Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia

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Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0002-9440(10)63759-5
P932PMC publication ID1615781
P698PubMed publication ID15161635

P50authorCory M HogaboamQ61079289
Fernando J MartinezQ89536935
P2093author name stringWilliam D Travis
Raj K Puri
Kevin R Flaherty
Galen B Toews
Thomas V Colby
Bharat H Joshi
Steven L Kunkel
Holly Evanoff
Kristin J Carpenter
Claudia Jakubzick
Esther S Choi
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Two different IL-13 receptor chains are expressed in normal human skin fibroblasts, and IL-4 and IL-13 mediate signal transduction through a common pathwayQ41011905
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Collagen synthesis by human liver (myo)fibroblasts in culture: evidence for a regulatory role of IL-1 beta, IL-4, TGF beta and IFN gammaQ42513635
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IL-4 upregulates tenascin synthesis in scleroderma and healthy skin fibroblastsQ42527575
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IL-13R(alpha)2, a decoy receptor for IL-13 acts as an inhibitor of IL-4-dependent signal transduction in glioblastoma cells.Q42818303
Fibroblasts from idiopathic pulmonary fibrosis and normal lungs differ in growth rate, apoptosis, and tissue inhibitor of metalloproteinases expressionQ43606201
IL-13 fusion cytotoxin ameliorates chronic fungal-induced allergic airway disease in miceQ43803704
Idiopathic pulmonary fibrosis: relationship between histopathologic features and mortalityQ46119457
The interleukin-4/interleukin-13 receptor of human synovial fibroblasts: overexpression of the nonsignaling interleukin-13 receptor alpha2.Q48032045
Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15.Q50113265
Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitroQ50232372
Effects of Th2 cytokines on expression of collagen, MMP-1, and TIMP-1 in conjunctival fibroblasts.Q54797703
Intratumor administration of interleukin 13 receptor-targeted cytotoxin induces apoptotic cell death in human malignant glioma tumor xenografts.Q55473114
Interleukin-4 and interferon-gamma discordantly regulate collagen biosynthesis by functionally distinct lung fibroblast subsetsQ71037699
Targeting of interleukin-13 receptor on human renal cell carcinoma cells by a recombinant chimeric protein composed of interleukin-13 and a truncated form of Pseudomonas exotoxin A (PE38QQR)Q71099789
A novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and interleukin 4Q71921204
Nonspecific interstitial pneumonia/fibrosis. Histologic features and clinical significanceQ72732153
Unusual interleukin-4 and -13 signaling in human normal and tumor lung fibroblastsQ73322473
Altered accessory cell function of alveolar macrophages: a possible mechanism for induction of Th2 secretory profile in idiopathic pulmonary fibrosisQ73337805
Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblastsQ73478890
The interleukin-13 receptor alpha2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathwayQ73784963
IL-4 and IL-13 induce myofibroblastic phenotype of human lung fibroblasts through c-Jun NH2-terminal kinase-dependent pathwayQ73993434
Sensitization of cancer cells to interleukin 13-pseudomonas exotoxin-induced cell death by gene transfer of interleukin 13 receptor alpha chainQ74313373
Histopathologic variability in usual and nonspecific interstitial pneumoniasQ77220427
IL-4 and IL-13 specifically increase adhesion molecule and inflammatory cytokine expression in human lung fibroblastsQ77492715
Th2 cells as effectors in postirradiation pulmonary damage preceding fibrosis in the ratQ77900005
Immunoreactive interleukin 4 and interferon-gamma expression by type II alveolar epithelial cells in interstitial lung diseaseQ77976545
Differential monocyte chemoattractant protein-1 and chemokine receptor 2 expression by murine lung fibroblasts derived from Th1- and Th2-type pulmonary granuloma modelsQ78103035
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectidiopathic interstitial pneumoniaQ1790424
P304page(s)1989-2001
P577publication date2004-06-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleHuman pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia
P478volume164

Reverse relations

cites work (P2860)
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