Functional RNAi screen targeting cytokine and growth factor receptors reveals oncorequisite role for interleukin-2 gamma receptor in JAK3-mutation-positive leukemia.

scientific article

Functional RNAi screen targeting cytokine and growth factor receptors reveals oncorequisite role for interleukin-2 gamma receptor in JAK3-mutation-positive leukemia. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/ONC.2014.243
P932PMC publication ID4324389
P698PubMed publication ID25109334
P5875ResearchGate publication ID264628776

P50authorBrian DrukerQ373427
Kevin Watanabe-SmithQ42544817
Monika A DavareQ64503291
P2093author name stringA Agarwal
R M Braziel
B Park
C A Eide
J W Tyner
S Mongoue-Tchokote
C E Tognon
R J MacKenzie
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Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukaemia accompanying Down syndromeQ39993986
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Critical sites for the interaction between IL-2Rgamma and JAK3 and the following signalingQ40807661
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Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancersQ45344494
T cell development and activation in Jak3-deficient miceQ47992367
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia.Q53307880
Recurrent JAK1 and JAK3 somatic mutations in T-cell prolymphocytic leukemia.Q54408212
Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia.Q54522930
JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adultsQ79657116
Loss-of-function JAK3 mutations in TMD and AMKL of Down syndromeQ80209094
Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemiaQ84019010
P433issue23
P407language of work or nameEnglishQ1860
P304page(s)2991-2999
P577publication date2014-08-11
P1433published inOncogeneQ1568657
P1476titleFunctional RNAi screen targeting cytokine and growth factor receptors reveals oncorequisite role for interleukin-2 gamma receptor in JAK3-mutation-positive leukemia
P478volume34