scholarly article | Q13442814 |
P50 | author | Lutz Tautz | Q56501559 |
Maud Vandereyken | Q57005835 | ||
Yotis A Senis | Q60484604 | ||
Johan W.M. Heemskerk | Q68596002 | ||
Tomas Mustelin | Q85072882 | ||
Cécile Oury | Q87613384 | ||
P2093 | author name string | Souad Rahmouni | |
Hongbin Yuan | |||
Marc Thiry | |||
Eduard Sergienko | |||
Patrizio Lancellotti | |||
Thomas D Y Chung | |||
William Guilmain | |||
Johan W M Heemskerk | |||
Ekaterina V Bobkova | |||
Michel Moutschen | |||
Pierre Drion | |||
Johannes A Eble | |||
Emilie Théâtre | |||
Russell Dahl | |||
Christelle Lecut | |||
Alexandre Hego | |||
Lucia Musumeci | |||
Catia V Diogo | |||
Justin Rascon | |||
Karen Gilio | |||
Lisbeth Maurissen | |||
Marijke J Kuijpers | |||
Yalda Mostofi | |||
P2860 | cites work | The mitogen-activated protein kinase phosphatase vaccinia H1-related protein inhibits apoptosis in prostate cancer cells and is overexpressed in prostate cancer | Q24314853 |
Loss of the VHR dual-specific phosphatase causes cell-cycle arrest and senescence | Q24316042 | ||
Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR | Q24316477 | ||
Expression cloning of a human dual-specificity phosphatase | Q24562377 | ||
Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo | Q24669536 | ||
Multidentate Small-Molecule Inhibitors of Vaccinia H1-Related (VHR) Phosphatase Decrease Proliferation of Cervix Cancer Cells | Q27658054 | ||
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings | Q27861111 | ||
Protein tyrosine phosphatases in the human genome | Q28265924 | ||
GPVI and integrin alphaIIb beta3 signaling in platelets | Q28267414 | ||
Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen | Q28364081 | ||
The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis | Q28509969 | ||
Segregation of platelet aggregatory and procoagulant microdomains in thrombus formation: regulation by transient integrin activation | Q30481898 | ||
Inhibition of the Hematopoietic Protein Tyrosine Phosphatase by Phenoxyacetic Acids | Q30499658 | ||
DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase | Q30579145 | ||
Discovery of VHR phosphatase inhibitors with micromolar activity based on structure-based virtual screening | Q33317564 | ||
Roles of platelet STIM1 and Orai1 in glycoprotein VI- and thrombin-dependent procoagulant activity and thrombus formation | Q34025335 | ||
P2X(1)-mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen | Q34150092 | ||
Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype | Q34169675 | ||
Vaccinia H1-related phosphatase is a phosphatase of ErbB receptors and is down-regulated in non-small cell lung cancer | Q34695575 | ||
Global proteomic assessment of the classical protein-tyrosine phosphatome and "Redoxome" | Q35222996 | ||
A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo | Q36370457 | ||
Physical and functional association of the Src family kinases Fyn and Lyn with the collagen receptor glycoprotein VI-Fc receptor gamma chain complex on human platelets | Q36401453 | ||
Regulation of MAP kinases by the VHR dual-specific phosphatase: implications for cell growth and differentiation | Q36609060 | ||
Antiplatelet therapies for the treatment of cardiovascular disease | Q37684794 | ||
Protein tyrosine phosphatases: structure, function, and implication in human disease. | Q38122079 | ||
Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling | Q41976932 | ||
Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets. | Q42582678 | ||
Development of a Vaccinia H1-related (VHR) phosphatase inhibitor with a nonacidic phosphate-mimicking core structure | Q42813512 | ||
Platelet adhesion enhances the glycoprotein VI-dependent procoagulant response: Involvement of p38 MAP kinase and calpain | Q43576470 | ||
Design and synthesis of a dimeric derivative of RK-682 with increased inhibitory activity against VHR, a dual-specificity ERK phosphatase: implications for the molecular mechanism of the inhibition | Q43832835 | ||
4-isoavenaciolide covalently binds and inhibits VHR, a dual-specificity phosphatase. | Q44090503 | ||
Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function. | Q46040273 | ||
Key role of platelet procoagulant activity in tissue factor-and collagen-dependent thrombus formation in arterioles and venules in vivo differential sensitivity to thrombin inhibition | Q46606513 | ||
GPVI-deficient mice lack collagen responses and are protected against experimentally induced pulmonary thromboembolism | Q46684669 | ||
Calcium signalling in platelets and other cells | Q47776811 | ||
Combined in vivo depletion of glycoprotein VI and C-type lectin-like receptor 2 severely compromises hemostasis and abrogates arterial thrombosis in mice. | Q51828070 | ||
The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion | Q52550457 | ||
Identification of a potent inhibitor of human dual-specific phosphatase, VHR, from computer-aided and NMR-based screening to cellular effects. | Q53522193 | ||
Platelet Glycoprotein VI Dimerization, an Active Process Inducing Receptor Competence, Is an Indicator of Platelet Reactivity | Q61866592 | ||
The physiological and pathophysiological roles of platelet CLEC-2 | Q63407979 | ||
The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen | Q63408039 | ||
Platelets activated by collagen through immunoreceptor tyrosine-based activation motif play pivotal role in initiation and generation of neointimal hyperplasia after vascular injury | Q77690015 | ||
CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis | Q84313347 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | thrombosis | Q261327 |
P304 | page(s) | 656-668 | |
P577 | publication date | 2014-12-17 | |
P1433 | published in | Circulation | Q578091 |
P1476 | title | Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis | |
P478 | volume | 131 |
Q90292249 | AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation |
Q92652900 | Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis |
Q41660620 | Critical Roles of Dual-Specificity Phosphatases in Neuronal Proteostasis and Neurological Diseases. |
Q35562905 | DUSP3 Genetic Deletion Confers M2-like Macrophage-Dependent Tolerance to Septic Shock |
Q38651960 | Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration |
Q40077080 | Dual-Specificity Phosphatase 3 Deletion Protects Female, but Not Male, Mice from Endotoxemia-Induced and Polymicrobial-Induced Septic Shock |
Q92495301 | Dual-Specificity Phosphatases in Immunity and Infection: An Update |
Q40579483 | Functional Analysis of Protein Tyrosine Phosphatases in Thrombosis and Hemostasis. |
Q50892082 | Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets. |
Q37386201 | Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release |
Q35671956 | Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy. |
Q58699207 | Revisiting the roles of VHR/DUSP3 phosphatase in human diseases |
Q38372232 | VHR/DUSP3 phosphatase: structure, function and regulation |
Q46419191 | Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release |
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