Energy status and HIF signalling in chorionic villi show no evidence of hypoxic stress during human early placental development

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Energy status and HIF signalling in chorionic villi show no evidence of hypoxic stress during human early placental development is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/MOLEHR/GAU105
P932PMC publication ID4339857
P698PubMed publication ID25391298
P5875ResearchGate publication ID268232877

P50authorSteve Charnock-JoneQ57177791
P2093author name stringL Gardner
E Jauniaux
G J Burton
T Cindrova-Davies
M Tissot van Patot
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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensingQ24291102
A conserved family of prolyl-4-hydroxylases that modify HIFQ24291794
Placental apoptosis in normal human pregnancyQ59367743
Dynamic HIF1A Regulation During Human Placental Development1Q61777030
Effect of functional grade and etiology on in vivo hepatic phosphorus-31 magnetic resonance spectroscopy in cirrhosis: biochemical basis of spectral appearancesQ72511278
Changes in proliferative potential, apoptosis and Bcl-2 protein expression in cytotrophoblasts and syncytiotrophoblast in human placenta over the course of pregnancyQ73090296
Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placentaQ74036461
Telomerase activity in gestational trophoblastic disease and placental tissue from early and late human pregnanciesQ77578762
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tensionQ24307473
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1Q24316075
IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesisQ24320080
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1Q24320257
Endometrial glands as a source of nutrients, growth factors and cytokines during the first trimester of human pregnancy: a morphological and immunohistochemical studyQ24795515
Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1Q28141355
HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleusQ28191456
Uterine glands provide histiotrophic nutrition for the human fetus during the first trimester of pregnancyQ28202751
Regulation of creatine kinase isoenzymes in human placenta during early, mid-, and late gestationQ28297157
The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in miceQ28591832
Uterine Glands Provide Histiotrophic Nutrition for the Human Fetus during the First Trimester of PregnancyQ29303420
Human placental metabolic adaptation to chronic hypoxia, high altitude: hypoxic preconditioningQ33589496
Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy: the Boyd collection revisitedQ33732595
Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy.Q33894600
Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3)Q33939664
The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.Q35036600
Trophoblastic oxidative stress and the release of cell-free feto-placental DNA.Q35221979
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Trophoblastic oxidative stress in relation to temporal and regional differences in maternal placental blood flow in normal and abnormal early pregnanciesQ35748884
Nuclear factor-kappa B, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: effects of antioxidantQ35757165
Onset of maternal arterial blood flow and placental oxidative stress. A possible factor in human early pregnancy failureQ35829649
Placental oxidative stress: from miscarriage to preeclampsiaQ35879133
Oxidative stress, gene expression, and protein changes induced in the human placenta during laborQ36007397
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Hypoxia tolerance in animals: biology and application.Q37766604
Functional regulation of HIF-1α under normoxia--is there more than post-translational regulation?Q37866715
Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor kappa B activationQ40683794
Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha proteinQ44253539
Histological study of the materno-embryonic interface in spontaneous abortionQ44283098
Metabolite concentrations in human term placentae and their changes due to delayed collection after deliveryQ44302008
Polyol concentrations in the fluid compartments of the human conceptus during the first trimester of pregnancy: maintenance of redox potential in a low oxygen environmentQ45161382
Human cytotrophoblast expression of the von Hippel-Lindau protein is downregulated during uterine invasion in situ and upregulated by hypoxia in vitro.Q46000914
Gabor Than Award Lecture 2008: pre-eclampsia - from placental oxidative stress to maternal endothelial dysfunctionQ46334762
In vivo ³¹P-MR spectroscopy in normal pregnancy, early and late preeclampsia: a study of placental metabolism.Q50802237
Quantitative analysis of liver metabolites in three stages of the circannual hibernation cycle in 13-lined ground squirrels by NMR.Q51102221
P433issue3
P921main subjecthypoxiaQ105688
P304page(s)296-308
P577publication date2014-11-11
P1433published inMolecular Human ReproductionQ15761794
P1476titleEnergy status and HIF signalling in chorionic villi show no evidence of hypoxic stress during human early placental development
P478volume21

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cites work (P2860)
Q36357099Biomarker development for presymptomatic molecular diagnosis of preeclampsia: feasible, useful or even unnecessary?
Q50152159Decreased ATP production and myocardial contractile reserve in metabolic heart disease.
Q53690390Development of the Human Placenta and Fetal Heart: Synergic or Independent?
Q42367742Enhanced HIF2α expression during human trophoblast differentiation into syncytiotrophoblast suppresses transcription of placental growth factor
Q56517024Evidence of oxidative stress-induced senescence in mature, post-mature and pathological human placentas
Q46638900Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult.
Q92723749Metabolomic Investigation of β-Thalassemia in Chorionic Villi Samples
Q30245567Placental Origins of Chronic Disease
Q36770326Placental hypoxia, endoplasmic reticulum stress and maternal endothelial sensitisation by sFLT1 in pre-eclampsia
Q91815900Pre-eclampsia: pathogenesis, novel diagnostics and therapies

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