scholarly article | Q13442814 |
P2093 | author name string | M J Solomon | |
J L Burton | |||
P2860 | cites work | Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis | Q24545581 |
Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1 | Q24600785 | ||
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation | Q24601346 | ||
The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1 | Q24608202 | ||
Regulation of APC activity by phosphorylation and regulatory factors | Q24683455 | ||
Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast. | Q27930025 | ||
APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5. | Q27930193 | ||
Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14. | Q27930227 | ||
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. | Q27930914 | ||
Ubiquitin-dependent protein degradation | Q27931143 | ||
Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex | Q27933305 | ||
Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae | Q27933953 | ||
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex | Q27934075 | ||
Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast. | Q27935011 | ||
The morphogenesis checkpoint in Saccharomyces cerevisiae: cell cycle control of Swe1p degradation by Hsl1p and Hsl7p | Q27937115 | ||
An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast | Q27938525 | ||
Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis | Q27938760 | ||
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p | Q27939049 | ||
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. | Q27940059 | ||
Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure | Q28131658 | ||
Cyclin is degraded by the ubiquitin pathway | Q28131704 | ||
Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis | Q28140028 | ||
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1 | Q28282074 | ||
Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family | Q28288497 | ||
SCF and APC: the Yin and Yang of cell cycle regulated proteolysis | Q28294742 | ||
How proteolysis drives the cell cycle | Q28297983 | ||
Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast | Q28300714 | ||
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p | Q29615276 | ||
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase | Q29618007 | ||
Whose end is destruction: cell division and the anaphase-promoting complex | Q29618257 | ||
Yeast Hct1 is a regulator of Clb2 cyclin proteolysis | Q29618399 | ||
Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast | Q29618547 | ||
The ubiquitin-proteasome proteolytic pathway | Q29618638 | ||
The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae | Q29620201 | ||
Hsl1p, a Swe1p inhibitor, is degraded via the anaphase-promoting complex | Q30453575 | ||
Subunits and substrates of the anaphase-promoting complex | Q33604656 | ||
Human p55(CDC)/Cdc20 associates with cyclin A and is phosphorylated by the cyclin A-Cdk2 complex | Q33890505 | ||
A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression | Q33968253 | ||
Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle. | Q34329439 | ||
Cut2 proteolysis required for sister-chromatid seperation in fission yeast | Q34733084 | ||
Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex | Q35081283 | ||
A cell cycle checkpoint monitors cell morphogenesis in budding yeast | Q36235503 | ||
Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae | Q36236630 | ||
Sequence analysis of temperature-sensitive mutations in the Saccharomyces cerevisiae gene CDC28. | Q36900442 | ||
A late mitotic regulatory network controlling cyclin destruction in Saccharomyces cerevisiae. | Q36913285 | ||
A complex degradation signal in Cyclin A required for G1 arrest, and a C-terminal region for mitosis | Q39645216 | ||
APC(ste9/srw1) promotes degradation of mitotic cyclins in G(1) and is inhibited by cdc2 phosphorylation. | Q40392447 | ||
Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway. | Q40805517 | ||
Proteolysis and the G1-S transition: the SCF connection | Q41732732 | ||
Cdk1 is essential for mammalian cyclosome/APC regulation | Q42805059 | ||
Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase | Q46760600 | ||
The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosis | Q47889973 | ||
Separation of sister chromatids in mitosis requires the Drosophila pimples product, a protein degraded after the metaphase/anaphase transition | Q48066968 | ||
P433 | issue | 18 | |
P304 | page(s) | 2381-2395 | |
P577 | publication date | 2001-09-01 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p | |
P478 | volume | 15 |
Q28073361 | A decade of the anaphase-promoting complex in the nervous system |
Q27931891 | A novel destruction sequence targets the meiotic regulator Spo13 for anaphase-promoting complex-dependent degradation in anaphase I. |
Q42271247 | A novel motif governs APC-dependent degradation of Drosophila ORC1 in vivo. |
Q24300108 | APC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathway |
Q64987048 | APC/C: current understanding and future perspectives. |
Q24291991 | APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex |
Q41766430 | Acm1 contributes to nuclear positioning by inhibiting Cdh1-substrate interactions |
Q27933747 | Acm1 is a negative regulator of the CDH1-dependent anaphase-promoting complex/cyclosome in budding yeast. |
Q27937054 | Ama1p-activated anaphase-promoting complex regulates the destruction of Cdc20p during meiosis II. |
Q35840276 | An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination |
Q24539034 | An architectural map of the anaphase-promoting complex |
Q27934623 | Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism. |
Q35083422 | Anaphase promoting complex-dependent degradation of transcriptional repressors Nrm1 and Yhp1 in Saccharomyces cerevisiae |
Q83099487 | Anaphase-promoting complex/cyclosome controls HEC1 stability |
Q36111232 | Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain |
Q38975034 | Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex. |
Q47756628 | CDKB1;1 forms a functional complex with CYCA2;3 to suppress endocycle onset |
Q34985452 | CPAP is a cell-cycle regulated protein that controls centriole length |
Q79108315 | Can Fizzy fly solo? |
Q27932430 | Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1) |
Q44734167 | Cell cycle-regulated recognition of the destruction box of cyclin B by the APC/C in Xenopus egg extracts |
Q34099210 | Cell cycle: Waiters serving the Destruction machinery |
Q34645278 | Changes in the localization of the Saccharomyces cerevisiae anaphase-promoting complex upon microtubule depolymerization and spindle checkpoint activation |
Q42944697 | Co-activator independent differences in how the metaphase and anaphase APC/C recognise the same substrate. |
Q42149849 | Coactivator functions in a stoichiometric complex with anaphase-promoting complex/cyclosome to mediate substrate recognition |
Q37095265 | Coordinate action of distinct sequence elements localizes checkpoint kinase Hsl1 to the septin collar at the bud neck in Saccharomyces cerevisiae |
Q92913542 | Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C |
Q35013072 | Cyclin destruction in mitosis: a crucial task of Cdc20. |
Q74144066 | Degradation of human Aurora-A protein kinase is mediated by hCdh1 |
Q75292418 | Destruction with a box: substrate recognition by the anaphase-promoting complex |
Q27932624 | Detection of protein-protein interactions at the septin collar in Saccharomyces cerevisiae using a tripartite split-GFP system |
Q24530195 | Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1 |
Q27929907 | Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition. |
Q47071909 | Drosophilasecurin destruction involves a D-box and a KEN-box and promotes anaphase in parallel with Cyclin A degradation |
Q24322917 | Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C |
Q27678304 | Electron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdown |
Q28343954 | Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins |
Q40353560 | Enzymology of the anaphase-promoting complex. |
Q50664506 | Fission yeast Mes1p ensures the onset of meiosis II by blocking degradation of cyclin Cdc13p. |
Q40707197 | Fizzy-related RNA expression patterns in mammalian development and cell lines |
Q38103251 | Flipping the switch from g1 to s phase with e3 ubiquitin ligases |
Q24683190 | Functional importance of the anaphase-promoting complex-Cdh1-mediated degradation of TMAP/CKAP2 in regulation of spindle function and cytokinesis |
Q21262000 | Genomic evolution and complexity of the Anaphase-promoting Complex (APC) in land plants |
Q41899907 | Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae |
Q40724282 | Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1. |
Q35787361 | Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit |
Q24328862 | Identification of a physiological E2 module for the human anaphase-promoting complex |
Q34438551 | Identification of anaphase promoting complex substrates in S. cerevisiae |
Q36489137 | Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1 |
Q36173872 | Identification of yeast IQGAP (Iqg1p) as an anaphase-promoting-complex substrate and its role in actomyosin-ring-independent cytokinesis. |
Q34576409 | In vivo characterization of the nonessential budding yeast anaphase-promoting complex/cyclosome components Swm1p, Mnd2p and Apc9p |
Q27937017 | Inhibition of APCCdh1 activity by Cdh1/Acm1/Bmh1 ternary complex formation |
Q36321649 | Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase |
Q30621924 | Insights into the cellular mechanism of the yeast ubiquitin ligase APC/C-Cdh1 from the analysis of in vivo degrons |
Q35677350 | Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint |
Q24610309 | Mammalian Cdh1/Fzr mediates its own degradation |
Q27936984 | Mechanisms of pseudosubstrate inhibition of the anaphase promoting complex by Acm1. |
Q37623965 | Mechanisms of ubiquitin transfer by the anaphase-promoting complex. |
Q27937430 | Meiosis-specific destruction of the Ume6p repressor by the Cdc20-directed APC/C |
Q30653286 | Molecular architecture and mechanism of the anaphase-promoting complex |
Q37071780 | Mutually dependent degradation of Ama1p and Cdc20p terminates APC/C ubiquitin ligase activity at the completion of meiotic development in yeast |
Q28206426 | Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation |
Q99638526 | Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit |
Q36990776 | Phosphorylation-triggered CUEDC2 degradation promotes UV-induced G1 arrest through APC/C(Cdh1) regulation. |
Q37863285 | Processive ubiquitin chain formation by the anaphase-promoting complex. |
Q27934263 | Pseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation |
Q56886511 | Purification and Assay of the Budding Yeast Anaphase‐Promoting Complex |
Q35567086 | RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex |
Q35048759 | Radmis, a novel mitotic spindle protein that functions in cell division of neural progenitors |
Q34277719 | Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover |
Q39256977 | Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C). |
Q42186985 | Regulated degradation of the APC coactivator Cdc20 |
Q39152605 | Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. |
Q92106577 | Regulation of Cell Cycle Entry and Exit: A Single Cell Perspective |
Q28754915 | Regulation of glia number in Drosophila by Rap/Fzr, an activator of the anaphase-promoting complex, and Loco, an RGS protein |
Q42604573 | Regulation of nuclear envelope dynamics via APC/C is necessary for the progression of semi-open mitosis in Schizosaccharomyces japonicus. |
Q34479142 | Roles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding |
Q35939885 | Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint. |
Q46657284 | S-phase checkpoint controls mitosis via an APC-independent Cdc20p function |
Q34278659 | Securin and B-cyclin/CDK are the only essential targets of the APC. |
Q27304773 | Sensing a bud in the yeast morphogenesis checkpoint: a role for Elm1. |
Q27342181 | Sgo1 recruits PP2A to chromosomes to ensure sister chromatid bi-orientation during mitosis. |
Q36867692 | State of the APC/C: organization, function, and structure |
Q37956288 | Structural insights into anaphase-promoting complex function and mechanism |
Q36378304 | Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1. |
Q41100050 | Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome |
Q37811107 | Structure, function and mechanism of the anaphase promoting complex (APC/C) |
Q41617016 | Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor |
Q41792135 | Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1. |
Q35081283 | Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex |
Q52118880 | The APC regulator CDH1 is essential for the progression of embryonic cell cycles in Xenopus. |
Q28749570 | The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit |
Q42679300 | The Arabidopsis anaphase-promoting complex/cyclosome subunit 1 is critical for both female gametogenesis and embryogenesis(F). |
Q27935255 | The Doc1 subunit is a processivity factor for the anaphase-promoting complex. |
Q36029051 | The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis |
Q27677351 | The Four Canonical TPR Subunits of Human APC/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a TPR Suprahelix |
Q24515254 | The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis |
Q29618398 | The anaphase promoting complex/cyclosome: a machine designed to destroy |
Q30485996 | The anaphase-promoting complex promotes actomyosin-ring disassembly during cytokinesis in yeast. |
Q35636466 | The anaphase-promoting complex/cyclosome is required for anaphase progression in multinucleated Ashbya gossypii cells |
Q36022931 | The anaphase-promoting complex: a key factor in the regulation of cell cycle |
Q28610045 | The anaphase-promoting complex: proteolysis in mitosis and beyond |
Q33552315 | The onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate c-myc target genes in mammalian tumor cells |
Q41815602 | The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C). |
Q24534348 | Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes |
Q29617992 | Ubiquitin ligases: cell-cycle control and cancer |
Q24304257 | Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1 |
Q27938098 | Unique D box and KEN box sequences limit ubiquitination of Acm1 and promote pseudosubstrate inhibition of the anaphase-promoting complex |
Q38487804 | Using Drosophila eye as a model system to characterize the function of mars gene in cell-cycle regulation |
Q47105112 | Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C). |
Q39756669 | Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway |