review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | David J. Gould | Q73356920 |
P2093 | author name string | Favorov P | |
P2860 | cites work | Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions | Q24531466 |
Site-specific integration by adeno-associated virus | Q24558738 | ||
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters | Q24564850 | ||
Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity | Q24676926 | ||
Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics | Q28141424 | ||
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease | Q28143064 | ||
Transcriptional activation by tetracyclines in mammalian cells | Q28303934 | ||
Plasmid DNA encoding IFN-gamma-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis | Q28574104 | ||
Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette | Q28776104 | ||
A third-generation lentivirus vector with a conditional packaging system | Q29616120 | ||
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo | Q29616612 | ||
Suppression of autoimmune diabetes by viral IL-10 gene transfer | Q30309447 | ||
Targeting human T cells by retroviral vectors displaying antibody domains selected from a phage display library | Q30840200 | ||
Identification of synovium-specific homing peptides by in vivo phage display selection. | Q31107560 | ||
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. | Q33643620 | ||
Progression to the G1b phase of the cell cycle is required for completion of human immunodeficiency virus type 1 reverse transcription in T cells | Q33783211 | ||
Development of multigene and regulated lentivirus vectors | Q33787285 | ||
Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein | Q33794816 | ||
Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector | Q33799667 | ||
Regulated gene expression systems | Q33837136 | ||
Immune responses to adenovirus and adeno-associated virus in humans. | Q33874473 | ||
Modifying the host range properties of retroviral vectors | Q33876131 | ||
Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo | Q33944613 | ||
Brain-specific expression of an exogenous gene after i.v. administration | Q33948080 | ||
Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector | Q33949311 | ||
Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice | Q33950195 | ||
Retroviral vectors | Q34065619 | ||
Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: preliminary clinical results | Q34068061 | ||
Adeno-associated virus vectors for gene therapy: more pros than cons? | Q34080580 | ||
Recent developments in retroviral-mediated gene transduction | Q34084690 | ||
Immunotherapeutic gene transfer into muscle | Q34207629 | ||
CpG motifs in bacterial DNA trigger direct B-cell activation | Q34307394 | ||
Multiple applications for replication-defective herpes simplex virus vectors | Q34366646 | ||
Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set? | Q34382971 | ||
A humanized system for pharmacologic control of gene expression | Q34394730 | ||
Retargeting gene delivery using surface-engineered retroviral vector particles. | Q34403833 | ||
Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors | Q34460148 | ||
Targeted adenoviral vectors | Q34646701 | ||
Endogenous regulation of a therapeutic transgene restores homeostasis in arthritic joints | Q34791340 | ||
The potential for gene therapy in the treatment of autoimmune disease | Q34825228 | ||
Is NF-kappaB a useful therapeutic target in rheumatoid arthritis? | Q34962973 | ||
Antihyperalgesic effects of infection with a preproenkephalin-encoding herpes virus | Q35069305 | ||
High-efficiency gene transfer into skeletal muscle mediated by electric pulses | Q35123357 | ||
C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis | Q35126948 | ||
A regulatory system for use in gene transfer | Q35686843 | ||
Improvement of retroviral retargeting by using amino acid spacers between an additional binding domain and the N terminus of Moloney murine leukemia virus SU. | Q35858034 | ||
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector | Q35872651 | ||
Evaluation of salivary gland acinar and ductal cell-specific promoters in vivo with recombinant adenoviral vectors | Q45882396 | ||
Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells | Q45882436 | ||
A two-component expression system that responds to inflammatory stimuli in vivo | Q45883791 | ||
Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors | Q45884182 | ||
Development of a Langerhans cell-targeted gene therapy format using a dendritic cell-specific promoter. | Q45884233 | ||
Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. | Q45885499 | ||
Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia | Q45886388 | ||
Successful genetic transduction in vivo into synovium by means of electroporation | Q45886837 | ||
Cloning and expression of murine IFN beta and a TNF antagonist for gene therapy of experimental allergic encephalomyelitis | Q45887027 | ||
The efficient expression of intravascularly delivered DNA in rat muscle | Q45887040 | ||
Biodistribution and toxicity studies of VSVG-pseudotyped lentiviral vector after intravenous administration in mice with the observation of in vivo transduction of bone marrow | Q45887432 | ||
Enhanced delivery of naked DNA to the skin by non-invasive in vivo electroporation | Q45888962 | ||
Durable and stratum-specific gene expression in epidermis | Q45889289 | ||
Enhancement of gene expression under hypoxic conditions using fragments of the human vascular endothelial growth factor and the erythropoietin genes | Q45890294 | ||
Local gene therapy with CTLA4-immunoglobulin fusion protein in experimental allergic encephalomyelitis. | Q45890414 | ||
Comparative cytogenetics of hamsters of the genus Calomyscus | Q47891000 | ||
Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo | Q48010592 | ||
In vivo gene delivery to synovium by lentiviral vectors. | Q53974167 | ||
CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice | Q56906450 | ||
Inhibition of experimental autoimmune uveoretinitis by systemic and subconjunctival adenovirus-mediated transfer of the viral IL-10 gene | Q64378400 | ||
Assessment of adenoviral vector safety and toxicity: report of the National Institutes of Health Recombinant DNA Advisory Committee | Q64379319 | ||
Treatment of chronic sialadenitis in a murine model of Sjögren's syndrome by local fasL gene transfer | Q64379911 | ||
Gene Transfer to Synovial Cells by Intra-Articular Administration of Plasmid DNA | Q71787200 | ||
A gene delivery system activatable by disease-associated matrix metalloproteinases | Q73254121 | ||
Protection against autoimmune myocarditis by gene transfer of interleukin-10 by electroporation | Q74459415 | ||
Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood | Q77684631 | ||
Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis | Q77751091 | ||
Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia | Q78019724 | ||
Induction of immunity to antigens expressed by recombinant adeno-associated virus depends on the route of administration | Q40940810 | ||
Efficient transduction of human lymphocytes and CD34+ cells via human immunodeficiency virus-based gene transfer vectors. | Q40957529 | ||
Efficient control of tetracycline-responsive gene expression from an autoregulated bi-directional expression vector | Q40964364 | ||
Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells | Q41008242 | ||
Efficient transgene regulation from a single tetracycline-controlled positive feedback regulatory system | Q41052067 | ||
Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre. | Q41152221 | ||
Versatile retrovirus vector systems for regulated gene expression in vitro and in vivo. | Q41941812 | ||
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain | Q42280576 | ||
Efficient gene transduction by RGD-fiber modified recombinant adenovirus into dendritic cells | Q42501639 | ||
Modulation of erythropoietin delivery from engineered muscles in mice | Q42528988 | ||
Differential expression of tissue-specific promoters by gene gun. | Q42832189 | ||
Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgene-encoded antigen presentation to cytotoxic T cells. | Q43567134 | ||
Lentivirus-mediated gene transfer in primary T cells is enhanced by a central DNA flap. | Q43600028 | ||
Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors | Q43716886 | ||
Dual-regulated expression technology: a new era in the adjustment of heterologous gene expression in mammalian cells | Q43846280 | ||
Therapeutic efficacy in experimental polyarthritis of viral-driven enkephalin overproduction in sensory neurons. | Q43864219 | ||
Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors | Q43867083 | ||
C3-Tat/HIV-regulated intraarticular human interleukin-1 receptor antagonist gene therapy results in efficient inhibition of collagen-induced arthritis superior to cytomegalovirus-regulated expression of the same transgene | Q43907092 | ||
Constitutive and regulated expression of processed insulin following in vivo hepatic gene transfer | Q44042218 | ||
Herpes simplex-mediated gene transfer of nerve growth factor protects against peripheral neuropathy in streptozotocin-induced diabetes in the mouse | Q44043234 | ||
Electroporation-mediated pain-killer gene therapy for mononeuropathic rats | Q44128320 | ||
Five recombinant simian immunodeficiency virus pseudotypes lead to exclusive transduction of retinal pigmented epithelium in rat. | Q44177615 | ||
Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system. | Q44178358 | ||
Human insulin production and amelioration of diabetes in mice by electrotransfer-enhanced plasmid DNA gene transfer to the skeletal muscle | Q44178360 | ||
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences | Q44491759 | ||
Direct gene transfer into mouse muscle in vivo | Q44656494 | ||
Blockade of T cell costimulatory signals using adenovirus vectors prevents both the induction and the progression of experimental autoimmune myocarditis | Q44669497 | ||
Tetracycline-inducible interleukin-10 gene transfer mediated by an adeno-associated virus: application to experimental arthritis | Q45731652 | ||
Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo | Q45731682 | ||
High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter | Q45732758 | ||
Expression of interleukin-4 but not of interleukin-10 from a replicative herpes simplex virus type 1 viral vector precludes experimental allergic encephalomyelitis | Q45736785 | ||
Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritis | Q45739253 | ||
Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist | Q45744151 | ||
Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield | Q45747699 | ||
Gene therapy for rheumatic diseases | Q45855770 | ||
Gene therapy for SCID--a complication after remarkable progress | Q45855795 | ||
Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors | Q45855831 | ||
Astrocyte-specific expression of tyrosine hydroxylase after intracerebral gene transfer induces behavioral recovery in experimental parkinsonism | Q45856399 | ||
Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA). | Q45861247 | ||
Gene therapy death prompts review of adenovirus vector | Q45864618 | ||
Intra-articular IL-4 gene therapy in arthritis: anti-inflammatory effect and enhanced th2activity | Q45864635 | ||
Efficient lipid-mediated gene transfer to articular chondrocytes | Q45865639 | ||
Development of a hypoxia-responsive vector for tumor-specific gene therapy | Q45866583 | ||
Amelioration of established collagen induced arthritis by systemic IL-10 gene delivery | Q45868500 | ||
Soluble complement receptor 1 (CD35) delivered by retrovirally infected syngeneic cells or by naked DNA injection prevents the progression of collagen-induced arthritis | Q45870165 | ||
Regulated hepatic insulin gene therapy of STZ-diabetic rats | Q45872467 | ||
Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue | Q45872828 | ||
A gene therapy approach for treating T-cell-mediated autoimmune diseases | Q45873983 | ||
Central nervous system gene therapy with interleukin-4 inhibits progression of ongoing relapsing-remitting autoimmune encephalomyelitis in Biozzi AB/H mice. | Q45877882 | ||
Expression of hypoxia-inducible factor 1alpha by macrophages in the rheumatoid synovium: implications for targeting of therapeutic genes to the inflamed joint | Q45878755 | ||
Intramuscular plasmid DNA injection can accelerate autoimmune responses. | Q45880047 | ||
Organ distribution of gene expression after intravenous infusion of targeted and untargeted lentiviral vectors. | Q45880348 | ||
Long-term control of erythropoietin secretion by doxycycline in mice transplanted with engineered primary myoblasts | Q45880895 | ||
A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal | Q35915922 | ||
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression | Q36368539 | ||
Vaccination with minigenes encoding V(H)-derived major histocompatibility complex class I-binding epitopes activates cytotoxic T cells that ablate autoantibody-producing B cells and inhibit lupus | Q36371233 | ||
Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells | Q36380346 | ||
Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects | Q36477567 | ||
Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons | Q36557727 | ||
Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector | Q36586077 | ||
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector | Q36663364 | ||
Prevention of diabetes in the NOD mouse by intra-muscular injection of recombinant adeno-associated virus containing the preproinsulin II gene | Q36782146 | ||
NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint | Q36803920 | ||
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector | Q37251114 | ||
Delivery of a stringent dimerizer-regulated gene expression system in a single retroviral vector | Q37288552 | ||
Ecdysone-inducible gene expression in mammalian cells and transgenic mice. | Q37651825 | ||
A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells | Q38313873 | ||
Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure | Q39589248 | ||
Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous system | Q39591444 | ||
Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells | Q39593815 | ||
Interaction of human immunodeficiency virus-derived vectors with wild-type virus in transduced cells. | Q39595638 | ||
Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin | Q39602429 | ||
Development of minimal lentivirus vectors derived from simian immunodeficiency virus (SIVmac251) and their use for gene transfer into human dendritic cells | Q39612180 | ||
Transcriptional targeting of lentiviral vectors by long terminal repeat enhancer replacement | Q39683183 | ||
Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus | Q39685864 | ||
Tetracycline-inducible expression systems with reduced basal activity in mammalian cells | Q39726914 | ||
Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis | Q39946625 | ||
Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis | Q39946646 | ||
Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases | Q40644970 | ||
Fibroblast growth factor-II gene therapy reverts the clinical course and the pathological signs of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice. | Q40690997 | ||
Delivery to the central nervous system of a nonreplicative herpes simplex type 1 vector engineered with the interleukin 4 gene protects rhesus monkeys from hyperacute autoimmune encephalomyelitis | Q40704608 | ||
Development of second- and third-generation bovine immunodeficiency virus-based gene transfer systems | Q40712949 | ||
Enhanced transgene expression in primitive hematopoietic progenitor cells and embryonic stem cells efficiently transduced by optimized retroviral hybrid vectors. | Q40738858 | ||
Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide. | Q40744639 | ||
Lentiviral gene transfer into peripheral blood-derived CD34+ NOD/SCID-repopulating cells | Q40758375 | ||
Cell type specific and glucose responsive expression of interleukin-4 by using insulin promoter and water soluble lipopolymer | Q40788007 | ||
A capsid-modified adenovirus vector devoid of all viral genes: assessment of transduction and toxicity in human hematopoietic cells | Q40790048 | ||
A new-generation stable inducible packaging cell line for lentiviral vectors | Q40801935 | ||
High levels of transgene expression following transduction of long-term NOD/SCID-repopulating human cells with a modified lentiviral vector | Q40804706 | ||
Auto-regulated hepatic insulin gene expression in type 1 diabetic rats. | Q40810183 | ||
Degradable polymeric carrier for the delivery of IL-10 plasmid DNA to prevent autoimmune insulitis of NOD mice | Q40823580 | ||
A novel doxycycline inducible autoregulatory plasmid which displays "on"/"off" regulation suited to gene therapy applications | Q40823590 | ||
Human immunodeficiency virus type 2 lentiviral vectors: packaging signal and splice donor in expression and encapsidation | Q40830211 | ||
Adeno-associated virus production of soluble tumor necrosis factor receptor neutralizes tumor necrosis factor alpha and reduces arthritis | Q40839721 | ||
Lentiviral vectors for enhanced gene expression in human hematopoietic cells | Q40841789 | ||
Streptogramin-based gene regulation systems for mammalian cells | Q40844545 | ||
A stable system for the high-titer production of multiply attenuated lentiviral vectors | Q40860697 | ||
Prolonged transgene expression mediated by a helper-dependent adenoviral vector (hdAd) in the central nervous system | Q40860707 | ||
Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease | Q40892667 | ||
Development of a self-inactivating, minimal lentivirus vector based on simian immunodeficiency virus | Q40896996 | ||
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum | Q40902453 | ||
Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis | Q40923547 | ||
P433 | issue | 10 | |
P921 | main subject | vector-borne disease | Q2083837 |
P304 | page(s) | 912-927 | |
P577 | publication date | 2003-05-01 | |
P1433 | published in | Gene Therapy | Q15763095 |
P1476 | title | Vectors for the treatment of autoimmune disease | |
P478 | volume | 10 |
Q24634560 | Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1 |
Q37801381 | Drug delivery technologies for autoimmune disease |
Q36804669 | Engineering stem cells for therapy |
Q43236657 | Expression Cloning of Recombinant Escherichia coli lacZ Genes Encoding Cytoplasmic and Nuclear β-galactosidase Variants |
Q24812824 | Gene therapy for arthritis--where do we stand? |
Q35906093 | Gene therapy for autoimmune diseases: quo vadis? |
Q41807910 | Gene therapy, early promises, subsequent problems, and recent breakthroughs. |
Q35212648 | Gene therapy: theoretical and bioethical concepts |
Q24793412 | Inhibition of established collagen-induced arthritis with a tumour necrosis factor-alpha inhibitor expressed from a self-contained doxycycline regulated plasmid |
Q38639536 | Long noncoding RNAs and tumorigenesis: genetic associations, molecular mechanisms, and therapeutic strategies |
Q28834149 | Packaging HIV- or FIV-based lentivector expression constructs and transduction of VSV-G pseudotyped viral particles |
Q51641991 | Prevention of experimental autoimmune encephalomyelitis in DA rats by grafting primary skin fibroblasts engineered to express transforming growth factor-beta1. |
Q45859107 | Targeted gene therapy of autoimmune diseases: advances and prospects |
Q40237037 | The effects of N-terminal insertion into VSV-G of an scFv peptide |
Q36448393 | Treatment of human disease by adeno-associated viral gene transfer |
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