Asp2 and Asp3 interact directly with GspB, the export substrate of the Streptococcus gordonii accessory Sec System (scientific article)

Genes in the accessory sec locus of Streptococcus gordonii have three functionally distinct effects on the expression of the platelet-binding protein GspB.

Q44405963

An accessory sec locus of Streptococcus gordonii is required for export of the surface protein GspB and for normal levels of binding to human platelets.

Q45947385

Determinants of the streptococcal surface glycoprotein GspB that facilitate export by the accessory Sec system.

Q45992753

Direct observation of chaperone-induced changes in a protein folding pathway

Q46874460

A unique serine-rich repeat protein (Srr-2) and novel surface antigen (epsilon) associated with a virulent lineage of serotype III Streptococcus agalactiae

Q48095671

Mapping of the Binding Frame for the Chaperone SecB within a Natural Ligand, Galactose-binding Protein

Q54601274

Peptide Binding by Chaperone SecB: Implications for Recognition of Nonnative Structure

Q68208733

Improved vectors for nisin-controlled expression in gram-positive bacteria

Q74241039

Substrate specificity of the SecB chaperone

Q30815173

Investigating the role of secA2 in secretion and glycosylation of a fimbrial adhesin in Streptococcus parasanguis FW213.

Q31095089

A conserved domain of previously unknown function in Gap1 mediates protein-protein interaction and is required for biogenesis of a serine-rich streptococcal adhesin

Q33372901

Glycosylation and biogenesis of a family of serine-rich bacterial adhesins

Q33406850

Role of SraP, a Serine-Rich Surface Protein of Staphylococcus aureus, in binding to human platelets.

Q33769276

Two additional components of the accessory sec system mediating export of the Streptococcus gordonii platelet-binding protein GspB.

Q33788541

Identification of dipeptide repeats and a cell wall sorting signal in the fimbriae-associated adhesin, Fap1, of Streptococcus parasanguis

Q33883470

Transport of preproteins by the accessory Sec system requires a specific domain adjacent to the signal peptide

Q34045689

Asp3 mediates multiple protein-protein interactions within the accessory Sec system of Streptococcus gordonii

Q34222214

Physiological role during export for the retardation of folding by the leader peptide of maltose-binding protein

Q34322460

Binding of the streptococcal surface glycoproteins GspB and Hsa to human salivary proteins

Q34491880

Abundance of the delta subunit of RNA polymerase is linked to the virulence of Streptococcus agalactiae

Q34513660

Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease

Q34975633

The Streptococcus gordonii platelet binding protein GspB undergoes glycosylation independently of export

Q35546776

Two gene determinants are differentially involved in the biogenesis of Fap1 precursors in Streptococcus parasanguis

Q35634711

Glycine residues in the hydrophobic core of the GspB signal sequence route export toward the accessory Sec pathway

Q35879231

Protein targeting by the bacterial twin-arginine translocation (Tat) pathway

Q36085265

Determination of the binding frame within a physiological ligand for the chaperone SecB.

Q36278522

On the role of specific chaperones, the specific ATPase, and the proton motive force in type III secretion.

Q36663477

Characterization of the accessory Sec system of Staphylococcus aureus

Q36898397

Role of the serine-rich surface glycoprotein GspB of Streptococcus gordonii in the pathogenesis of infective endocarditis

Q36952127

A conserved C-terminal 13-amino-acid motif of Gap1 is required for Gap1 function and necessary for the biogenesis of a serine-rich glycoprotein of Streptococcus parasanguinis

Q36974490

Mechanisms of platelet aggregation by viridans group streptococci

Q37021455

Protein translocation across the bacterial cytoplasmic membrane.

Q37031528

A new twist on an old pathway--accessory Sec [corrected] systems

Q37187834

Characterization of Streptococcus gordonii SecA2 as a paralogue of SecA.

Q37191715

Molecular dissection of the secA2 locus of group B Streptococcus reveals that glycosylation of the Srr1 LPXTG protein is required for full virulence

Q37232681

The Streptococcus gordonii surface proteins GspB and Hsa mediate binding to sialylated carbohydrate epitopes on the platelet membrane glycoprotein Ibalpha

Q37582911

Four proteins encoded in the gspB-secY2A2 operon of Streptococcus gordonii mediate the intracellular glycosylation of the platelet-binding protein GspB

Q37583358

SecB--a chaperone dedicated to protein translocation.

Q37710987

Binding of the Streptococcus gordonii surface glycoproteins GspB and Hsa to specific carbohydrate structures on platelet membrane glycoprotein Ibalpha.

Q38320493

A kinetic partitioning model of selective binding of nonnative proteins by the bacterial chaperone SecB.

Q38336960

The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier

Q41848341

Differential Interactions between Tat-specific redox enzyme peptides and their chaperones.

Q43163179

Identification of a twin-arginine leader-binding protein.

Q43579561

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

Streptococcus gordonii

Q7623352

P1104

number of pages

P304

page(s)

3165-3174

P577

publication date

2011-04-29

P1433

published in

Journal of Bacteriology

Q478419

P1476

title

Asp2 and Asp3 interact directly with GspB, the export substrate of the Streptococcus gordonii accessory Sec System

P478

volume

193

Reverse relations

cites work (P2860)

Q36097994	A Specific interaction between SecA2 and a region of the preprotein adjacent to the signal peptide occurs during transport via the accessory Sec system
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Q35598757	Canonical SecA associates with an accessory secretory protein complex involved in biogenesis of a streptococcal serine-rich repeat glycoprotein
Q41551854	Composition and Activity of the Non-canonical Gram-positive SecY2 Complex
Q36581200	Differential localization of the streptococcal accessory sec components and implications for substrate export.
Q36206572	Emerging themes in SecA2-mediated protein export
Q36833053	Gap2 promotes the formation of a stable protein complex required for mature Fap1 biogenesis
Q90258431	Membrane trafficking of the bacterial adhesin GspB and the accessory Sec transport machinery
Q40084923	O-acetylation of the serine-rich repeat glycoprotein GspB is coordinated with accessory Sec transport
Q38159106	Selective transport by SecA2: an expanding family of customized motor proteins
Q58110873	Serine-Rich Repeat Protein adhesins from Lactobacillus reuteri display strain specific glycosylation profiles
Q38827839	The Canonical and Accessory Sec System of Gram-positive Bacteria.
Q64887171	The Two Distinct Types of SecA2-Dependent Export Systems.
Q36280988	The accessory Sec protein Asp2 modulates GlcNAc deposition onto the serine-rich repeat glycoprotein GspB
Q34297837	The sweet tooth of bacteria: common themes in bacterial glycoconjugates.
Q40140255	Three glycosylated serine-rich repeat proteins play a pivotal role in adhesion and colonization of the pioneer commensal bacterium, Streptococcus salivarius.
Q49806509	Unraveling the sequence of cytosolic reactions in the export of GspB adhesin from Streptococcus gordonii.