Bioinformatic prediction and confirmation of beta-adducin as a novel substrate of glycogen synthase kinase 3.

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Bioinformatic prediction and confirmation of beta-adducin as a novel substrate of glycogen synthase kinase 3. is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.251629
P932PMC publication ID3137098
P698PubMed publication ID21606488

P50authorCalum SutherlandQ37834437
Ann M. TurnleyQ42648796
P2093author name stringAdam R Cole
Hovik Farghaian
P2860cites workPhosphoproteomic Analysis of the Mouse Brain Cytosol Reveals a Predominance of Protein Phosphorylation in Regions of Intrinsic Sequence DisorderQ22061729
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Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progressionQ47597706
beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunitsQ48413168
Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's diseaseQ49106755
Inhibition of glycogen synthase kinase 3beta in sensory neurons in culture alters filopodia dynamics and microtubule distribution in growth cones.Q52101333
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A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-cateninQ28115262
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Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating proteinQ34316385
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Axons break in animals lacking beta-spectrinQ36117723
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A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.Q36828945
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Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brainQ39657191
A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylationQ40190612
GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity.Q40470623
Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation eventQ40624453
A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylationQ40795858
Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signalingQ40866028
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Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signallingQ42032355
GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons.Q42141352
Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3betaQ44028713
Convergent evidence for impaired AKT1-GSK3beta signaling in schizophreniaQ44743796
Brain adducin: a protein kinase C substrate that may mediate site-directed assembly at the spectrin-actin junctionQ44822490
Comprehensive mapping of post-translational modifications on synaptic, nuclear, and histone proteins in the adult mouse brainQ44863839
P433issue28
P407language of work or nameEnglishQ1860
P921main subjectbioinformaticsQ128570
P1104number of pages10
P304page(s)25274-25283
P577publication date2011-05-23
P1433published inJournal of Biological ChemistryQ867727
P1476titleBioinformatic prediction and confirmation of beta-adducin as a novel substrate of glycogen synthase kinase 3
P478volume286

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Q90241928Phosphorylation of adducin-1 by cyclin-dependent kinase 5 is important for epidermal growth factor-induced cell migration
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