Dose selection method for pharmacokinetic study in hemodialysis patients using a subpharmacological dose: oseltamivir as a model drug

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Dose selection method for pharmacokinetic study in hemodialysis patients using a subpharmacological dose: oseltamivir as a model drug is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1047234585
P356DOI10.1186/1471-2369-15-46
P932PMC publication ID3995549
P698PubMed publication ID24636040
P5875ResearchGate publication ID260874057

P2093author name stringJay Wook Lee
Kwon Wook Joo
Chun-Soo Lim
Dong Ki Kim
Jung Pyo Lee
Yon Su Kim
Kook-Hwan Oh
Myounghee Kim
Kyung-Sang Yu
Sejoong Kim
Kwang-Hee Shin
P2860cites workChallenges in developing evidence-based drug dosing guidelines for adults and children receiving renal replacement therapyQ84755388
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Clinical pharmacokinetics of the prodrug oseltamivir and its active metabolite Ro 64-0802.Q33813321
Big physics, small doses: the use of AMS and PET in human microdosing of development drugsQ35075780
Lack of effect of moderate hepatic impairment on the pharmacokinetics of oral oseltamivir and its metabolite oseltamivir carboxylateQ35827008
Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry.Q35884220
Effects of Uremic Toxins on Transport and Metabolism of Different Biopharmaceutics Drug Disposition Classification System XenobioticsQ36634986
Regulatory aspects of pharmacokinetic profiling in special populations: a European perspectiveQ37288795
Pharmacokinetics and dosage adjustment in patients with renal dysfunction.Q37526589
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Nonrenal drug clearance in CKD: Searching for the path less traveledQ37781450
Impact of microdosing clinical study -- why necessary and how useful?Q37800528
What are the important drug use errors in dialysis patients? Pharmacokinetic and pharmacodynamic principlesQ37808682
Predictors of loss of residual renal function among new dialysis patients.Q40775290
The phase 0 microdosing conceptQ41942832
Microdose Study of 14C-Acetaminophen With Accelerator Mass Spectrometry to Examine Pharmacokinetics of Parent Drug and Metabolites in Healthy SubjectsQ42837250
Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS.Q43067629
Drug dosing consideration in patients with acute and chronic kidney disease-a clinical update from Kidney Disease: Improving Global Outcomes (KDIGO).Q44969186
Regulatory Perspectives on Designing Pharmacokinetic Studies and Optimizing Labeling Recommendations for Patients With Chronic Kidney DiseaseQ45815953
Use of microdosing to predict pharmacokinetics at the therapeutic dose: experience with 5 drugsQ48665583
Medication-related problems in ambulatory hemodialysis patients: a pooled analysisQ51925671
Confidence interval criteria for assessment of dose proportionalityQ52069368
The pharmacokinetics and tolerability of the oral neuraminidase inhibitor oseltamivir (Ro 64-0796/GS4104) in healthy adult and elderly volunteersQ53803600
Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen), and phenobarbital in human volunteers.Q54599494
The pharmacokinetics and tolerability of oseltamivir suspension in patients on haemodialysis and continuous ambulatory peritoneal dialysisQ58874874
American College of Clinical Pharmacology position statement on the use of microdosing in the drug development processQ80050350
Hemodialysis acutely improves hepatic CYP3A4 metabolic activityQ80087716
Unexplored pharmacokinetic opportunities with microdosing in oncologyQ80624741
Assessment of the impact of renal impairment on systemic exposure of new molecular entities: evaluation of recent new drug applicationsQ82667897
Pharmacokinetic studies in hemodialysis patientsQ84394949
Nonlinear Pharmacokinetics of Oral Quinidine and Verapamil in Healthy Subjects: A Clinical Microdosing StudyQ84472792
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P921main subjectoseltamivirQ211509
pharmacokineticsQ323936
hemodialysis patientQ126109077
P304page(s)46
P577publication date2014-03-17
P1433published inBMC NephrologyQ15750891
P1476titleDose selection method for pharmacokinetic study in hemodialysis patients using a subpharmacological dose: oseltamivir as a model drug
P478volume15

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