| P50 | author | Claude F Burgoyne | Q63153020 |
| | Claude Burgoyne | Q67940450 |
| P2860 | cites work | Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human optic nerve head astrocytes | Q28204043 |
| | The way things move: looking under the hood of molecular motor proteins | Q29617532 |
| | Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides | Q30480995 |
| | Ganglion cell losses underlying visual field defects from experimental glaucoma. | Q30767440 |
| | Experimental optic cup enlargement caused by endothelin-1-induced chronic optic nerve head ischemia | Q30806728 |
| | Swelling and loss of photoreceptors in chronic human and experimental glaucomas | Q30839393 |
| | Cerebrospinal fluid pressure in glaucoma: a prospective study | Q84998936 |
| | Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey | Q39432089 |
| | Clinical quality assessment using computer monitor photoimages of optic nerve head cupping | Q39545684 |
| | Three-dimensional reconstruction of normal and early glaucoma monkey optic nerve head connective tissues. | Q39700990 |
| | 3-D histomorphometry of the normal and early glaucomatous monkey optic nerve head: prelaminar neural tissues and cupping | Q39818990 |
| | Optic nerve dynein motor protein distribution changes with intraocular pressure elevation in a rat model of glaucoma | Q40341960 |
| | Ganglion cell death in glaucoma: pathology recapitulates ontogeny | Q40405291 |
| | Mechanisms of optic nerve damage in primary open angle glaucoma | Q40640046 |
| | Age changes of the human optic nerve head. A neurohistologic study | Q40650886 |
| | Neuronal death in glaucoma | Q40827206 |
| | Glaucomatous optic nerve cupping as an optic neuropathy | Q40911542 |
| | Glaucomatous cupping of the human optic disk: a neuro-histologic study | Q41066195 |
| | Ultrastructural location of extracellular matrix components in the optic nerve head | Q41248118 |
| | The effect of panretinal photocoagulation on optic nerve cupping | Q41304376 |
| | The optic nerve head in glaucomatous optic neuropathy | Q41390007 |
| | Leber hereditary optic neuropathy: how do mitochondrial DNA mutations cause degeneration of the optic nerve? | Q41547379 |
| | Nonglaucomatous excavation of the optic disc | Q41644362 |
| | Cupping of the optic disc in ischemic optic neuropathy | Q41788324 |
| | Vasogenic origin of visual field defects and optic nerve changes in glaucoma | Q42156313 |
| | Astrocytes in glaucomatous optic neuropathy | Q42600591 |
| | Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice | Q42914157 |
| | In vitro evaluation of reactive astrocyte migration, a component of tissue remodeling in glaucomatous optic nerve head | Q43592546 |
| | Immunohistologic evidence for retinal glial cell changes in human glaucoma | Q43940019 |
| | Human optic nerve head astrocytes as a target for endothelin-1. | Q44082587 |
| | Effects of endothelin-1 on components of anterograde axonal transport in optic nerve. | Q44161057 |
| | Various glaucomatous optic nerve appearances: clinical correlations | Q44607031 |
| | High-pass resolution perimetry and age-related loss of visual pathway neurons | Q44634321 |
| | Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA/2NNia glaucomatous mice: comparison with RGC loss in aging C57/BL6 mice | Q44669093 |
| | Macular degeneration and glaucoma-like optic nerve head cupping | Q44963908 |
| | Calcium transients in astrocyte endfeet cause cerebrovascular constrictions | Q45051047 |
| | Regional optic nerve damage in experimental mouse glaucoma | Q45158779 |
| | Retinal ganglion cell damage in human glaucoma. 2. Studies on damage pattern | Q45248966 |
| | Mechanisms of maturation and ageing of collagen | Q45345441 |
| | The structural relationship between the microvasculature, neurons, and glia in the human retina. | Q45915584 |
| | Intracellular flow in optic nerve axons: a mechanism for cell death in glaucoma. | Q46029796 |
| | Upregulation of EphB2 and ephrin-B2 at the optic nerve head of DBA/2J glaucomatous mice coincides with axon loss | Q46174787 |
| | Peripapillary retinal nerve fibre layer thickness in highly myopic Caucasians as measured by Stratus optical coherence tomography | Q46513052 |
| | Time-dependent effects of elevated intraocular pressure on optic nerve head axonal transport and cytoskeleton proteins | Q46713852 |
| | Acute endothelin-1 application induces reversible fast axonal transport blockade in adult rat optic nerve | Q46713858 |
| | Modeling individual-specific human optic nerve head biomechanics. Part I: IOP-induced deformations and influence of geometry | Q46726427 |
| | Factors influencing optic nerve head biomechanics | Q46774812 |
| | Microtubules contribute to the birefringence of the retinal nerve fiber layer | Q46816883 |
| | Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head | Q47263642 |
| | Ultrastructure of Human and Monkey Lamina Cribrosa and Optic Nerve Head | Q47677685 |
| | Modeling individual-specific human optic nerve head biomechanics. Part II: influence of material properties | Q47887071 |
| | The cupped disc. Who needs neuroimaging? | Q48366783 |
| | Trans-lamina cribrosa pressure difference | Q48474876 |
| | The distribution of mitochondrial activity in relation to optic nerve structure | Q48587524 |
| | Atrophy of relay neurons in magno- and parvocellular layers in the lateral geniculate nucleus in experimental glaucoma | Q48701835 |
| | Age-related changes of scleral hydration and sulfated glycosaminoglycans. | Q50766795 |
| | Effect of aging on retinal macular microcirculation: a blue field simulation study. | Q50777799 |
| | An in vivo model of chronic optic nerve ischemia: the dose-dependent effects of endothelin-1 on the optic nerve microvasculature. | Q50983673 |
| | Connective tissue structure of the tree shrew optic nerve and associated ageing changes. | Q51017820 |
| | Childhood glaucoma: results with trabeculotomy and study of reversible cupping. | Q51862341 |
| | Heterogeneity of astrocytes in human optic nerve head. | Q52204693 |
| | Frequency of sustained glaucomatous-type visual field loss and associated optic nerve cupping in Beaver Dam, Wisconsin. | Q53880570 |
| | Astrocyte responses in human optic nerve head with primary open-angle glaucoma. | Q53963585 |
| | Tropoelastin gene expression in optic nerve heads of normal and glaucomatous subjects. | Q53979885 |
| | Aging affects the retrobulbar circulation differently in women and men. | Q54042602 |
| | The histology of human glaucoma cupping and optic nerve damage: clinicopathologic correlation in 21 eyes | Q67007931 |
| | Distribution of axonal and glial elements in the rhesus optic nerve head studied by electron microscopy | Q67524818 |
| | Cell culture of the human lamina cribrosa | Q68123354 |
| | The size and shape of the optic disc in normal human eyes | Q68697074 |
| | Aging changes of the rhesus monkey optic nerve | Q68890120 |
| | Age-related changes in the extracellular matrix of the human optic nerve head | Q69498792 |
| | Structural proteins of the neonatal and adult lamina cribrosa | Q69674162 |
| | The effect of age on normal human optic nerve fiber number and diameter | Q69950027 |
| | Experimental glaucoma in monkeys. I. Relationship between intraocular pressure and cupping of the optic disc and cavernous atrophy of the optic nerve | Q69987595 |
| | Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve | Q70023645 |
| | Localization of collagen types I and IV mRNAs in human optic nerve head by in situ hybridization | Q70231128 |
| | Age related compliance of the lamina cribrosa in human eyes | Q30840922 |
| | Deformation of the lamina cribrosa and anterior scleral canal wall in early experimental glaucoma. | Q30884323 |
| | Visual field and optic disc progression in patients with different types of optic disc damage: a longitudinal prospective study | Q31022707 |
| | Model of endothelin-1-induced chronic optic neuropathy in rat. | Q31033953 |
| | Effect of intraocular pressure on optic disc topography, electroretinography, and axonal loss in a chronic pressure-induced rat model of optic nerve damage. | Q31106016 |
| | Tri-dimensional morphometric analysis of astrocytic processes with high voltage electron microscopy of thick Golgi preparations | Q31120011 |
| | Differential expression of matrix metalloproteinases in monkey eyes with experimental glaucoma or optic nerve transection | Q31135940 |
| | Morphology of single ganglion cells in the glaucomatous primate retina | Q31980685 |
| | Optic disc movement with variations in intraocular and cerebrospinal fluid pressure. | Q33184743 |
| | Viscoelastic material properties of the peripapillary sclera in normal and early-glaucoma monkey eyes. | Q33211207 |
| | Decreased photoreceptor count in human eyes with secondary angle-closure glaucoma | Q33229177 |
| | Topographic and morphologic analyses of retinal ganglion cell loss in old DBA/2NNia mice | Q33241126 |
| | The genetics of axonal transport and axonal transport disorders | Q33258819 |
| | Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric | Q33259237 |
| | Three-dimensional histomorphometry of the normal and early glaucomatous monkey optic nerve head: neural canal and subarachnoid space architecture | Q33288804 |
| | 3-D histomorphometry of the normal and early glaucomatous monkey optic nerve head: lamina cribrosa and peripapillary scleral position and thickness. | Q33300537 |
| | Intravitreal colchicine causes decreased RNFL birefringence without altering RNFL thickness. | Q33313064 |
| | Relative course of retinal nerve fiber layer birefringence and thickness and retinal function changes after optic nerve transection | Q33345174 |
| | Remodeling of the connective tissue microarchitecture of the lamina cribrosa in early experimental glaucoma | Q33370876 |
| | Rates of neuroretinal rim and peripapillary atrophy area change: a comparative study of glaucoma patients and normal controls | Q33438142 |
| | The role of cerebrospinal fluid pressure in glaucoma pathophysiology: the dark side of the optic disc | Q33440519 |
| | In vivo imaging of retinal ganglion cell axons within the nerve fiber layer | Q33508056 |
| | Axonal/glial upregulation of EphB/ephrin-B signaling in mouse experimental ocular hypertension | Q33509467 |
| | Laser-induced ocular hypertension in albino CD-1 mice | Q33509472 |
| | Quantification of dynamic blood flow autoregulation in optic nerve head of rhesus monkeys | Q33512188 |
| | Acquired cupping of the optic nerve head in normotensive eyes | Q33649383 |
| | Deformation of the normal monkey optic nerve head connective tissue after acute IOP elevation within 3-D histomorphometric reconstructions | Q33835700 |
| | The optic nerve head in glaucoma: role of astrocytes in tissue remodeling | Q33882462 |
| | Glaucomatous versus nonglaucomatous optic disc cupping: clinical differentiation | Q33887315 |
| | Optic nerve head structure in glaucoma: astrocytes as mediators of axonal damage | Q34057614 |
| | Nonglaucomatous cupping of the optic disc | Q34151382 |
| | The prevalence of cupping in end-stage arteritic and nonarteritic anterior ischemic optic neuropathy | Q34174469 |
| | Nocturnal arterial hypotension and its role in optic nerve head and ocular ischemic disorders | Q34340412 |
| | The anatomy and pathophysiology of the optic nerve head in glaucoma | Q34559887 |
| | Cargo transport: two motors are sometimes better than one. | Q34639565 |
| | Deformation of the early glaucomatous monkey optic nerve head connective tissue after acute IOP elevation in 3-D histomorphometric reconstructions | Q34646694 |
| | Astrocyte control of the cerebrovasculature. | Q34656875 |
| | Endothelin: is it a contributor to glaucoma pathophysiology? | Q34760872 |
| | Axonal transport of membranous and nonmembranous cargoes: a unified perspective | Q35087179 |
| | Effects of retinal ganglion cell loss on magno-, parvo-, koniocellular pathways in the lateral geniculate nucleus and visual cortex in glaucoma | Q35125723 |
| | Histochemical localisation of mitochondrial enzyme activity in human optic nerve and retina | Q35308734 |
| | Age related changes in the non-collagenous components of the extracellular matrix of the human lamina cribrosa | Q35313742 |
| | Optic disc morphology of patients with OPA1 autosomal dominant optic atrophy | Q35590374 |
| | The distributions of mitochondria and sodium channels reflect the specific energy requirements and conduction properties of the human optic nerve head | Q35591713 |
| | Does the intraocular pressure effect on optic disc cupping differ by age? | Q35662695 |
| | Age-related changes in the thickness of the human lamina cribrosa | Q35762804 |
| | Redefining the concept of reactive astrocytes as cells that remain within their unique domains upon reaction to injury | Q35768729 |
| | Anterior scleral canal geometry in pressurised (IOP 10) and non-pressurised (IOP 0) normal monkey eyes. | Q35895203 |
| | Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model | Q35945481 |
| | The optic nerve head as a biomechanical structure: a new paradigm for understanding the role of IOP-related stress and strain in the pathophysiology of glaucomatous optic nerve head damage | Q35957595 |
| | The axonal transport of mitochondria. | Q36321480 |
| | Pathological optic-disc cupping | Q36377536 |
| | Laser-induced primate glaucoma. I. Progression of cupping | Q36612626 |
| | Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma | Q36639100 |
| | Comparison of Ganglion Cell Loss and Cone Loss in Experimental Glaucoma | Q36690076 |
| | Axoplasmic flow during chronic experimental glaucoma. 1. Light and electron microscopic studies of the monkey optic nervehead during development of glaucomatous cupping | Q36743437 |
| | Endothelin-1 mediated regulation of extracellular matrix collagens in cells of human lamina cribrosa | Q36772324 |
| | An endothelin-1 induced model of optic nerve ischemia in the rabbit | Q36813939 |
| | Cerebrospinal fluid pressure is decreased in primary open-angle glaucoma | Q37152987 |
| | Premise and prediction-how optic nerve head biomechanics underlies the susceptibility and clinical behavior of the aged optic nerve head | Q37190892 |
| | Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand | Q37195253 |
| | Friend or foe? Resolving the impact of glial responses in glaucoma | Q37230041 |
| | Intracranial pressure in primary open angle glaucoma, normal tension glaucoma, and ocular hypertension: a case-control study | Q37249233 |
| | Changes in the collagenous matrix of the aging human lamina cribrosa | Q37311482 |
| | Physiologic intereye differences in monkey optic nerve head architecture and their relation to changes in early experimental glaucoma | Q37366021 |
| | Biomechanics of the optic nerve head | Q37393415 |
| | The dynamics and location of axonal transport blockade by acute intraocular pressure elevation in primate optic nerve | Q39395169 |
| | Evidence of constriction of optic nerve axons at the lamina cribrosa in the normotensive eye in humans and other mammals | Q70875941 |
| | The mode of progressive disc cupping in ocular hypertension and glaucoma | Q71153898 |
| | The effect of age on the nerve fiber population of the human optic nerve | Q71380247 |
| | Aging of the optic nerve | Q71390479 |
| | An endothelin-1-induced model of chronic optic nerve ischemia in rhesus monkeys | Q71508796 |
| | Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma | Q71722798 |
| | Programmed cell death of retinal ganglion cells during experimental glaucoma | Q71735807 |
| | Development of cupping and pallor in posterior ischemic optic neuropathy | Q71827691 |
| | The effect of chronically elevated intraocular pressure on the rat optic nerve head extracellular matrix | Q71946144 |
| | Optic disc morphology in "age-related atrophic glaucoma" | Q71952323 |
| | The human optic nerve: fascicular organisation and connective tissue types along the extra-fascicular matrix | Q72065121 |
| | Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis | Q72131673 |
| | The influence of cerebrospinal fluid pressure on the lamina cribrosa tissue pressure gradient | Q72190340 |
| | Miniature Passive Pressure Transensor for Implanting in the Eye | Q72366027 |
| | Primary open-angle glaucoma is not associated with photoreceptor loss | Q72410719 |
| | Optic disc cupping in arteritic anterior ischemic optic neuropathy | Q72520428 |
| | Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage | Q72633267 |
| | Quantitative analysis of optic disc cupping in compressive optic neuropathy | Q72634541 |
| | Inhibition of retrograde axoplasmic transport in rat optic nerve by increased IOP in vitro | Q72720464 |
| | Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats | Q73006494 |
| | Documented optic disc cupping in compressive optic neuropathy | Q73212484 |
| | Effects of age on nerve fibers in the rhesus monkey optic nerve | Q73338960 |
| | Chronology of optic nerve head and retinal responses to elevated intraocular pressure | Q73437263 |
| | Loss of neurons in magnocellular and parvocellular layers of the lateral geniculate nucleus in glaucoma | Q73559509 |
| | Estimating normal optic nerve axon numbers in non-human primate eyes | Q73746835 |
| | Parapapillary chorioretinal atrophy in patients with ocular hypertension. II. An evaluation of progressive changes | Q73945193 |
| | Evidence for glaucoma-induced horizontal cell alterations in the human retina | Q74232870 |
| | Increased elastin expression in astrocytes of the lamina cribrosa in response to elevated intraocular pressure | Q74439946 |
| | Optic disc morphology after arteritic anterior ischemic optic neuropathy | Q74459202 |
| | Methanol-induced optic nerve cupping | Q74484991 |
| | The correlation between cerebrospinal fluid pressure and retrolaminar tissue pressure | Q74770880 |
| | Focal accumulation of intra-axonal mitochondria in demyelination of the cat optic nerve | Q77094754 |
| | Posterior scleral thickness in perfusion-fixed normal and early-glaucoma monkey eyes | Q77300534 |
| | Effects of age on the glial cells in the rhesus monkey optic nerve | Q77759250 |
| | Anatomic relationship between lamina cribrosa, intraocular space, and cerebrospinal fluid space | Q79323772 |
| | Microtubule contribution to the reflectance of the retinal nerve fiber layer | Q79377788 |
| | Contrast sensitivity changes due to glaucoma and normal aging: low-spatial-frequency losses in both magnocellular and parvocellular pathways | Q80219496 |
| | Lamina cribrosa thickness and spatial relationships between intraocular space and cerebrospinal fluid space in highly myopic eyes | Q80384804 |
| | Endothelin-1-mediated signaling in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in astrocytes | Q80673582 |
| | Circulation and axonal transport in the optic nerve | Q80981254 |
| | Age related optic nerve axonal loss in adult Brown Norway rats | Q81818750 |
| | Age-related macular degeneration and optic disk cupping: the Beaver Dam Eye Study | Q82613073 |
| | Interactions between geometry and mechanical properties on the optic nerve head | Q83237037 |
| | Lamina cribrosa and peripapillary sclera histomorphometry in normal and advanced glaucomatous Chinese eyes with various axial length | Q83705784 |
| | The role of endothelin-1 and its receptors in optic nerve head astrocyte proliferation | Q84284271 |
| | 3D morphometry of the human optic nerve head | Q84579469 |
| | Laminar and prelaminar tissue displacement during intraocular pressure elevation in glaucoma patients and healthy controls | Q84591558 |
| | Hypothesis concerning the pathophysiology of optic nerve damage in open angle glaucoma | Q84917812 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | biomechanics | Q193378 |
| P304 | page(s) | 120-132 | |
| P577 | publication date | 2010-09-16 | |
| P1433 | published in | Experimental Eye Research | Q15754753 |
| P1476 | title | A biomechanical paradigm for axonal insult within the optic nerve head in aging and glaucoma | |
| P478 | volume | 93 | |