Plasminogen activator inhibitor-type I gene deficient mice show reduced influx of neutrophils in ventilator-induced lung injury

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Plasminogen activator inhibitor-type I gene deficient mice show reduced influx of neutrophils in ventilator-induced lung injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2011/217896
P932PMC publication ID3140778
P698PubMed publication ID21789277
P5875ResearchGate publication ID51521317

P50authorJoris Jth RoelofsQ42382057
Nicole P JuffermansQ88062370
Marcus J SchultzQ94471977
P2093author name stringJorrit-Jan H Hofstra
Alexander P J Vlaar
Vivian de Waard
Esther K Wolthuis
P2860cites workPlasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumoniaQ24306456
Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in miceQ24310475
Analysis of blood coagulation in mice: pre-analytical conditions and evaluation of a home-made assay for thrombin-antithrombin complexesQ24815046
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome NetworkQ27861021
Systemic inhibition of the angiotensin-converting enzyme limits lipopolysaccharide-induced lung neutrophil recruitment through both bradykinin and angiotensin II-regulated pathwaysQ28506961
Inhibition of matrix metalloproteinase-9 prevents neutrophilic inflammation in ventilator-induced lung injuryQ28565915
The acute respiratory distress syndromeQ29615140
4G/5G polymorphism of plasminogen activator inhibitor-1 gene is associated with mortality in intensive care unit patients with severe pneumoniaQ34022566
The plasminogen activator/plasmin systemQ34202297
New functions of stromal proteases and their inhibitors in tumor progressionQ34267663
From evidence to clinical practice: effective implementation of therapeutic hypothermia to improve patient outcome after cardiac arrestQ34528902
Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injuryQ34816925
Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumoniaQ35536493
Sepsis and disseminated intravascular coagulationQ35647766
Transepithelial migration of neutrophils: mechanisms and implications for acute lung injuryQ37180272
Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 geneQ37351382
Plasminogen activator inhibitor-1 in acute hyperoxic mouse lung injuryQ37362031
Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysisQ40305997
Regulation of lipopolysaccharide-induced lung inflammation by plasminogen activator Inhibitor-1 through a JNK-mediated pathwayQ40376244
Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infectionQ40867377
Plasminogen activator inhibitor-1 is a significant determinant of renal injury in experimental crescentic glomerulonephritisQ42441652
Ventilator-induced endothelial activation and inflammation in the lung and distal organsQ42930040
Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy miceQ43120915
Procoagulant and fibrinolytic activity in ventilator-associated pneumonia: impact of inadequate antimicrobial therapyQ43522029
Development and disease in proteinase-deficient mice: role of the plasminogen, matrix metalloproteinase and coagulation systemQ45889584
Increased plasminogen activator inhibitor-1 concentrations in bronchoalveolar lavage fluids are associated with increased mortality in a cohort of patients with Pseudomonas aeruginosaQ46581710
Alveolar fibrinolytic capacity suppressed by injurious mechanical ventilation.Q47835857
Mechanisms of early pulmonary neutrophil sequestration in ventilator-induced lung injury in miceQ47955046
Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injuryQ48659724
Mechanical ventilation affects alveolar fibrinolysis in LPS-induced lung injury.Q50078974
Role for nuclear factor-kappaB in augmented lung injury because of interaction between hyperoxia and high stretch ventilationQ50449872
Neutrophil elastase inhibitor (sivelestat) attenuates subsequent ventilator-induced lung injury in mice.Q50967343
Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia.Q51723107
Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.Q54416579
Alveolar Fibrin Formation Caused by Enhanced Procoagulant and Depressed Fibrinolytic Capacities in Severe PneumoniaQ60364295
Neutrophil-mediated pulmonary vascular injury. Synergistic effect of trace amounts of lipopolysaccharide and neutrophil stimuli on vascular permeability and neutrophil sequestration in the lungQ68168256
Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicalsQ70328897
Prognostic impact of urokinase, urokinase receptor, and type 1 plasminogen activator inhibitor in squamous and large cell lung cancer tissueQ72132774
Urokinase (uPA) and PAI-1 predict survival in advanced ovarian cancer patients (FIGO III) after radical surgery and platinum-based chemotherapyQ72462027
Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injuryQ73186268
Ventilator-induced lung injury is associated with neutrophil infiltration, macrophage activation, and TGF-beta 1 mRNA upregulation in rat lungsQ73399613
Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndromeQ73935099
Attenuation of ventilator-induced acute lung injury in an animal model by inhibition of neutrophil adhesion by leumedins (NPC 15669)Q74318686
Contrasting post-traumatic serial changes for D-dimer and PAI-1 in critically injured patientsQ77747912
Plasminogen activator inhibitor type-1 deficiency attenuates murine antigen-induced arthritisQ77749263
Plasminogen activator inhibitor 1 and vitronectin protect against stenosis in a murine carotid artery ligation modelQ78664253
The response to recruitment worsens with progression of lung injury and fibrin accumulation in a mouse model of acid aspirationQ79917809
Recombinant human soluble tumor necrosis factor-alpha receptor fusion protein partly attenuates ventilator-induced lung injuryQ81691337
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectventilatorQ813243
pulmonary injuryQ7259546
P304page(s)217896
P577publication date2011-07-14
P1433published inCritical Care Research and PracticeQ26842063
P1476titlePlasminogen activator inhibitor-type I gene deficient mice show reduced influx of neutrophils in ventilator-induced lung injury
P478volume2011

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cites work (P2860)
Q41167873Effects of Zinc Finger Protein A20 on Lipopolysaccharide (LPS)-Induced Pulmonary Inflammation/Anti-Inflammatory Mediators in an Acute Lung Injury/Acute Respiratory Distress Syndrome Rat Model.
Q36221698In vivo evidence for an endothelium-dependent mechanism in radiation-induced normal tissue injury
Q91755828Plasma Cold-Inducible RNA-Binding Protein Predicts Lung Dysfunction After Cardiovascular Surgery Following Cardiopulmonary Bypass: A Prospective Observational Study
Q37286847Plasminogen activator inhibitor-1 does not contribute to the pulmonary pathology induced by acute exposure to ozone

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