Flavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant

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Flavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant is …
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scholarly articleQ13442814

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P356DOI10.1155/2011/385780
P8608Fatcat IDrelease_nvq3dmbfsbbb5ectrr3zzftpkm
P932PMC publication ID3134205
P698PubMed publication ID21765617
P5875ResearchGate publication ID51498849

P50authorBruce P BurnettQ88571070
Lakshmi Pillai-KastooriQ59270697
Alessandra BittoQ85352180
Domenica AltavillaQ85352184
Francesco SquadritoQ87638204
P2093author name stringRobert M Levy
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Flavocoxid, a dual inhibitor of cyclooxygenase and 5-lipoxygenase, blunts pro-inflammatory phenotype activation in endotoxin-stimulated macrophagesQ37395300
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A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammationQ40077624
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Flavocoxid, an anti-inflammatory agent of botanical origin, does not affect coagulation or interact with anticoagulation therapiesQ43015771
GOAL: multicenter, open-label, post-marketing study of flavocoxid, a novel dual pathway inhibitor anti-inflammatory agent of botanical originQ43131558
Flavocoxid counteracts muscle necrosis and improves functional properties in mdx mice: a comparison study with methylprednisolone.Q43270173
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Flavocoxid is as effective as naproxen for managing the signs and symptoms of osteoarthritis of the knee in humans: a short-term randomized, double-blind pilot study.Q45952848
Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.Q46413279
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P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P304page(s)385780
P577publication date2011-06-19
P1433published inMediators of InflammationQ2144494
P1476titleFlavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant
P478volume2011

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cites work (P2860)
Q48220372A dual inhibitor of cyclooxygenase and 5-lipoxygenase protects against kainic acid-induced brain injury
Q43928450Bioguidage search of active compounds from Waltheria indica L. (Malvaceae) used for asthma and inflammation treatment in Burkina Faso
Q26750933Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Therapy-A Hypothesis-Driven Review
Q48194110Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice
Q36252843Effects of flavocoxid, a dual inhibitor of COX and 5-lipoxygenase enzymes, on benign prostatic hyperplasia.
Q41052689Flavocoxid attenuates gentamicin-induced nephrotoxicity in rats.
Q41919479Flavocoxid exerts a potent antiviral effect against hepatitis B virus.
Q41952624Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis
Q38253044Flavocoxid, a nutraceutical approach to blunt inflammatory conditions.
Q38545133Medical Plant Extracts for Treating Knee Osteoarthritis: a Snapshot of Recent Clinical Trials and Their Biological Background
Q35108710Modulation of basophils' degranulation and allergy-related enzymes by monomeric and dimeric naphthoquinones.
Q38558587Nonsteroidal Anti-Inflammatory Therapy: A Journey Toward Safety
Q38450512Proinflammatory Pathways: The Modulation by Flavonoids.

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