Effects of angiotensin II type 2 receptor overexpression on the growth of hepatocellular carcinoma cells in vitro and in vivo

scientific article

Effects of angiotensin II type 2 receptor overexpression on the growth of hepatocellular carcinoma cells in vitro and in vivo is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2013PLoSO...883754D
P356DOI10.1371/JOURNAL.PONE.0083754
P932PMC publication ID3877089
P698PubMed publication ID24391821
P5875ResearchGate publication ID259589356

P50authorColin SumnersQ64025382
P2093author name stringMing Li
Yanling Zhang
Yi Zhang
Zhi Huang
Hongyan Du
Hongwei Li
Baihong Chen
Yang Fei
Andrew Li
Jinlong Li
Suihai Wang
Feilong Jie
Nana Pei
Zhibing Liang
P2860cites workGlobal cancer statisticsQ22241238
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer modelQ24655262
Blockage of angiotensin II type I receptor decreases the synthesis of growth factors and induces apoptosis in C6 cultured cells and C6 rat gliomaQ28211260
The angiotensin II type 2 receptor causes constitutive growth of cardiomyocytes and does not antagonize angiotensin II type 1 receptor-mediated hypertrophyQ28281648
Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and FasL-Fas engagementQ28568716
Highly specific expression of luciferase gene in lungs of naïve nude mice directed by prostate-specific antigen promoterQ30437533
Antiangiogenic effect of angiotensin II type 2 receptor in ischemia-induced angiogenesis in mice hindlimb.Q31065290
Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivationQ31805054
Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic miceQ33534042
AAV's anatomy: roadmap for optimizing vectors for translational successQ33659389
Hemizygous mice for the angiotensin II type 2 receptor gene have attenuated susceptibility to azoxymethane-induced colon tumorigenesis.Q52546658
Role of angiotensin II-regulated apoptosis through distinct AT1 and AT2 receptors in neointimal formationQ74605937
Angiotensin II induces apoptosis in intestinal epithelial cells through the AT2 receptor, GATA-6 and the Bax pathwayQ84549479
Expression of bone morphogenetic protein-2 and its receptors in epithelial ovarian cancer and their influence on the prognosis of ovarian cancer patientsQ34008631
Adeno-associated virus vectorology, manufacturing, and clinical applicationsQ34172314
Over-expression of angiotensin II type 2 receptor gene induces cell death in lung adenocarcinoma cellsQ34280097
Ligand-independent signals from angiotensin II type 2 receptor induce apoptosisQ34731369
Persistent proteinuria up-regulates angiotensin II type 2 receptor and induces apoptosis in proximal tubular cellsQ35097995
Adenovirus-associated virus vector-mediated gene transfer in hemophilia BQ35691659
Intratracheal administration of a nanoparticle-based therapy with the angiotensin II type 2 receptor gene attenuates lung cancer growthQ36594271
Angiotensin II type 1 receptor expression in ovarian cancer and its correlation with tumour angiogenesis and patient survivalQ36613817
Moderate cardiac-selective overexpression of angiotensin II type 2 receptor protects cardiac functions from ischaemic injuryQ36748599
Clinical gene therapy using recombinant adeno-associated virus vectorsQ37140649
Gene therapy clinical trials worldwide to 2012 - an update.Q38077166
The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cellsQ38299038
Delineation of the effects of angiotensin type 1 and 2 receptors on HL-1 cardiomyocyte apoptosisQ39360166
RN181 suppresses hepatocellular carcinoma growth by inhibition of the ERK/MAPK pathwayQ39578288
Angiotensin type 2 receptor-mediated apoptosis of human prostate cancer cellsQ39765517
Antiproliferative activity of angiotensin II receptor blocker through cross-talk between stromal and epithelial prostate cancer cellsQ40353409
Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K2 and angiotensin-converting enzyme inhibitor via anti-angiogenic activities.Q40367712
Intronic enhancement of angiotensin II type 2 receptor transgene expression in vitro and in vivoQ40381528
Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal disseminationQ40438044
Combination of interferon-beta and the angiotensin-converting enzyme inhibitor, perindopril, attenuates murine hepatocellular carcinoma development and angiogenesis.Q40542869
Differential regulation of in vivo angiogenesis by angiotensin II receptorsQ40620209
Angiotensin II receptors and angiotensin II receptor antagonists.Q40846126
Molecular and cellular mechanism of angiotensin II-mediated apoptosisQ40980902
Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.Q42503774
Endgame: glybera finally recommended for approval as the first gene therapy drug in the European unionQ42516930
Dysregulation of apoptosis in hepatocellular carcinoma cellsQ43166036
Deficiency or blockade of angiotensin II type 2 receptor delays tumorigenesis by inhibiting malignant cell proliferation and angiogenesisQ43167619
Blockade of angiotensin AT1a receptor signaling reduces tumor growth, angiogenesis, and metastasisQ44018962
Increased renal vascular endothelial growth factor and angiopoietins by angiotensin II infusion is mediated by both AT1 and AT2 receptorsQ44669197
Retinal expression of vascular endothelial growth factor is mediated by angiotensin type 1 and type 2 receptorsQ44725147
Arrestins block G protein-coupled receptor-mediated apoptosisQ44820320
Imaging transgene expression in live animalsQ45198958
Angiotensin type 1a receptor signaling-dependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor growthQ45214758
Combination of interferon and angiotensin-converting enzyme inhibitor, perindopril, suppresses liver carcinogenesis and angiogenesis in mice.Q45261608
Angiotensin II type 2 receptor gene deficiency attenuates susceptibility to tobacco-specific nitrosamine-induced lung tumorigenesis: involvement of transforming growth factor-beta-dependent cell growth attenuationQ46685681
Ventricular-specific expression of angiotensin II type 2 receptors causes dilated cardiomyopathy and heart failure in transgenic miceQ47752119
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
overexpressionQ61643320
P304page(s)e83754
P577publication date2013-12-31
P1433published inPLOS OneQ564954
P1476titleEffects of angiotensin II type 2 receptor overexpression on the growth of hepatocellular carcinoma cells in vitro and in vivo
P478volume8

Reverse relations

cites work (P2860)
Q38814333AT2R Gene Delivered by Condensed Polylysine Complexes Attenuates Lewis Lung Carcinoma after Intravenous Injection or Intratracheal Spray
Q36473924Adenovirus-Mediated Angiotensin II Type 2 Receptor Overexpression Inhibits Tumor Growth of Prostate Cancer In Vivo
Q33784943Angiotensin II type 2 receptor promotes apoptosis and inhibits angiogenesis in bladder cancer
Q40939536Angiotensin receptor blockers improve survival outcomes after radiofrequency ablation in hepatocarcinoma patients
Q36307866Angiotensin-(1-7) Suppresses Hepatocellular Carcinoma Growth and Angiogenesis via Complex Interactions of Angiotensin II Type 1 Receptor, Angiotensin II Type 2 Receptor and Mas Receptor
Q55127228Emerging Roles of G Protein-Coupled Receptors in Hepatocellular Carcinoma.
Q28078113Local ablative treatments for hepatocellular carcinoma: An updated review
Q38937272Overexpression of angiotensin II type 2 receptor promotes apoptosis and impairs insulin secretion in rat insulinoma cells
Q89640256Renin-angiotensin inhibitors were associated with improving outcomes of hepatocellular carcinoma with primary hypertension after hepatectomy
Q36400573Small-molecule AT2 receptor agonists
Q64098694Spontaneous Regression of Hepatocellular Carcinoma and Review of Reports in the Published English Literature
Q51326132Support for involvement of the renin-angiotensin system in dysplastic Barrett's esophagus.
Q92573164Systematic review: Renin-angiotensin system inhibitors in chemoprevention of hepatocellular carcinoma
Q46486488The ROS derived mitochondrial respirstion not from NADPH oxidase plays key role in Celastrol against angiotensin II-mediated HepG2 cell proliferation

Search more.