Toll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury.

scientific article

Toll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/BRAIN/AWT341
P698PubMed publication ID24369381
P5875ResearchGate publication ID259467985

P50authorManoj Kumar MishraQ42968855
V. Wee YongQ56101901
P2093author name stringDavid P Stirling
Karen Cummins
Peter Stys
Wulin Teo
P2860cites workResting microglial cells are highly dynamic surveillants of brain parenchyma in vivoQ27860578
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsQ27860900
Alternative activation of macrophagesQ27860939
Dectin-1 mediates the biological effects of beta-glucansQ28509437
Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFPQ29547505
Macrophage plasticity and polarization: in vivo veritasQ29547620
ATP mediates rapid microglial response to local brain injury in vivoQ29547872
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertionQ29618089
Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cordQ29619388
Microglial physiology: unique stimuli, specialized responsesQ29620417
Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactionsQ30484049
An electron-microscopic analysis of axonal alterations following blunt contusion of the spinal cord of the rhesus monkey (Macaca mulatta)Q31913872
Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury.Q33198766
Microglia processes block the spread of damage in the brain and require functional chloride channelsQ33433015
NO mediates microglial response to acute spinal cord injury under ATP control in vivoQ33578042
SOCS1 and SOCS3 in the control of CNS immunityQ33717795
Molecular insights on the cerebral innate immune systemQ35077014
Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophagesQ35115047
Microglia: scapegoat, saboteur, or something else?Q35606301
The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degenerationQ35836498
Intratumoural injection of the toll-like receptor-2/6 agonist 'macrophage-activating lipopeptide-2' in patients with pancreatic carcinoma: a phase I/II trialQ36611097
Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodentsQ37128209
Repertoire of microglial and macrophage responses after spinal cord injuryQ37889633
TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptorsQ38132733
Electron Microscopic Observations of the Mechanisms of Terminal Club Formation in Transected Spinal Cord AxonsQ39418340
Lipoteichoic acid induces unique inflammatory responses when compared to other toll-like receptor 2 ligandsQ39851893
Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cellsQ41728928
Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in miceQ42110554
Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injuryQ42606175
Optic nerve and vitreal inflammation are both RGC neuroprotective but only the latter is RGC axogenicQ43245498
Stimulation of axon regeneration in the mature optic nerve by intravitreal application of the toll-like receptor 2 agonist Pam3Cys.Q43297236
Nile red as a polarity-sensitive fluorescent probe of hydrophobic protein surfacesQ43574073
Pathological changes from acute to chronic in experimental spinal cord traumaQ44132444
Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transportQ45216891
Myelin-induced microglial neurotoxicity can be controlled by microglial metabotropic glutamate receptors.Q45394547
Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitorsQ46614579
Intracutaneous injection of the macrophage-activating lipopeptide-2 (MALP-2) which accelerates wound healing in mice--a phase I trial in 12 patientsQ46711706
Effects of silica on the outcome from experimental spinal cord injury: implication of macrophages in secondary tissue damageQ46779870
Selective chemokine mRNA accumulation in the rat spinal cord after contusion injuryQ47711401
Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cordQ48129257
Long-term effects of methylprednisolone following transection of adult rat spinal cordQ48177004
Characterization of the early neuroinflammation after spinal cord injury in miceQ48244337
Kinetics of proinflammatory monocytes in a model of multiple sclerosis and its perturbation by laquinimodQ48454882
The neuropathological and behavioral consequences of intraspinal microglial/macrophage activationQ48543327
Nitric oxide via macrophage iNOS induces apoptosis following traumatic spinal cord injuryQ49105945
Disorganized microtubules underlie the formation of retraction bulbs and the failure of axonal regeneration.Q50668696
Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved.Q50707768
System xc- and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes.Q52578854
IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury.Q54509473
Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats.Q55067631
P433issuePt 3
P407language of work or nameEnglishQ1860
P921main subjectmicrogliaQ1622829
toll-like receptorQ408004
P304page(s)707-723
P577publication date2013-12-24
P1433published inBrainQ897386
P1476titleToll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury
P478volume137