| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1021839006 |
| P356 | DOI | 10.2165/00003495-200363050-00001 |
| P698 | PubMed publication ID | 12600224 |
| P2093 | author name string | Steven M Pogwizd | |
| P2860 | cites work | Mechanisms underlying spontaneous and induced ventricular arrhythmias in patients with idiopathic dilated cardiomyopathy | Q77614544 |
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| Characterization of a [Ca2+]i-dependent current in human atrial and ventricular cardiomyocytes in the absence of Na+ and K+ | Q77746025 | ||
| Cardioprotective effects of KB-R7943: a novel inhibitor of the reverse mode of Na+/Ca2+ exchanger | Q77855462 | ||
| Intracellular sodium accumulation during ischemia as the substrate for reperfusion injury | Q77921816 | ||
| Cardiac Na/Ca exchange function in rabbit, mouse and man: what's the difference? | Q78049992 | ||
| Sodium/calcium exchange contributes to contraction and relaxation in failed human ventricular myocytes | Q78117508 | ||
| Na/Ca exchange in heart failure: contractile dysfunction and arrhythmogenesis | Q78719599 | ||
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| Cardiac Na(+)-Ca(2+) exchange: molecular and pharmacological aspects | Q34248999 | ||
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| Effects of exogenous free radicals on electromechanical function and metabolism in isolated rabbit and guinea pig ventricle. Implications for ischemia and reperfusion injury | Q34574070 | ||
| Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy? | Q34581523 | ||
| Direction-independent block of bi-directional Na+/Ca2+ exchange current by KB-R7943 in guinea-pig cardiac myocytes | Q35041652 | ||
| A novel antagonist, No. 7943, of the Na+/Ca2+ exchange current in guinea-pig cardiac ventricular cells | Q35884468 | ||
| Inhibition of Na+/Ca2+ exchange in membrane vesicle and papillary muscle preparations from guinea pig heart by analogs of amiloride | Q36261914 | ||
| Gene expression of the cardiac Na(+)-Ca2+ exchanger in end-stage human heart failure | Q36737403 | ||
| Inhibitors of sodium-calcium exchange: identification and development of probes of transport activity | Q38630170 | ||
| Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction | Q38701805 | ||
| Recent insights pertaining to sarcolemmal phospholipid alterations underlying arrhythmogenesis in the ischemic heart. | Q40795013 | ||
| Study of the mechanisms of hydrogen peroxide and hydroxyl free radical-induced cellular injury and calcium overload in cardiac myocytes | Q41154617 | ||
| Amiloride delays the ischemia-induced rise in cytosolic free calcium | Q41162559 | ||
| Membrane electrical properties of vesicular Na-Ca exchange inhibitors in single atrial myocytes | Q41247885 | ||
| Reentrant and nonreentrant mechanisms contribute to arrhythmogenesis during early myocardial ischemia: results using three-dimensional mapping | Q69206490 | ||
| Sudden unexpected death in patients with congestive heart failure: a second frontier | Q69868042 | ||
| Possible mechanisms of ventricular arrhythmias elicited by ischemia followed by reperfusion. Studies on isolated canine ventricular tissues | Q70058438 | ||
| Effects of fatty acids on Na+-Ca2+ exchange and Ca2+ permeability of cardiac sarcolemmal vesicles | Q70093119 | ||
| Inhibition and activation of Na+-Ca2+ exchange activity by quinacrine | Q70326263 | ||
| Ca2+ influx during the cardiac action potential in guinea pig ventricular myocytes | Q71393633 | ||
| A novel isothiourea derivative selectively inhibits the reverse mode of Na+/Ca2+ exchange in cells expressing NCX1 | Q71514602 | ||
| Non-selective effects of amiloride and its analogues on ion transport systems and their cytotoxicities in cardiac myocytes | Q71517246 | ||
| Nonreentrant mechanisms underlying spontaneous ventricular arrhythmias in a model of nonischemic heart failure in rabbits | Q71705759 | ||
| Triggered activity and automaticity in ventricular trabeculae of failing human and rabbit hearts | Q71987897 | ||
| Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms | Q72096800 | ||
| Contribution of Na(+)-Ca2+ exchange to stimulation of transient inward current by isoproterenol in rabbit cardiac Purkinje fibers | Q72642183 | ||
| Dephosphorylation and intracellular redistribution of ventricular connexin43 during electrical uncoupling induced by ischemia | Q73071883 | ||
| Enhanced Ca(2+)-activated Na(+)-Ca(2+) exchange activity in canine pacing-induced heart failure | Q73071898 | ||
| Role of Na(+)/H(+) exchanger during ischemia and preconditioning in the isolated rat heart | Q73082829 | ||
| Enhanced Ca(2+) release and Na/Ca exchange activity in hypertrophied canine ventricular myocytes: potential link between contractile adaptation and arrhythmogenesis | Q73108727 | ||
| Contribution of the Na(+) channel and Na(+)/H(+) exchanger to the anoxic rise of [Na(+)] in ventricular myocytes | Q73188719 | ||
| Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure | Q73204498 | ||
| Influence of a Na+-H+ exchange inhibitor ethylisopropylamiloride, a Na+-Ca2+ exchange inhibitor KB-R7943 and their combination on the increases in contractility and Ca2+ transient induced by angiotensin II in isolated adult rabbit ventricular myocyt | Q73274268 | ||
| KB-R7943 block of Ca(2+) influx via Na(+)/Ca(2+) exchange does not alter twitches or glycoside inotropy but prevents Ca(2+) overload in rat ventricular myocytes | Q73590745 | ||
| [Effects of KB-R7943, a novel Na+/Ca2+ exchange inhibitor, on myocardial ischemia/reperfusion injury] | Q74478349 | ||
| The sarcoplasmic reticulum and the Na+/Ca2+ exchanger both contribute to the Ca2+ transient of failing human ventricular myocytes | Q74583485 | ||
| The sodium-calcium ion membrane exchanger: physiologic significance and pharmacologic implications | Q74592724 | ||
| Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies | Q74615260 | ||
| LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport | Q77136323 | ||
| Effect of amiloride on ischaemia and reperfusion injury in isolated, perfused rat hearts | Q77385133 | ||
| Effect of SEA0400, a novel inhibitor of sodium-calcium exchanger, on myocardial ionic currents | Q41877028 | ||
| Na(+)-Ca(2+) exchange current and submembrane [Ca(2+)] during the cardiac action potential | Q42162128 | ||
| Role of cardiac ATP-regulated potassium channels in differential responses of endocardial and epicardial cells to ischemia | Q42628313 | ||
| Role of Na+/Ca2+ exchange in endothelin-1-induced increases in Ca2+ transient and contractility in rabbit ventricular myocytes: pharmacological analysis with KB-R7943. | Q43191105 | ||
| Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness | Q43633756 | ||
| SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models. | Q43641903 | ||
| Inhibition of Na+/Ca2+ exchange by KB-R7943: transport mode selectivity and antiarrhythmic consequences | Q43713929 | ||
| Reperfusion-induced Ins(1,4,5)P(3) generation and arrhythmogenesis require activation of the Na(+)/Ca(2+) exchanger | Q43768613 | ||
| Amiloride derivatives are potent blockers of KATP channels | Q43782102 | ||
| Very low dose of the Na(+)/Ca(2+) exchange inhibitor, KB-R7943, protects ischemic reperfused aged Fischer 344 rat hearts: considerable strain difference in the sensitivity to KB-R7943. | Q43818592 | ||
| Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged | Q44009242 | ||
| Knockout mice for pharmacological screening: testing the specificity of Na+-Ca2+ exchange inhibitors | Q44079665 | ||
| Changes in extracellular and intracellular pH in ischemic rabbit papillary muscle | Q44523577 | ||
| Membrane potential fluctuations and transient inward currents induced by reactive oxygen intermediates in isolated rabbit ventricular cells | Q44644103 | ||
| Stoichiometry of Na+-Ca2+ exchange in inside-out patches excised from guinea-pig ventricular myocytes | Q46150598 | ||
| Free radicals enhance Na+/Ca2+ exchange in ventricular myocytes | Q46164775 | ||
| Effects of amiloride and an analogue on ventricular arrhythmias, contracture and cellular injury during reperfusion in isolated and perfused guinea pig heart | Q46181071 | ||
| Amiloride derivatives as blockers of Na+/Ca2+ exchange: effects on mechanical and electrical function of guinea-pig myocardium | Q46199418 | ||
| Effect of intracellular and extracellular pH on contraction in isolated, mammalian cardiac muscle | Q46300857 | ||
| The effect of exchanger inhibitory peptide (XIP) on sodium-calcium exchange current in guinea pig ventricular cells | Q46362503 | ||
| Low efficiency of Ca2+ entry through the Na(+)-Ca2+ exchanger as trigger for Ca2+ release from the sarcoplasmic reticulum. A comparison between L-type Ca2+ current and reverse-mode Na(+)-Ca2+ exchange | Q46368147 | ||
| A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes | Q46410988 | ||
| Effects of components of ischemia and metabolic inhibition on delayed afterdepolarizations in guinea pig papillary muscle | Q46428153 | ||
| Effects of a selective inhibitor of Na+/Ca2+ exchange, KB-R7943, on reoxygenation-induced injuries in guinea pig papillary muscles | Q46623202 | ||
| Can Ca entry via Na-Ca exchange directly activate cardiac muscle contraction? | Q46675235 | ||
| Voltage dependence of sodium-calcium exchange current in guinea-pig atrial myocytes determined by means of an inhibitor | Q46858324 | ||
| The role of L-type Ca2+ current and Na+ current-stimulated Na/Ca exchange in triggering SR calcium release in guinea-pig cardiac ventricular myocytes | Q46915476 | ||
| Simulation study of cellular electric properties in heart failure | Q47951135 | ||
| Contribution of reverse-mode sodium-calcium exchange to contractions in failing human left ventricular myocytes | Q48008656 | ||
| Human myocardial Na,K-ATPase--quantification, regulation and relation to Ca. | Q48008705 | ||
| Alterations of calcium-regulatory proteins in heart failure | Q48008757 | ||
| Relationship between Na+-Ca2+-exchanger protein levels and diastolic function of failing human myocardium | Q48749719 | ||
| A Na+/Ca2+ exchanger inhibitor, KB-R7943, caused negative inotropic responses and negative followed by positive chronotropic responses in isolated, blood-perfused dog heart preparations. | Q51393218 | ||
| Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx. | Q51475181 | ||
| Hypoxia increases persistent sodium current in rat ventricular myocytes. | Q51556510 | ||
| Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine | Q51681107 | ||
| Modelling myocardial ischaemia and reperfusion. | Q52233626 | ||
| The stoichiometry of the cardiac sodium-calcium exchange system. | Q52692477 | ||
| Effects of N-chlorobenzyl analogues of amiloride on myocardial contractility, Na-Ca-exchange carrier and other cardiac enzymatic activities. | Q53872792 | ||
| Inhibition of sodium-calcium exchange in cardiac sarcolemmal membrane vesicles. 1. Mechanism of inhibition by amiloride analogues. | Q54169921 | ||
| Electrical uncoupling and increase of extracellular resistance after induction of ischemia in isolated, arterially perfused rabbit papillary muscle. | Q54402233 | ||
| Quantification of [Ca2+]i in perfused hearts. Critical evaluation of the 5F-BAPTA and nuclear magnetic resonance method as applied to the study of ischemia and reperfusion | Q67288647 | ||
| Amiloride in ouabain-induced acidification, inotropy and arrhythmia: 23Na & 31P NMR in perfused hearts | Q67491676 | ||
| Reentrant and focal mechanisms underlying ventricular tachycardia in the human heart | Q67593293 | ||
| Amiloride. Antiarrhythmic and electrophysiological activity in the dog | Q67969213 | ||
| Abnormal electrical activity induced by free radical generating systems in isolated cardiocytes | Q68074350 | ||
| Inhibition of sodium-calcium exchange in cardiac sarcolemmal membrane vesicles. 2. Mechanism of inhibition by bepridil | Q68094847 | ||
| Identification of a peptide inhibitor of the cardiac sarcolemmal Na(+)-Ca2+ exchanger | Q68179687 | ||
| Mechanisms underlying the development of ventricular fibrillation during early myocardial ischemia | Q68715368 | ||
| Mechanisms of reoxygenation-induced calcium overload in cultured chick embryo heart cells | Q69029742 | ||
| Electrophysiologic mechanisms underlying arrhythmias due to reperfusion of ischemic myocardium | Q69122916 | ||
| P433 | issue | 5 | |
| P304 | page(s) | 439-452 | |
| P577 | publication date | 2003-01-01 | |
| P1433 | published in | Drugs | Q3040094 |
| P1476 | title | Clinical potential of sodium-calcium exchanger inhibitors as antiarrhythmic agents | |
| P478 | volume | 63 |
| Q54581273 | A molecular formula for heart failure and sudden cardiac death. Focus on "Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice". |
| Q59000623 | Differences in Expression and Function in the Atrium versus Ventricle of the Sodium-Calcium Exchanger in the Embryonic Chicken Heart |
| Q40313784 | Establishment of cell-free electrophysiology for ion transporters: application for pharmacological profiling |
| Q36132294 | Ion channels as novel therapeutic targets in heart failure |
| Q35164744 | Is timing everything? Therapeutic potential of modulators of cardiac Na(+) transporters |
| Q37101211 | Mechanisms of disease: ion channel remodeling in the failing ventricle |
| Q28258875 | Na+/Ca2+ exchange and Na+/K+-ATPase in the heart |
| Q37237158 | ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart |
| Q35048417 | Selective inhibition of sodium-calcium exchanger by SEA-0400 decreases early and delayed after depolarization in canine heart |
| Q45032152 | Sodium channels are required during in vivo sodium chloride hyperosmolarity to stimulate increase in intestinal endothelial nitric oxide production |
| Q40571326 | The endogenous inhibitor of NCX1 does not resemble the properties of digitalis compound. |
| Q46476410 | The investigation of the cellular electrophysiological and antiarrhythmic effects of a novel selective sodium-calcium exchanger inhibitor, GYKB-6635, in canine and guinea-pig hearts |
| Q35790795 | The potential of Na+/Ca2+ exchange blockers in the treatment of cardiac disease |
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