Insulin-Like Growth Factor I and the Pathogenesis of Delirium: A Review of Current Evidence

scientific article published on July 3, 2011

Insulin-Like Growth Factor I and the Pathogenesis of Delirium: A Review of Current Evidence is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4061/2011/951403
P953full work available online athttp://downloads.hindawi.com/journals/jar/2011/951403.pdf
http://downloads.hindawi.com/journals/jar/2011/951403.xml
https://downloads.hindawi.com/journals/jar/2011/951403.pdf
https://europepmc.org/articles/PMC3134253
https://europepmc.org/articles/PMC3134253?pdf=render
P932PMC publication ID3134253
P698PubMed publication ID21766035
P5875ResearchGate publication ID51499221

P50authorDimitrios AdamisQ43279412
P2093author name stringDavid Meagher
P2860cites workThe Journal of Clinical Endocrinology and MetabolismQ3186902
Canadian Medical Association JournalQ5030320
Predicting delirium in elderly patients: development and validation of a risk-stratification modelQ71592255
A half-century of delirium research: time to close the gapQ72191502
The occurrence and duration of symptoms in elderly patients with deliriumQ72789896
Serum insulin-like growth factor I in a random population sample of men and women: relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid hormone anQ72792393
Insulin-like growth factor-1 inhibition of apoptosis is associated with increased expression of the bcl-xL gene productQ73106933
Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older womenQ73344551
Psychiatric manifestations accompanying interferon therapy for patients with chronic hepatitis C: An overview of cases in JapanQ73745527
Association of IGF-I levels with muscle strength and mobility in older womenQ74494165
Immunology of delirium: new opportunities for treatment and researchQ74582057
Transcriptional regulation of insulin-like growth factor-I by interferon-gamma requires STAT-5bQ79191173
Frailty and the biochemical effects of recombinant human growth hormone in women after surgery for hip fractureQ79304459
Pre-operative inflammatory markers and the risk of postoperative delirium in elderly patientsQ81280727
More attention, less confusion: time to lessen the burden of deliriumQ83358269
Delirium accelerates cognitive decline in Alzheimer diseaseQ24650202
The Journal of the Association of Physicians of IndiaQ27711389
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axisQ28280037
Serum insulin-like growth factor-1 in centenarians: implications of IGF-1 as a rapid turnover proteinQ32049225
Cerebrospinal fluid cortisol levels are higher in patients with delirium versus controlsQ33533964
Update on the neuropathogenesis of deliriumQ33726603
Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formationQ33744136
Validity of the confusion assessment method in detecting postoperative delirium in the elderly.Q33815073
Actions and interactions of the IGF system in Alzheimer's disease: review and hypothesesQ33884861
Does the insulin-like growth factor system interact with prostaglandins and proinflammatory cytokines during neurodegeneration?Q33899264
Prevalence and detection of delirium in elderly emergency department patientsQ33954884
Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosisQ33959860
Toward a comprehensive neurobiology of IGF-I.Q34100780
Which medications to avoid in people at risk of delirium: a systematic reviewQ34149090
The natural history of delirium in older hospitalized patients: a syndrome of heterogeneityQ52001535
A long-term follow-up study of cerebrospinal fluid somatostatin in deliriumQ52026807
Age-sensitive cognitive function, growth hormone and insulin-like growth factor 1 plasma levels in healthy older men.Q52029699
Delirium. The occurrence and persistence of symptoms among elderly hospitalized patientsQ52045518
Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growthQ52142765
N-terminal tripeptide of IGF-1 (GPE) prevents the loss of TH positive neurons after 6-OHDA induced nigral lesion in ratsQ52170046
Precipitating factors for delirium in hospitalized elderly persons. Predictive model and interrelationship with baseline vulnerabilityQ52308062
Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer typeQ53201609
Abnormalities in adrenal androgens, but not of glucocorticoids, in early Alzheimer's diseaseQ53203458
Decreased plasma insulin-like growth factor-I level in familial Alzheimer's disease patients carrying the Swedish APP 670/671 mutationQ53231343
Protective and rescuing abilities of IGF-I and some putative free radical scavengers against beta-amyloid-inducing toxicity in neurons.Q53232949
The ratio between serum levels of insulin-like growth factor (IGF)-I and the IGF binding proteins (IGFBP-1, 2 and 3) decreases with age in healthy adults and is increased in acromegalic patientsQ57420747
The Prevalence of Dementia in Europe: A Collaborative Study of 1980–1990 FindingsQ57782178
Risk factors and incidence of postoperative delirium in elderly patients after elective and emergency surgeryQ58766619
Growth Factors Rescue Embryonic Dopamine Neurons from Programmed Cell DeathQ59741464
Insulin-Like Growth Factor-I and Cognitive Function in Healthy Older MenQ60038410
Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart StudyQ61663307
Insulin-Like Growth Factor-1 Inhibition of Apoptosis Is Associated with Increased Expression of the bcl-xL Gene ProductQ61774359
IGF1 as predictor of all cause mortality and cardiovascular disease in an elderly populationQ61793914
Insulin-like growth factors and subsequent risk of mortality in the United StatesQ64128401
The relationship between insulin-like growth factor-I, adiposity, and agingQ68812981
Somatomedins in aging and dementia disorders of the Alzheimer typeQ70491373
Delirium and dementia; are they distinct?Q71260846
A cautionary note on the use of the TUNEL stain to determine apoptosisQ71351155
Delirium in acute stroke: a predictor of subsequent cognitive impairment? A two-year follow-up studyQ51013235
Total insulinlike growth factor 1 and insulinlike growth factor binding protein levels, functional status, and mortality in older adultsQ51452772
Serum levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 in healthy centenarians: relationship with plasma leptin and lipid concentrations, insulin action, and cognitive functionQ51574767
Acute confusional states in elderly patients treated for femoral neck fractureQ51771900
Cytokines and IGF-I in delirious and non-delirious acutely ill older medical inpatientsQ51778509
Relationship between cognitive status at admission and incident delirium in older medical inpatientsQ51843753
Ethical research in delirium: arguments for including decisionally incapacitated subjectsQ51871907
APOE and cytokines as biological markers for recovery of prevalent delirium in elderly medical inpatientsQ51908263
Recovery and outcome of delirium in elderly medical inpatientsQ51922042
6 Factors controlling blood concentration of somatomedin CQ40109950
The neuropathogenesis of delirium. A need to focus our researchQ40625700
Effects of growth hormone and insulin-like growth factor I on the immune systemQ40938877
Growth factors improve immediate survival of embryonic dopamine neurons after transplantation into ratsQ41033079
Critically ill patients have high basal growth hormone levels with attenuated oscillatory activity associated with low levels of insulin-like growth factor-I.Q41164502
Regulation of insulin-like growth factor I production in rat C6 glioma cells: possible role as an autocrine/paracrine growth factorQ41624581
Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I geneQ41927570
Acute confusion in elderly medical patientsQ42078551
Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neuronsQ42484843
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neuronsQ42914852
Risk Factors for Delirium in Hospitalized ElderlyQ43498609
Growth hormone replacement in healthy older men improves body composition but not functional abilityQ43506669
Relationships between cortisol, dehydroepiandrosterone sulphate and insulin-like growth factor-I system in dementiaQ43583581
Insulin-like growth factors I and II in healthy man. Estimations of half-lives and production ratesQ43667170
Dexamethasone reduces steady state insulin-like growth factor I messenger ribonucleic acid levels in rat neuronal and glial cells in primary cultureQ43735018
Cytokines and acute phase response in deliriumQ43911607
IGF-I has a direct proliferative effect in adult hippocampal progenitor cellsQ44612681
The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: the Rancho Bernardo StudyQ44723020
Growth hormone dependence of somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II messenger ribonucleic acidsQ44763831
Relationship between baseline insulin-like growth factor-I (IGF-I) and femoral bone density in women aged over 70 years: potential implications for the prevention of age-related bone lossQ44846822
N-terminal tripeptide of IGF-1 improves functional deficits after 6-OHDA lesion in ratsQ44962348
The clinical profile and association of delirium in geriatric patients with hip fractures in a tertiary care hospital in India.Q45216524
Insulin-like growth factor binding protein-3: insulin-like growth factor independence comes of age.Q46695670
The effects of recombinant human insulin-like growth factor-I and growth hormone on body composition in elderly womenQ46972658
Association of insulin-like growth factor-I with body composition, weight history, and past health behaviors in the very old: the Framingham Heart StudyQ47315272
Do guidelines improve the process and outcomes of care in delirium?Q47643402
Serum free IGF-I, total IGF-I, IGFBP-1 and IGFBP-3 levels in an elderly population: relation to age and sex steroid levels.Q47926827
Cognitive changes during growth hormone replacement in adult menQ47998114
Asphyxial brain injury--the role of the IGF systemQ48403241
Serum insulin-like growth factor I regulates brain amyloid-beta levelsQ48454367
Insulin-like Growth Factor-1 (IGF-1) Improves both Neurological Motor and Cognitive Outcome Following Experimental Brain InjuryQ48607091
Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus.Q49084529
Insulin-like growth factor-I and cognitive function in healthy older men.Q49087051
Plasma insulin growth factor-1 and incident delirium in older peopleQ49133122
Cytokine inhibition of JAK-STAT signaling: a new mechanism of growth hormone resistanceQ34368943
Tumor necrosis factor(alpha) and insulin-like growth factor-I in the brain: is the whole greater than the sum of its parts?Q34390682
Use of growth hormone and growth hormone secretagogues in aging: help or harm.Q34401224
Occurrence and outcome of delirium in medical in-patients: a systematic literature reviewQ34519275
The course of delirium in older medical inpatients: a prospective studyQ34742312
Delirium risk factors in elderly hospitalized patientsQ34751734
Mutant mouse models of insulin-like growth factor actions in the central nervous systemQ34930598
Delirium superimposed on dementia: a systematic reviewQ34941448
Potential roles of insulin and IGF-1 in Alzheimer's disease.Q35192493
Capacity, consent, and selection bias in a study of deliriumQ35429196
Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium.Q35431528
Nutrition, insulin, insulin-like growth factors and cancerQ35622485
An approach to drug induced delirium in the elderlyQ35836649
The association between delirium and cognitive decline: a review of the empirical literatureQ35841474
An evaluation of the role of insulin-like growth factors (IGF) and of type-I IGF receptor signalling in hepatocarcinogenesis and in the resistance of hepatocarcinoma cells against drug-induced apoptosisQ35863982
Evidence for a link between IGF-I and cancer.Q35875689
Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity.Q36146984
Regulation of insulin-like growth factor I gene expression by growth hormoneQ36458732
Regulation of muscle mass by growth hormone and IGF-I.Q36736100
Defining normalcy of the somatotropic axis: an attainable goal?Q36780865
Insulin-like growth factor-1 and delirium in critically ill mechanically ventilated patients: a preliminary investigation.Q36845604
Participation in activity and risk for incident deliriumQ36953705
Impaired growth hormone secretion in the adult population: relation to age and adiposityQ36998642
Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signalingQ37135881
Defining delirium for the International Classification of Diseases, 11th RevisionQ37245360
Unravelling the pathophysiology of delirium: a focus on the role of aberrant stress responsesQ37245372
Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}Q37253971
Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammationQ37363276
Delirium and long-term cognitive impairmentQ37393991
Insulin-like growth factor 1 regulates developing brain glucose metabolismQ37438813
Immune modulation of learning, memory, neural plasticity and neurogenesisQ37802555
The informed consent process in older patients who developed delirium: a clinical epidemiologic studyQ39456302
PI3K p110 alpha and p110 beta have differential effects on Akt activation and protection against oxidative stress-induced apoptosis in myoblastsQ39634639
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectdeliriumQ160796
pathogenesisQ372016
P304page(s)951403
P577publication date2011-07-03
P13046publication type of scholarly workreview articleQ7318358
P1433published inJournal of Aging ResearchQ26841941
P1476titleInsulin-like growth factor I and the pathogenesis of delirium: a review of current evidence
Insulin-Like Growth Factor I and the Pathogenesis of Delirium: A Review of Current Evidence
P478volume2011

Reverse relations

cites work (P2860)
Q37682601Delirium and depression: inter-relationship and clinical overlap in elderly people
Q87192348Delirium in the Nursing Home
Q84421018Insulin-like growth factor 1 and delirium
Q36932274Lack of Association between Pre-Operative Insulin-Like Growth Factor-1 and the Risk of Post-Operative Delirium in Elderly Chinese Patients
Q38098921Obstructive sleep apnea and delirium: exploring possible mechanisms
Q57193242Serum insulin-like growth factor 1 (IGF-1) in multiple sclerosis: relation to cognitive impairment and fatigue
Q33996744The Association between IGF-1 Polymorphisms, IGF-1 Serum Levels, and Cognitive Functions in Healthy Adults: The Amsterdam Growth and Health Longitudinal Study
Q38915805The Association of Serum Levels of Brain-Derived Neurotrophic Factor with the Occurrence of and Recovery from Delirium in Older Medical Inpatients.
Q35108416The protocol of the Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial

Search more.