The translational regulatory function of SecM requires the precise timing of membrane targeting.

scientific article

The translational regulatory function of SecM requires the precise timing of membrane targeting. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1365-2958.2011.07713.X
P932PMC publication ID3134173
P698PubMed publication ID21635582
P5875ResearchGate publication ID51186040

P50authorMee-Ngan F YapQ56926473
P2093author name stringHarris D Bernstein
P2860cites workSecD and SecF are required for the proton electrochemical gradient stimulation of preprotein translocationQ24596484
Structure of a complex of the ATPase SecA and the protein-translocation channelQ27652526
Improved prediction of signal peptides: SignalP 3.0Q27860548
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
Polypeptide Chain Initiation: Nucleotide Sequences of the Three Ribosomal Binding Sites in Bacteriophage R17 RNAQ28252230
The E. coli signal recognition particle is required for the insertion of a subset of inner membrane proteinsQ28302083
Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levelsQ29547813
Signal sequences. The limits of variationQ29616543
Secretion monitor, SecM, undergoes self-translation arrest in the cytosolQ31923120
Domain organization of long signal peptides of single-pass integral membrane proteins reveals multiple functional capacityQ33354073
The native 3D organization of bacterial polysomesQ33402722
Genetic identification of nascent peptides that induce ribosome stallingQ33511404
An unusual signal peptide facilitates late steps in the biogenesis of a bacterial autotransporterQ33715578
Regulation of Escherichia coli secA by cellular protein secretion proficiency requires an intact gene X signal sequence and an active transloconQ33737540
SecM facilitates translocase function of SecA by localizing its biosynthesisQ33848928
Analysis of the Escherichia coli Alp phenotype: heat shock induction in ssrA mutantsQ33885728
The ribosomal exit tunnel functions as a discriminating gateQ34118341
The signal recognition particleQ34275497
Critical regions of secM that control its translation and secretion and promote secretion-specific secA regulationQ34309801
Regulatory nascent peptides in the ribosomal tunnelQ34563139
The targeting pathway of Escherichia coli presecretory and integral membrane proteins is specified by the hydrophobicity of the targeting signalQ34741147
Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY.Q34996061
Characterization of cold-sensitive secY mutants of Escherichia coliQ36192541
The surprising complexity of signal sequencesQ36571413
Protein translocation across the bacterial cytoplasmic membrane.Q37031528
Translocon “Pulling” of Nascent SecM Controls the Duration of Its Translational Pause and Secretion-Responsive secA RegulationQ37051988
The plasticity of a translation arrest motif yields insights into nascent polypeptide recognition inside the ribosome tunnelQ37245890
Delivering proteins for export from the cytosolQ37420386
Translation arrest of SecM is essential for the basal and regulated expression of SecA.Q37483786
Architecture, function and prediction of long signal peptides.Q37522835
Access to ribosomal protein Rpl25p by the signal recognition particle is required for efficient cotranslational translocation.Q39631268
Cotranslational and posttranslational protein translocation in prokaryotic systemsQ39760597
The DsbA signal sequence directs efficient, cotranslational export of passenger proteins to the Escherichia coli periplasm via the signal recognition particle pathwayQ39887818
SRP-dependent co-translational targeting and SecA-dependent translocation analyzed as individual steps in the export of a bacterial proteinQ40388434
Prolyl-tRNA(Pro) in the A-site of SecM-arrested ribosomes inhibits the recruitment of transfer-messenger RNA.Q42640310
Use of thioredoxin as a reporter to identify a subset of Escherichia coli signal sequences that promote signal recognition particle-dependent translocationQ42723141
Basic amino acids in a distinct subset of signal peptides promote interaction with the signal recognition particleQ44569162
Quantitative polysome analysis identifies limitations in bacterial cell-free protein synthesisQ46443261
ΔμH+ and ATP function at different steps of the catalytic cycle of preprotein translocaseQ46481993
An unusual signal peptide extension inhibits the binding of bacterial presecretory proteins to the signal recognition particle, trigger factor, and the SecYEG complexQ46925610
Export of beta-lactamase is independent of the signal recognition particleQ47967258
Signal sequence directs localized secretion of bacterial surface proteins.Q53603429
In vitro analysis of the bacterial twin-arginine-dependent protein export.Q54432409
Translation arrest requires two-way communication between a nascent polypeptide and the ribosome.Q54463767
Genetically encoded but nonpolypeptide prolyl-tRNA functions in the A site for SecM-mediated ribosomal stall.Q54465004
Trigger factor retards protein export in Escherichia coli.Q54538999
Use of in vitro protein synthesis from polymerase chain reaction-generated templates to study interaction of Escherichia coli transcription factors with core RNA polymerase and for epitope mapping of monoclonal antibodiesQ67679637
Translocation of domains of nascent periplasmic proteins across the cytoplasmic membrane is independent of elongationQ70373251
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)540-553
P577publication date2011-06-03
P1433published inMolecular MicrobiologyQ6895967
P1476titleThe translational regulatory function of SecM requires the precise timing of membrane targeting
P478volume81

Reverse relations

cites work (P2860)
Q42944586A biphasic pulling force acts on transmembrane helices during translocon-mediated membrane integration
Q35113643A simple real-time assay for in vitro translation
Q42197968Bacterial lipid modification of proteins requires appropriate secretory signals even for expression - implications for biogenesis and protein engineering
Q42132683Charge-driven dynamics of nascent-chain movement through the SecYEG translocon
Q47215849Identification and characterization of a translation arrest motif in VemP by systematic mutational analysis.
Q61446196Increased freedom of movement in the nascent chain results in dynamic changes in the structure of the SecM arrest motif
Q36970526Mutations in the Escherichia coli ribosomal protein L22 selectively suppress the expression of a secreted bacterial virulence factor.
Q92492317Nascent SecM chain interacts with outer ribosomal surface to stabilize translation arrest
Q42151283Ribosome. Mechanical force releases nascent chain-mediated ribosome arrest in vitro and in vivo
Q47374398The Sec System: Protein Export in Escherichia coli
Q40774135The dynamics of SecM-induced translational stalling
Q34317295Translation initiation rate determines the impact of ribosome stalling on bacterial protein synthesis.

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