| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1517/14712598.3.2.227 |
| P8608 | Fatcat ID | release_yglab5vlwrbbvngpwefphiljbm |
| P698 | PubMed publication ID | 12662138 |
| P50 | author | Samia J. Khoury | Q37372486 |
| P2093 | author name string | Nader Najafian | |
| P2860 | cites work | ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28 | Q22001503 |
| Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS | Q28139731 | ||
| Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor | Q28144319 | ||
| CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis | Q37696199 | ||
| Fingerprints of anergic T cells | Q38300517 | ||
| The B7 and CD28 receptor families | Q40392461 | ||
| The role of CD40 in the regulation of humoral and cell-mediated immunity | Q40393797 | ||
| Potential roles of the B7 and CD28 receptor families in autoimmunity and immune evasion | Q40399427 | ||
| Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases | Q41151737 | ||
| Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells | Q41357447 | ||
| Homeostasis and self-tolerance in the immune system: turning lymphocytes off. | Q41735900 | ||
| Expression of the B7/BB1 Activation Antigen and its Ligand CD28 in T-Cell-Mediated Skin Diseases | Q42476510 | ||
| B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy | Q42675165 | ||
| Blockade of CD40-CD40 ligand pathway induces tolerance in murine contact hypersensitivity | Q45885519 | ||
| Elevated expression of CD80 (B7/BB1) and other accessory molecules on synovial fluid mononuclear cell subsets in rheumatoid arthritis | Q46515954 | ||
| Treatment of murine lupus with CTLA4Ig | Q46538983 | ||
| The role of T-cell costimulatory activation pathways in transplant rejection | Q47955940 | ||
| Functional responses and costimulator dependence of memory CD4+ T cells. | Q52030310 | ||
| Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. | Q54308518 | ||
| A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively | Q55888521 | ||
| Costimulatory blockade in patients with rheumatoid arthritis: a pilot, dose-finding, double-blind, placebo-controlled clinical trial evaluating CTLA-4Ig and LEA29Y eighty-five days after the first infusion | Q56904375 | ||
| ICOS co-stimulatory receptor is essential for T-cell activation and function | Q28187985 | ||
| PD-L2 is a second ligand for PD-1 and inhibits T cell activation | Q28202471 | ||
| CTLA-4 can function as a negative regulator of T cell activation | Q28235866 | ||
| The role of the CD28 receptor during T cell responses to antigen | Q28263234 | ||
| ICOS is critical for CD40-mediated antibody class switching | Q28589705 | ||
| ICOS is essential for effective T-helper-cell responses | Q28594859 | ||
| Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 | Q29619280 | ||
| Organ injury associated with extrathymic induction of immune tolerance in doubly transgenic mice | Q33610544 | ||
| Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis | Q33835268 | ||
| Finally, CTLA4Ig graduates to the clinic | Q33852345 | ||
| CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris | Q33855058 | ||
| CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis | Q33939286 | ||
| Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses | Q33971036 | ||
| CTLA4-Ig: a novel immunosuppressive agent | Q34075083 | ||
| Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation | Q34154374 | ||
| The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function | Q34165325 | ||
| Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness | Q35157542 | ||
| Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor alpha leads to autoimmunity in transgenic mice | Q35383976 | ||
| Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection | Q35939463 | ||
| Keratinocyte expression of B7-1 in transgenic mice amplifies the primary immune response to cutaneous antigens. | Q36003698 | ||
| CTLA-4 is a second receptor for the B cell activation antigen B7 | Q36230356 | ||
| Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells | Q36356623 | ||
| Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal | Q36361532 | ||
| Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse | Q36364541 | ||
| Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions | Q36365596 | ||
| CTLA-4: a negative regulator of autoimmune disease. | Q36367226 | ||
| Identification of a costimulatory molecule rapidly induced by CD40L as CD44H. | Q36367256 | ||
| Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis | Q36375265 | ||
| Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes | Q36400199 | ||
| Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation | Q36420205 | ||
| Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes | Q37358432 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 227-236 | |
| P577 | publication date | 2003-04-01 | |
| P1433 | published in | Expert Opinion on Biological Therapy | Q5421201 |
| P1476 | title | T cell costimulatory pathways: blockade for autoimmunity | |
| P478 | volume | 3 |
| Q23911107 | Association of Epstein-Barr virus with systemic lupus erythematosus - effect modification by race, age, and cytotoxic T lymphocyte-associate antigen 4 genotype |
| Q44822884 | B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis |
| Q33929056 | CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function |
| Q51035095 | Cross-regulation of CD86 by CD80 differentially regulates T helper responses from Mycobacterium tuberculosis secretory antigen-activated dendritic cell subsets. |
| Q39251222 | Dual Role of Fas/FasL-Mediated Signal in Peripheral Immune Tolerance. |
| Q36133140 | Immunotherapy for pancreatic cancer - science driving clinical progress |
| Q34540139 | Local administration of soluble CD40:Fc to the salivary glands of non-obese diabetic mice does not ameliorate autoimmune inflammation |
| Q41526144 | Overlooked Mechanisms in Type 1 Diabetes Etiology: How Unique Costimulatory Molecules Contribute to Diabetogenesis |
| Q36220691 | PD-1/PD-L1 blockade can enhance HIV-1 Gag-specific T cell immunity elicited by dendritic cell-directed lentiviral vaccines |
| Q51583682 | Regulation of Th1/Th2 balance through OX40/OX40L signalling by glycyrrhizic acid in a murine model of asthma. |
| Q55166882 | Roles of Host Immunity in Viral Myocarditis and Dilated Cardiomyopathy. |
| Q40325737 | Transfection of CD40 in a human oral squamous cell carcinoma keratinocyte line upregulates immune potency and costimulatory molecules |
| Q45069257 | Transplantation of islets transduced with CTLA4-Ig and TGFbeta using adenovirus and lentivirus vectors |
| Q35842612 | Using antibodies in tumour immunotherapy |
| Q80507353 | Xenogeneic cell transplant: fact or fancy? |
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