review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Max Costa | |
Jessica E. Sutherland | |||
P2860 | cites work | Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation | Q22003769 |
Translating the Histone Code | Q22065840 | ||
Crystal structure of the nucleosome core particle at 2.8 A resolution | Q22122355 | ||
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex | Q24324026 | ||
The language of covalent histone modifications | Q27860931 | ||
DNA methyltransferase Dnmt1 associates with histone deacetylase activity | Q28141500 | ||
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex | Q28143627 | ||
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation | Q28143634 | ||
The enigma of arsenic carcinogenesis: role of metabolism | Q28199536 | ||
Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression | Q28379242 | ||
MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin | Q28576622 | ||
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription | Q29547568 | ||
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer | Q29615066 | ||
The role of DNA methylation in mammalian epigenetics | Q29617979 | ||
Genomic imprinting and cancer | Q33545684 | ||
Epigenetics: regulation through repression | Q33751823 | ||
Relationships between chromatin organization and DNA methylation in determining gene expression | Q33765668 | ||
Epigenetic gene silencing in cancer | Q33843160 | ||
Cytosine methylation and human cancer | Q33845225 | ||
Imprinted genes as potential genetic and epigenetic toxicologic targets | Q33852775 | ||
Arsenic: health effects, mechanisms of actions, and research issues | Q33865828 | ||
DNA hypermethylation in tumorigenesis: epigenetics joins genetics | Q33870798 | ||
Mutation hotspots and DNA methylation. | Q33913592 | ||
Mammalian methyltransferases and methyl-CpG-binding domains: proteins involved in DNA methylation | Q33913612 | ||
DNA methylation, genomic imprinting and cancer. | Q33913622 | ||
p53 mutational spectra and the role of methylated CpG sequences | Q33933769 | ||
Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolites | Q33943279 | ||
Both hypomethylation and hypermethylation of DNA associated with arsenite exposure in cultures of human cells identified by methylation-sensitive arbitrarily-primed PCR. | Q34086030 | ||
Epigenetics and DNA methylation come of age in toxicology | Q34124480 | ||
Pharmacokinetics, metabolism, and carcinogenicity of arsenic | Q34236890 | ||
Histone deacetylase as a new target for cancer chemotherapy. | Q34392069 | ||
Histone deacetylase inhibitors as new cancer drugs | Q34416846 | ||
Altered DNA methylation: a secondary mechanism involved in carcinogenesis | Q34504084 | ||
Histone deacetylases and cancer: causes and therapies | Q34570082 | ||
DNA hypomethylation leads to elevated mutation rates | Q34752442 | ||
Metal mutagenesis in transgenic Chinese hamster cell lines | Q35032343 | ||
Toxicity, uptake, and mutagenicity of particulate and soluble nickel compounds | Q35032351 | ||
The 5-methylcytosine content of DNA from human tumors | Q35689206 | ||
Cytosine methylation determines hot spots of DNA damage in the human P53 gene | Q36106985 | ||
Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens | Q36550875 | ||
Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression | Q36928327 | ||
Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A. | Q40623681 | ||
Association of c-myc overexpression and hyperproliferation with arsenite-induced malignant transformation | Q40780343 | ||
The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells | Q40790280 | ||
Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon | Q40838381 | ||
Effects of DNA methylation on DNA-binding proteins and gene expression. | Q40912883 | ||
Nickel enhances telomeric silencing in Saccharomyces cerevisiae | Q40959679 | ||
Nickel subsulfide is genotoxic in vitro but shows no mutagenic potential in respiratory tract tissues of BigBlue rats and Muta Mouse mice in vivo after inhalation | Q40990788 | ||
Neoplastic transformation of cells by soluble but not particulate forms of metals used in orthopaedic implants | Q41025673 | ||
A possible function of constitutive heterochromatin: the bodyguard hypothesis | Q41070071 | ||
Transgenic Chinese hamster V79 cell lines which exhibit variable levels of gpt mutagenesis | Q41205633 | ||
Oncogenic mechanisms mediated by DNA methylation | Q41492393 | ||
Mutagenic responses of nickel oxides and nickel sulfides in Chinese hamster V79 cell lines at the xanthine-guanidine phosphoribosyl transferase locus | Q41552519 | ||
Mutagenicity of soluble and insoluble nickel compounds at the gpt locus in G12 Chinese hamster cells | Q41579762 | ||
Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control | Q41695392 | ||
DNA methylation as a target for drug design | Q41730013 | ||
Nickel carcinogenesis, mutation, epigenetics, or selection | Q43198047 | ||
Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report | Q43775906 | ||
Morphological and neoplastic transformation of C3H/10T1/2 Cl 8 mouse embryo cells by insoluble carcinogenic nickel compounds | Q44136906 | ||
Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: a model for a mechanism of carcinogenesis | Q48049008 | ||
Behind the scenes of gene expression. | Q52131201 | ||
Gene silencing by methyl-CpG-binding proteins. | Q52187462 | ||
Ni(II) specifically cleaves the C-terminal tail of the major variant of histone H2A and forms an oxidative damage-mediating complex with the cleaved-off octapeptide. | Q53407848 | ||
Interactions of Nickel(II) with histones: interactions of Nickel(II) with CH3CO-Thr-Glu-Ser-His-His-Lys-NH2, a peptide modeling the potential metal binding site in the "C-Tail" region of histone H2A. | Q53430575 | ||
DNA-protein cross-links induced by nickel compounds in intact cultured mammalian cells. | Q53542059 | ||
Sequential events in the induction of transformation in cell culture by specific nickel compounds. | Q53558410 | ||
Factors influencing the phagocytosis, neoplastic transformation, and cytotoxicity of particulate nickel compounds in tissue culture systems. | Q53569937 | ||
Carcinogenic activity of particulate nickel compounds is proportional to their cellular uptake. | Q53576264 | ||
Antagonistic effect of magnesium chloride on the nickel chloride-induced inhibition of DNA replication in Chinese hamster ovary cells | Q68114375 | ||
Pathway of nickel uptake influences its interaction with heterochromatic DNA | Q69531799 | ||
Methylation of reiterated sequences in mammalian DNAs Effects of the tissue type, age, malignancy and hormonal induction | Q70754158 | ||
Interactions of nickel(II) with histones: enhancement of 2'-deoxyguanosine oxidation by Ni(II) complexes with CH3CO-Cys-Ala-Ile-His-NH2, a putative metal binding sequence of histone H3 | Q71610180 | ||
Interaction of Ni(II) and Cu(II) with a metal binding sequence of histone H4: AKRHRK, a model of the H4 tail | Q73835580 | ||
Interaction of Nickel(II) with histones: in vitro binding of nickel(II) to the core histone tetramer | Q77222637 | ||
Genomic imprinting and cancer | Q77785927 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | epigenetics | Q26939 |
history and philosophy of science | Q5774812 | ||
P304 | page(s) | 151-160 | |
P577 | publication date | 2003-03-01 | |
P1433 | published in | Annals of the New York Academy of Sciences | Q2431664 |
P1476 | title | Epigenetics and the environment | |
Epigenetics and the Environment | |||
P478 | volume | 983 |
Q50799531 | A multi-tissue analysis identifies HLA complex group 9 gene methylation differences in bipolar disorder |
Q24297869 | A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription |
Q34396522 | A review on the evidence of transgenerational transmission of posttraumatic stress disorder vulnerability |
Q41553016 | Acetylation- and Methylation-Related Epigenetic Proteins in the Context of Their Targets |
Q35800389 | Adolescent idiopathic scoliosis (AIS), environment, exposome and epigenetics: a molecular perspective of postnatal normal spinal growth and the etiopathogenesis of AIS with consideration of a network approach and possible implications for medical th |
Q34445785 | Air pollution and cancer: biomarker studies in human populations |
Q37402757 | Beyond genetics: epigenetic code in chronic kidney disease |
Q36311595 | Carcinogenic effect of nickel compounds |
Q47181318 | Changes in DNA methylation induced by multi-walled carbon nanotube exposure in the workplace. |
Q45001829 | Could monitoring methylation markers aid the management of schizophrenia? |
Q36725766 | Cytostatic drug treatment causes seeding of gene promoter methylation |
Q30497576 | DNA methylation patterns provide insight into epigenetic regulation in the Pacific oyster (Crassostrea gigas) |
Q37668895 | DNA methylation profile associated with rapid decline in kidney function: findings from the CRIC study |
Q34261777 | DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth |
Q47447012 | Derivation of PM10 size-selected human equivalent concentrations of inhaled nickel based on cancer and non-cancer effects on the respiratory tract |
Q37424434 | Discovering how environmental exposures alter genes could lead to new treatments for chronic illnesses. |
Q25256850 | Distinct gene expression profiles in immortalized human urothelial cells exposed to inorganic arsenite and its methylated trivalent metabolites |
Q55007013 | Downregulation of histone demethylase JMJD1C inhibits colorectal cancer metastasis through targeting ATF2. |
Q34157414 | Drugs and addiction: an introduction to epigenetics. |
Q41902392 | Dynamic usage of transcription start sites within core promoters |
Q38876530 | Epigenetic Mechanisms as an Interface Between the Environment and Genome |
Q35237163 | Epigenetic approaches to psychiatric disorders |
Q26864455 | Epigenetic epidemiology: promises for public health research |
Q24652697 | Epigenetic mediation of environmental influences in major psychotic disorders |
Q37984019 | Epigenetic targets of some toxicologically relevant metals: a review of the literature |
Q39159164 | Epigenetics and Health Disparities. |
Q28768502 | Epigenetics and human disease: translating basic biology into clinical applications |
Q92554953 | Epigenetics recording varied environment and complex cell events represents the origin of cellular aging |
Q26783880 | Epigenetics: linking social and environmental exposures to preterm birth |
Q34051535 | Epigenome Mapping in Normal and Disease States |
Q34582324 | Estimation of CpG coverage in whole methylome next-generation sequencing studies |
Q33703623 | Extreme methylation values of imprinted genes in human abortions and stillbirths |
Q37658736 | Gene regulation and molecular toxicology |
Q36620018 | Genetic and environmental influences on nutrient intake |
Q35551099 | Genetic and epigenetic alterations as hallmarks of the intricate road to cancer. |
Q28255368 | Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium |
Q30478587 | Genetics of anxiety and trauma-related disorders |
Q35024282 | Genome-scale approaches to the epigenetics of common human disease |
Q35678124 | Global DNA methylation in old subjects is correlated with frailty. |
Q37089523 | High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot |
Q33719361 | Identification of genetic and epigenetic marks involved in population structure |
Q33624356 | Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer |
Q28080829 | Influence of toxicologically relevant metals on human epigenetic regulation |
Q42651794 | Isolation and characterization of a novel noncoding RNA from nickel-induced lung cancer |
Q92155978 | Leveraging Epidemiology to Improve Risk Assessment |
Q37581443 | MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case--control samples |
Q64242812 | Metal nickel exposure increase the risk of congenital heart defects occurrence in offspring: A case-control study in China |
Q37787464 | Methods: Genetic Epidemiology |
Q34604581 | MethylPCA: a toolkit to control for confounders in methylome-wide association studies |
Q57697822 | Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples |
Q35090701 | Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults |
Q34309924 | MicroRNA-152 targets DNA methyltransferase 1 in NiS-transformed cells via a feedback mechanism |
Q36786517 | Molecular studies of major depressive disorder: the epigenetic perspective |
Q35897276 | Monozygotic twins discordant for constitutive BRCA1 promoter methylation, childhood cancer and secondary cancer |
Q37098453 | Nasal epithelial cells as surrogates for bronchial epithelial cells in airway inflammation studies |
Q38124892 | Nickel alloys in the oral environment |
Q52661240 | Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1. |
Q36589155 | Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profiling |
Q47972459 | Parental vitamin D deficiency during pregnancy is associated with increased blood pressure in offspring via Panx1 hypermethylation. |
Q38210476 | Personalized medicine and type 2 diabetes: lesson from epigenetics. |
Q37738083 | Pharmacoepigenetics in heart failure |
Q36088914 | Phenotypic differences in genetically identical organisms: the epigenetic perspective. |
Q29614515 | Phenotypic plasticity and the epigenetics of human disease |
Q41679957 | Phosphorylation of H3S10 blocks the access of H3K9 by specific antibodies and histone methyltransferase. Implication in regulating chromatin dynamics and epigenetic inheritance during mitosis |
Q39848013 | Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD. |
Q30857458 | Refinement of schizophrenia GWAS loci using methylome-wide association data |
Q38809006 | Review: DNA methylation and alcohol use disorders: Progress and challenges |
Q42822281 | Ribonucleosidelabeling with Os(vi): A methodological approach to evaluation of RNA methylation by HPLC-ICP-MS |
Q40052749 | Sodium arsenite modulates histone acetylation, histone deacetylase activity and HMGN protein dynamics in human cells |
Q37020205 | Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation |
Q33959408 | Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns. |
Q37524743 | Testing two models describing how methylome-wide studies in blood are informative for psychiatric conditions |
Q35500732 | The burden of cancer risk in Canada's indigenous population: a comparative study of known risks in a Canadian region |
Q34555647 | The ghost in our genes: legal and ethical implications of epigenetics. |
Q35182046 | The identification of specific methylation patterns across different cancers |
Q35227826 | The periconceptional environment and cardiovascular disease: does in vitro embryo culture and transfer influence cardiovascular development and health? |
Q33937848 | The relevance of epigenetics to PTSD: implications for the DSM-V |
Q37912098 | The urban brain: new directions in research exploring the relation between cities and mood-anxiety disorders. |
Q22251017 | Transcriptional and epigenetic mechanisms of addiction |
Q37013617 | Transgenerational transmission of cortisol and PTSD risk |
Q37082648 | Validation of differential GDAP1 DNA methylation in alcohol dependence and its potential function as a biomarker for disease severity and therapy outcome |
Q38097131 | Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases? |
Search more.