Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1.

scientific article

Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1. is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2013PLoSO...882666Q
P356DOI10.1371/JOURNAL.PONE.0082666
P932PMC publication ID3857783
P698PubMed publication ID24349332
P5875ResearchGate publication ID259355217

P50authorYanbin ZhangQ44027005
P2093author name stringFenghua Yuan
Liangyue Qian
Suyog Padgaonkar
Paola Rodriguez-Tello
P2860cites workFanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complexQ24291944
Human MUS81 complexes stimulate flap endonuclease 1Q24318451
Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitroQ24319018
The characterization of a mammalian DNA structure-specific endonucleaseQ24336672
Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replicationQ24560006
Molecular pathogenesis and clinical management of Fanconi anemiaQ24621696
Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded formsQ24631719
Okazaki fragment maturation: nucleases take centre stageQ24632622
A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom SyndromeQ24669612
Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear AntigenQ27931829
Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repairQ28198657
Heterogeneous activation of the Fanconi anemia pathway by patient-derived FANCA mutantsQ28215517
Flap endonuclease 1: a central component of DNA metabolismQ28266199
Aberrant activation of stress-response pathways leads to TNF-alpha oversecretion in Fanconi anemiaQ80138278
Biochemical characterization of the WRN-FEN-1 functional interactionQ44160517
Is Fanconi's anaemia defective in a process essential to the repair of DNA cross links?Q44775164
Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiaeQ46062549
Fen1 mutations result in autoimmunity, chronic inflammation and cancersQ46593630
Processing of a psoralen DNA interstrand cross-link by XPF-ERCC1 complex in vitroQ46897838
Involvement of flap endonuclease 1 in base excision DNA repair.Q48038198
Spectrum of sequence variations in the FANCA gene: an International Fanconi Anemia Registry (IFAR) study.Q52060614
The Fanconi anemia pathway of genomic maintenance.Q53624384
Identification of the Fanconi anemia complementation group I gene, FANCI.Q54858556
Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision RepairQ57706957
Role of calf RTH-1 nuclease in removal of 5'-ribonucleotides during Okazaki fragment processingQ71248763
Human RAD2 homolog 1 5'- to 3'-exo/endonuclease can efficiently excise a displaced DNA fragment containing a 5'-terminal abasic lesion by endonuclease activityQ71825123
The calf 5'- to 3'-exonuclease is also an endonuclease with both activities dependent on primers annealed upstream of the point of cleavageQ72724960
Fanconi anaemia and the repair of Watson and Crick DNA crosslinksQ28283549
Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemiaQ28289720
Distinct roles of two Mg2+ binding sites in regulation of murine flap endonuclease-1 activitiesQ28511149
Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1Q28645598
Fanconi anemia proteins localize to chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated mannerQ30307206
RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotesQ30704734
Fanconi anemia proteins stabilize replication forksQ33368942
Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progressionQ34098053
Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forksQ34166526
Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaksQ34301932
The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.Q34499459
Functional regulation of FEN1 nuclease and its link to cancerQ34559690
A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing eventsQ34988376
Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein.Q35028557
CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradationQ35160522
The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutantsQ35167583
Enzymatic completion of mammalian lagging-strand DNA replicationQ35814024
Identification and characterization of OGG1 mutations in patients with Alzheimer's diseaseQ35829350
How Fanconi anemia proteins promote the four Rs: replication, recombination, repair, and recoveryQ36019436
Fanconi anemia (cross)linked to DNA repairQ36353502
Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4.Q36512615
Fanconi anaemia genes and susceptibility to cancerQ36602573
Fanconi anemia and DNA replication repairQ36811854
Flap endonuclease 1.Q36920133
Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteinsQ36927976
The genetic and molecular basis of Fanconi anemiaQ37343126
Fanconi anemia and its diagnosisQ37344270
The Fanconi anemia pathway promotes DNA glycosylase-dependent excision of interstrand DNA crosslinksQ37684917
Assembling an orchestra: Fanconi anemia pathway of DNA repairQ37761980
TNF-α signaling in Fanconi anemiaQ38124483
Calf RTH-1 nuclease can remove the initiator RNAs of Okazaki fragments by endonuclease activityQ38352178
Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA.Q39716441
TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitro.Q40647455
FEN1 stimulation of DNA polymerase beta mediates an excision step in mammalian long patch base excision repair.Q40901912
Human replication factor C stimulates flap endonuclease 1Q41809029
Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA.Q42642935
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectFanconi anemia complementation group AQ32147067
P304page(s)e82666
P577publication date2013-12-04
P1433published inPLOS OneQ564954
P1476titleHuman Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1.
P478volume8

Reverse relations

cites work (P2860)
Q38669183BERing the burden of damage: Pathway crosstalk and posttranslational modification of base excision repair proteins regulate DNA damage management
Q64389157FANCA Promotes DNA Double-Strand Break Repair by Catalyzing Single-Strand Annealing and Strand Exchange
Q42371486Lysine methylation of FEN1 by SET7 is essential for its cellular response to replicative stress
Q37658498Maintenance of genome stability by Fanconi anemia proteins
Q50113616Missed cleavage opportunities by FEN1 lead to Okazaki fragment maturation via the long-flap pathway.
Q34158710Polymorphism of the flap endonuclease 1 gene in keratoconus and Fuchs endothelial corneal dystrophy.
Q37429271Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder
Q36409202Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes.
Q39897828p53 downregulates the Fanconi anaemia DNA repair pathway.

Search more.