecules after their engagement by mAb or peptide-MHC class I complexes |
| Q43772835 | The marsupial CD8 gene locus: molecular cloning and expression analysis of the alpha and beta sequences in the gray short-tailed opossum (Monodelphis domestica) and the tammar wallaby (Macropus eugenii). |
| Q24563048 | The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain |
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