scholarly article | Q13442814 |
P50 | author | Pascale Marchot | Q28324823 |
Ludovic Renault | Q42846004 | ||
P2093 | author name string | Yves Bourne | |
P2860 | cites work | [Acetylcholinesterase from snake venoms] | Q73693989 |
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Substrate binding to the peripheral site of acetylcholinesterase initiates enzymatic catalysis. Substrate inhibition arises as a secondary effect | Q77800763 | ||
Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding | Q79892396 | ||
Structural insights into AChE inhibition by monoclonal antibodies | Q82337563 | ||
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system | Q22066255 | ||
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Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase | Q24561371 | ||
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids | Q24684673 | ||
A new and rapid colorimetric determination of acetylcholinesterase activity | Q26778487 | ||
Three-dimensional structures ofDrosophila melanogasteracetylcholinesterase and of its complexes with two potent inhibitors | Q27625349 | ||
Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II | Q27627732 | ||
Structure of a complex of the potent and specific inhibitor BW284C51 with Torpedo californica acetylcholinesterase | Q27639706 | ||
Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site | Q27640254 | ||
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation | Q27643075 | ||
Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation | Q27660694 | ||
Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations | Q27667894 | ||
Molecular characterization of monoclonal antibodies that inhibit acetylcholinesterase by targeting the peripheral site and backdoor region | Q27680420 | ||
Structures of human acetylcholinesterase in complex with pharmacologically important ligands | Q27682655 | ||
Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase | Q27684632 | ||
Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex | Q27732191 | ||
Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target | Q27733273 | ||
Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly | Q27766719 | ||
Inference of macromolecular assemblies from crystalline state | Q27860457 | ||
Coot: model-building tools for molecular graphics | Q27860505 | ||
HADDOCK: a protein-protein docking approach based on biochemical or biophysical information | Q27860814 | ||
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The CCP4 suite: programs for protein crystallography | Q27861090 | ||
The cholinesterases: from genes to proteins | Q28245653 | ||
Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein | Q28247386 | ||
Molecular and cellular biology of cholinesterases | Q28260121 | ||
Interaction of fluorescence probes with acetylcholinesterase. Site and specificity of propidium binding | Q28337937 | ||
CAVER 3.0: a tool for the analysis of transport pathways in dynamic protein structures | Q28484476 | ||
Identification of a novel mouse membrane-bound family 1 glycosidase-like protein, which carries an atypical active site structure | Q28589723 | ||
ElNemo: a normal mode web server for protein movement analysis and the generation of templates for molecular replacement | Q29618046 | ||
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Acetylcholinesterase from snake venom as a model for its nerve and muscle counterpart. | Q33689334 | ||
cDNA sequences of Torpedo marmorata acetylcholinesterase: primary structure of the precursor of a catalytic subunit; existence of multiple 5'-untranslated regions | Q33929278 | ||
An electrostatic mechanism for substrate guidance down the aromatic gorge of acetylcholinesterase | Q34366186 | ||
Long route or shortcut? A molecular dynamics study of traffic of thiocholine within the active-site gorge of acetylcholinesterase | Q34398608 | ||
Cloning and expression of acetylcholinesterase from Electrophorus. Splicing pattern of the 3' exons in vivo and in transfected mammalian cells | Q34450245 | ||
The origin of the molecular diversity and functional anchoring of cholinesterases | Q34759065 | ||
Molecular cloning of mouse acetylcholinesterase: tissue distribution of alternatively spliced mRNA species | Q34978467 | ||
Cloning and expression of acetylcholinesterase from Bungarus fasciatus venom. A new type of cooh-terminal domain; involvement of a positively charged residue in the peripheral site | Q36802894 | ||
Acetylcholinesterase: how is structure related to function? | Q37202189 | ||
The gates of ion channels and enzymes | Q37635486 | ||
Purification and characterization of acetylcholinesterase from desert cobra (Walterinnesia aegyptia) venom | Q38979326 | ||
Acetylcholinesterase from Bungarus fasciatus venom—I. Substrate specificity | Q40347424 | ||
Acetylcholinesterase from Bungarus fasciatus venom—II. Effects of pH and temperature | Q40347428 | ||
Allosteric Control of Acetylcholinesterase Catalysis by Fasciculin | Q41302137 | ||
Structural insights into substrate traffic and inhibition in acetylcholinesterase | Q41444745 | ||
Site of fasciculin interaction with acetylcholinesterase | Q41474134 | ||
Cobra Venom Acetylcholinesterase. Purification and Molecular Properties | Q41679912 | ||
Electrooptical measurements demonstrate a large permanent dipole moment associated with acetylcholinesterase | Q41861380 | ||
Electron microscopic studies of acetylcholinesterase from Bungarus fasciatus venom | Q43805821 | ||
Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite | Q43923934 | ||
Inhibitors tethered near the acetylcholinesterase active site serve as molecular rulers of the peripheral and acylation sites | Q44506930 | ||
Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors | Q46263827 | ||
Role of the peripheral anionic site on acetylcholinesterase: inhibition by substrates and coumarin derivatives | Q46724847 | ||
Proteomic analysis of Moroccan cobra Naja haje legionis venom using tandem mass spectrometry | Q46968167 | ||
Binding of 125I-fasciculin to rat brain acetylcholinesterase. The complex still binds diisopropyl fluorophosphate | Q48266569 | ||
The binding sites of inhibitory monoclonal antibodies on acetylcholinesterase. Identification of a novel regulatory site at the putative "back door". | Q48909381 | ||
Insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel. | Q52690659 | ||
Conformational flexibility in the peripheral site of Torpedo californica acetylcholinesterase revealed by the complex structure with a bifunctional inhibitor. | Q53276945 | ||
Open "back door" in a molecular dynamics simulation of acetylcholinesterase. | Q54032280 | ||
Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states | Q56602329 | ||
The acetylcholinesterase of Bungarus fasciatus venom | Q67247094 | ||
Affinity chromatography of acetylcholinesterase. The importance of hydrophobic interactions | Q67833141 | ||
Acetylcholinesterase from Bungarus venom: a monomeric species | Q71171809 | ||
Characterization of Monoclonal Antibodies that Strongly Inhibit Electrophorus Electricus Acetylcholinesterase | Q71994354 | ||
Fasciculin 2 Binds to the Peripheral Site on Acetylcholinesterase and Inhibits Substrate Hydrolysis by Slowing a Step Involving Proton Transfer during Enzyme Acylation | Q71996658 | ||
The "back door" hypothesis for product clearance in acetylcholinesterase challenged by site-directed mutagenesis | Q72808598 | ||
Acetylcholinesterases from Elapidae snake venoms: biochemical, immunological and enzymatic characterization | Q73424853 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | snake venom | Q424200 |
P304 | page(s) | 1522-1535 | |
P577 | publication date | 2014-11-19 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Crystal structure of snake venom acetylcholinesterase in complex with inhibitory antibody fragment Fab410 bound at the peripheral site: evidence for open and closed states of a back door channel | |
P478 | volume | 290 |
Q90190303 | A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides |
Q38630724 | Computational Studies on Acetylcholinesterases. |
Q47218668 | Hot Spots for Protein Partnerships at the Surface of Cholinesterases and Related α/β Hydrolase Fold Proteins or Domains-A Structural Perspective |
Q55709846 | Identification of new allosteric sites and modulators of AChE through computational and experimental tools. |
Q46025102 | Immunopurification of Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure. |
Q39306292 | Recent developments in structural studies on acetylcholinesterase |
Q48020171 | Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance |
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