Recombinant influenza virus expressing a fusion protein neutralizing epitope of respiratory syncytial virus (RSV) confers protection without vaccine-enhanced RSV disease

scientific article

Recombinant influenza virus expressing a fusion protein neutralizing epitope of respiratory syncytial virus (RSV) confers protection without vaccine-enhanced RSV disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.ANTIVIRAL.2014.12.009
P932PMC publication ID4323669
P698PubMed publication ID25513755
P5875ResearchGate publication ID269774264

P2093author name stringSang-Moo Kang
Jong Seok Lee
Hye Suk Hwang
Min-Chul Kim
Yu-Na Lee
Young-Tae Lee
Martin L Moore
P2860cites workRespiratory syncytial virus induces pneumonia, cytokine response, airway obstruction, and chronic inflammatory infiltrates associated with long-term airway hyperresponsiveness in miceQ44880088
Non-propagating, recombinant vesicular stomatitis virus vectors encoding respiratory syncytial virus proteins generate potent humoral and cellular immunity against RSV and are protective in miceQ45353370
The interferon antagonist NS2 protein of respiratory syncytial virus is an important virulence determinant for humansQ45420643
Motavizumab for prophylaxis of respiratory syncytial virus in high-risk children: a noninferiority trialQ45458064
Identification of a recombinant live attenuated respiratory syncytial virus vaccine candidate that is highly attenuated in infantsQ45504141
Bovine parainfluenza virus type 3 (PIV3) expressing the respiratory syncytial virus (RSV) attachment and fusion proteins protects hamsters from challenge with human PIV3 and RSV.Q45722558
Vaccine-enhanced respiratory syncytial virus disease in cotton rats following immunization with Lot 100 or a newly prepared reference vaccineQ45734744
Priming and boosting immunity to respiratory syncytial virus by recombinant replication-defective vaccinia virus MVA.Q45746795
Purified fusion protein vaccine protects against lower respiratory tract illness during respiratory syncytial virus season in children with cystic fibrosisQ45769900
A comparison in chimpanzees of the immunogenicity and efficacy of live attenuated respiratory syncytial virus (RSV) temperature-sensitive mutant vaccines and vaccinia virus recombinants that express the surface glycoproteins of RSV.Q45776569
Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunizationQ45849864
Comparison of the ability of formalin-inactivated respiratory syncytial virus, immunopurified F, G and N proteins and cell lysate to enhance pulmonary changes in Balb/c miceQ45868048
Immunogenicity of recombinant adenovirus-respiratory syncytial virus vaccines with adenovirus types 4, 5, and 7 vectors in dogs and a chimpanzeeQ45868590
Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. The IMpact-RSV Study GroupQ77300551
Detection and quantitation of eosinophils in the murine respiratory tract by flow cytometryQ24657793
Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing EpitopesQ27668015
Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysisQ29619821
A DNA transfection system for generation of influenza A virus from eight plasmidsQ29642855
Characterization of two antigenic sites recognized by neutralizing monoclonal antibodies directed against the fusion glycoprotein of human respiratory syncytial virusQ30334543
Immune responses to influenza virus infectionQ30407654
Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virusQ30441455
Chimeric influenza virus hemagglutinin proteins containing large domains of the Bacillus anthracis protective antigen: protein characterization, incorporation into infectious influenza viruses, and antigenicityQ33908690
Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccineQ34206177
The respiratory syncytial virus G protein conserved domain induces a persistent and protective antibody response in rodentsQ34222406
Respiratory syncytial virus infection in elderly and high-risk adultsQ34414401
Respiratory syncytial virus fusion glycoprotein expressed in insect cells form protein nanoparticles that induce protective immunity in cotton ratsQ34506016
Influenza virus: immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccinesQ35629114
Antibody response to the central unglycosylated region of the respiratory syncytial virus attachment protein in miceQ36106575
Long-term and memory immune responses in mice against Newcastle disease virus-like particles containing respiratory syncytial virus glycoprotein ectodomainsQ36363325
An adjuvanted respiratory syncytial virus fusion protein induces protection in aged BALB/c miceQ36500189
Recombinant influenza virus carrying the respiratory syncytial virus (RSV) F85-93 CTL epitope reduces RSV replication in miceQ36667922
Overcoming T cell-mediated immunopathology to achieve safe RSV vaccination.Q36993991
Comparison of histochemical methods for murine eosinophil detection in an RSV vaccine-enhanced inflammation model.Q37147650
Expression of the F glycoprotein of respiratory syncytial virus by a recombinant vaccinia virus: comparison of the individual contributions of the F and G glycoproteins to host immunityQ37401975
Intranasal immunization with inactivated influenza virus enhances immune responses to coadministered simian-human immunodeficiency virus-like particle antigens.Q37492531
A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology.Q37627348
Maternal antibodies by passive immunization with formalin inactivated respiratory syncytial virus confer protection without vaccine-enhanced diseaseQ37649439
Genetic vaccine for respiratory syncytial virus provides protection without disease potentiationQ37690464
Chimeric bovine/human parainfluenza virus type 3 expressing respiratory syncytial virus (RSV) F glycoprotein: effect of insert position on expression, replication, immunogenicity, stability, and protection against RSV infection.Q37713874
Development of an adenovirus-based respiratory syncytial virus vaccine: preclinical evaluation of efficacy, immunogenicity, and enhanced disease in a cotton rat modelQ37713960
Influenza virus vaccine expressing fusion and attachment protein epitopes of respiratory syncytial virus induces protective antibodies in BALB/c miceQ39025841
Respiratory syncytial virus-neutralizing monoclonal antibodies motavizumab and palivizumab inhibit fusionQ39697277
Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tractQ40158643
A further attenuated derivative of a cold-passaged temperature-sensitive mutant of human respiratory syncytial virus retains immunogenicity and protective efficacy against wild-type challenge in seronegative chimpanzeesQ41458369
Retroviral display of functional binding domains fused to the amino terminus of influenza hemagglutinin.Q41482419
Vaccination with the RSV fusion protein formulated with a combination adjuvant induces long-lasting protective immunity.Q42235080
P304page(s)1-8
P577publication date2014-12-13
P1433published inAntiviral ResearchQ4775352
P1476titleRecombinant influenza virus expressing a fusion protein neutralizing epitope of respiratory syncytial virus (RSV) confers protection without vaccine-enhanced RSV disease
P478volume115

Reverse relations

cites work (P2860)
Q38905050A Single-Dose Recombinant Parainfluenza Virus 5-Vectored Vaccine Expressing Respiratory Syncytial Virus (RSV) F or G Protein Protected Cotton Rats and African Green Monkeys from RSV Challenge
Q40664205Cold-adapted influenza viruses as a promising platform for viral-vector vaccines.
Q90168333Identification of a human respiratory syncytial virus phosphoprotein domain required for virus-like-particle formation
Q38830323Multivalent and Multipathogen Viral Vector Vaccines
Q36739674Protection against respiratory syncytial virus by inactivated influenza virus carrying a fusion protein neutralizing epitope in a chimeric hemagglutinin
Q37189330Responses of primary human nasal epithelial cells to EDIII-DENV stimulation: the first step to intranasal dengue vaccination
Q104756334Tetramerization of Phosphoprotein is Essential for Respiratory Syncytial Virus Budding while its N Terminal Region Mediates Direct Interactions with the Matrix Protein
Q116166800Tetramerization of Phosphoprotein is essential for Respiratory Syncytial virus budding while its N terminal region mediates direct interactions with the Matrix protein

Search more.