ced-4 and proto-oncogene tfg-1 antagonistically regulate cell size and apoptosis in C. elegans

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ced-4 and proto-oncogene tfg-1 antagonistically regulate cell size and apoptosis in C. elegans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CUB.2008.06.065
P8608Fatcat IDrelease_x2rrn4wmkjeqjm5moif5lsooni
P932PMC publication ID3142714
P698PubMed publication ID18635357
P5875ResearchGate publication ID51409826

P50authorPradeep M JoshiQ57155199
P2093author name stringLing Chen
Joel H Rothman
Tom McCloskey
P2860cites workGlypican LON-2 is a conserved negative regulator of BMP-like signaling in Caenorhabditis elegansQ24293743
The DNA rearrangement that generates the TRK-T3 oncogene involves a novel gene on chromosome 3 whose product has a potential coiled-coil domainQ24311495
Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activityQ24669845
A nucleolar mechanism controlling cell proliferation in stem cells and cancer cellsQ24682602
TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocationsQ28137713
Cloning of the nucleostemin gene and its function in transforming human embryonic bone marrow mesenchymal stem cells into F6 tumor cellsQ28261262
The embryonic cell lineage of the nematode Caenorhabditis elegansQ28271877
Regulation of growth by ploidy in Caenorhabditis elegansQ28301158
Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic developmentQ28595078
Post-embryonic cell lineages of the nematode, Caenorhabditis elegansQ29547748
Characterization of TFG in mus musculus and Caenorhabditis elegansQ30175820
A novel model to identify interaction partners of the PTEN tumor suppressor gene in human bladder cancerQ30442233
Hypoxic preconditioning requires the apoptosis protein CED-4 in C. elegansQ30480836
Analysis of SHP-1-mediated down-regulation of the TRK-T3 oncoprotein identifies Trk-fused gene (TFG) as a novel SHP-1-interacting protein.Q33292197
TGF beta-related pathways. Roles in Caenorhabditis elegans developmentQ33818855
Genetic control of cell sizeQ34026933
The role of ATF/CREB family members in cell growth, survival and apoptosisQ35135752
Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells during early vertebrate developmentQ35221354
Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathwayQ35901845
Developmental apoptosis in C. elegans: a complex CEDnarioQ36403386
Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding proteinQ36475369
Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegansQ37631463
Nonapoptotic role for Apaf-1 in the DNA damage checkpointQ40043968
The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-kappaB pathway.Q40302096
The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemiaQ40433742
Differential effects of X-ALK fusion proteins on proliferation, transformation, and invasion properties of NIH3T3 cellsQ40543147
Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolutionQ42206086
Cooperative regulation of AJM-1 controls junctional integrity in Caenorhabditis elegans epitheliaQ42513083
Role of TFG sequences outside the coiled-coil domain in TRK-T3 oncogenic activation.Q42805238
Role of the TFG N-terminus and coiled-coil domain in the transforming activity of the thyroid TRK-T3 oncogeneQ42832159
GSK3 beta mediates suppression of cyclin D2 expression by tumor suppressor PTEN.Q42834476
Identification of multiple Caenorhabditis elegans caspases and their potential roles in proteolytic cascadesQ43531090
Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy.Q44786855
Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans.Q45973814
Volatile anesthetic preconditioning present in the invertebrate Caenorhabditis elegansQ46739689
The expression of TGFbeta signal transducers in the hypodermis regulates body size in C. elegans.Q47068673
An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitorQ47069461
TFG is a novel fusion partner of NOR1 in extraskeletal myxoid chondrosarcomaQ47367798
Mechanisms for the control of body size by a G-kinase and a downstream TGFbeta signal pathway in Caenorhabditis elegansQ47432014
Apaf-1 Deficiency Causes Chromosomal Instability.Q53511421
Polyploid tissues in the nematode Caenorhabditis elegans.Q55058942
Identification of downstream genes up-regulated by the tumor necrosis factor family member TALL-1Q74542162
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectCaenorhabditis elegansQ91703
Eukaryotic translation initiation factor 2 subunit 2 CELE_K04G2.1Q29794703
Protein tfg-1 CELE_Y63D3A.5Q29797366
Cell death protein 4 CELE_C35D10.9Q29798158
Guanine nucleotide-binding protein-like 3 homolog CELE_K01C8.9Q29804903
CREB-H transcription factor homolog let-607 CELE_F57B10.1Q29805845
P304page(s)1025-1033
P577publication date2008-07-01
P1433published inCurrent BiologyQ1144851
P1476titleced-4 and proto-oncogene tfg-1 antagonistically regulate cell size and apoptosis in C. elegans
P478volume18

Reverse relations

cites work (P2860)
Q37247900Adenine nucleotide translocator cooperates with core cell death machinery to promote apoptosis in Caenorhabditis elegans.
Q34629047C. elegans ADAMTS ADT-2 regulates body size by modulating TGFβ signaling and cuticle collagen organization
Q27303527C. elegans EIF-3.K promotes programmed cell death through CED-3 caspase
Q41610237Developmental control of lateralized neuron size in the nematode Caenorhabditis elegans
Q57139337Dramatic evolution of body length due to postembryonic changes in cell size in a newly discovered close relative of
Q42002512Expression and Localization of TRK-Fused Gene Products in the Rat Brain and Retina
Q34067632Immunohistochemical Localization of an Isoform of TRK-Fused Gene-Like Protein in the Rat Retina.
Q42002493Immunohistochemical Mapping of TRK-Fused Gene Products in the Rat Brainstem.
Q91787702Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death
Q27312169It's all in your mind: determining germ cell fate by neuronal IRE-1 in C. elegans
Q28260191TFG, a target of chromosome translocations in lymphoma and soft tissue tumors, fuses to GPR128 in healthy individuals
Q38761524TFG-Related Neurologic Disorders: New Insights Into Relationships Between Endoplasmic Reticulum and Neurodegeneration
Q38164856The control of cell growth and body size in Caenorhabditis elegans
Q27319353The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans
Q52607336Transgenerational Sterility of Piwi Mutants Represents a Dynamic Form of Adult Reproductive Diapause.
Q42375968Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity

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