Epigenetic Changes: Potential Therapeutic Targets

scientific article published on March 1, 2003

Epigenetic Changes: Potential Therapeutic Targets is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/J.1749-6632.2003.TB05982.X
P953full work available at URLhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1749-6632.2003.tb05982.x
https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1749-6632.2003.tb05982.x
P698PubMed publication ID12724232

P2093author name stringThea Kalebic
P2860cites workCloning and functional characterization of HDAC11, a novel member of the human histone deacetylase familyQ24294179
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promotersQ28140428
DNA methyltransferase Dnmt1 associates with histone deacetylase activityQ28141500
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Retinoblastoma protein represses transcription by recruiting a histone deacetylaseQ28262155
Rb interacts with histone deacetylase to repress transcriptionQ28263985
Methylation mattersQ28364163
Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistanceQ28378687
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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancerQ29615066
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Low-dose 5-aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patientsQ33891633
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p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cellsQ36489810
MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3)Q36556977
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A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancerQ40954602
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Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case reportQ43775906
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Apoptosis in colorectal tumour cells: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate.Q54182323
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancersQ55480673
The EORTC Early Clinical Trials Cooperative Group experience with 5-aza-2'-deoxycytidine (NSC 127716) in patients with colo-rectal, head and neck, renal carcinomas and malignant melanomasQ69018368
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Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancersQ71729088
Aberrant methylation of gene promoters in cancer---concepts, misconcepts, and promiseQ74339007
P407language of work or nameEnglishQ1860
P921main subjecthistory and philosophy of scienceQ5774812
P304page(s)278-285
P577publication date2003-03-01
P1433published inAnnals of the New York Academy of SciencesQ2431664
P1476titleEpigenetic changes: potential therapeutic targets
Epigenetic Changes: Potential Therapeutic Targets
P478volume983

Reverse relations

cites work (P2860)
Q38161335Cumulative Epigenetic Abnormalities in Host Genes with Viral and Microbial Infection during Initiation and Progression of Malignant Lymphoma/Leukemia
Q41209870EpiDBase: a manually curated database for small molecule modulators of epigenetic landscape
Q48944595Expression of cell growth negative regulators MEG3 and GADD45γ is lost in most sporadic human pituitary adenomas
Q35551099Genetic and epigenetic alterations as hallmarks of the intricate road to cancer.
Q40399331Genetic and epigenetic alterations of RB2/p130 tumor suppressor gene in human sporadic retinoblastoma: implications for pathogenesis and therapeutic approach
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Q45088582Insulin-like growth factor binding protein-3 (IGFBP-3) plays a role in the anti-tumorigenic effects of 5-Aza-2'-deoxycytidine (AZA) in breast cancer cells.
Q34189725Maintenance of a functional higher order chromatin structure: The role of the nuclear matrix in normal and disease states.
Q41786430Multi-step aberrant CpG island hyper-methylation is associated with the progression of adult T-cell leukemia/lymphoma
Q37962579Novel DNA binding domain-based assays for detection of methylated and nonmethylated DNA.
Q40258606Rapid and sensitive detection of CpG-methylation using methyl-binding (MB)-PCR.
Q53664696Tumor-specific exon 1 mutations could be the 'hit event' predisposing Rb2/p130 gene to epigenetic silencing in lung cancer.

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