H5N1 influenza vaccine formulated with AS03 A induces strong cross-reactive and polyfunctional CD4 T-cell responses.

scientific article

H5N1 influenza vaccine formulated with AS03 A induces strong cross-reactive and polyfunctional CD4 T-cell responses. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10875-010-9490-6
P932PMC publication ID3132412
P698PubMed publication ID21174144
P5875ResearchGate publication ID49698518

P50authorMamadou DraméQ104748926
Frédéric ClementQ51751601
P2093author name stringPhilippe Moris
Emmanuel Hanon
Isabel Leroux-Roels
Marcelle Van Mechelen
Robbert van der Most
Geert G Leroux-Roels
P2860cites workFunctional and phenotypic characterization of tetanus toxoid-specific human CD4+ T cells following re-immunization.Q51976793
Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells.Q51985345
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Normal human CD4+ memory T cells display broad heterogeneity in their activation threshold for cytokine synthesisQ77573851
Broad Clade 2 cross-reactive immunity induced by an adjuvanted clade 1 rH5N1 pandemic influenza vaccineQ21144344
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineagesQ24642180
Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individualsQ24648051
Central memory and effector memory T cell subsets: function, generation, and maintenanceQ29615097
Cross-protection against lethal H5N1 challenge in ferrets with an adjuvanted pandemic influenza vaccineQ30229190
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Antigen sparing and cross-reactive immunity with an adjuvanted rH5N1 prototype pandemic influenza vaccine: a randomised controlled trial.Q30363500
Safety and reactogenicity profile of an adjuvanted H5N1 pandemic candidate vaccine in adults within a phase III safety trial.Q30368814
An adjuvanted, low-dose, pandemic influenza A (H5N1) vaccine candidate is safe, immunogenic, and induces cross-reactive immune responses in healthy adults.Q30370214
MF59-adjuvanted H5N1 vaccine induces immunologic memory and heterotypic antibody responses in non-elderly and elderly adultsQ30374764
Current status and progress of prepandemic and pandemic influenza vaccine development.Q30375975
Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine.Q30376757
Immunogenicity and tolerability of an AS03(A)-adjuvanted prepandemic influenza vaccine: a phase III study in a large population of Asian adults.Q30379899
Single dose vaccination with AS03-adjuvanted H5N1 vaccines in a randomized trial induces strong and broad immune responsiveness to booster vaccination in adults.Q30381923
The 2009 A (H1N1) influenza virus pandemic: A reviewQ30390380
Memory CD8 T-cell differentiation during viral infectionQ34152220
Understanding the generation and function of memory T cell subsetsQ36123230
Influenza and the challenge for immunologyQ36452600
CD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza.Q36494486
Type I interferon as a stimulus for cross-primingQ37027815
Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levelsQ37106916
Standardization and optimization of multiparameter intracellular cytokine stainingQ37211056
Effects of adjuvants on the safety and immunogenicity of an avian influenza H5N1 vaccine in adultsQ38392346
Vaccine adjuvants alter TCR-based selection thresholds.Q40096549
Multiparameter flow cytometry monitoring of T cell responsesQ40802920
Duration of humoral immunity to common viral and vaccine antigensQ45872621
Antigenically distinct MF59-adjuvanted vaccine to boost immunity to H5N1.Q46325181
Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT systemQ47756393
P433issue3
P921main subjectvaccineQ134808
influenza vaccineQ383260
P304page(s)443-454
P577publication date2010-12-21
P1433published inJournal of Clinical ImmunologyQ6294961
P1476titleH5N1 influenza vaccine formulated with AS03 A induces strong cross-reactive and polyfunctional CD4 T-cell responses
P478volume31

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