| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.TCB.2014.03.002 |
| P8608 | Fatcat ID | release_hzkvkrhefzbd5f45gvl7cz7jua |
| P932 | PMC publication ID | 4342985 |
| P698 | PubMed publication ID | 24721782 |
| P2093 | author name string | Paul H Lerou | |
| Julia C Liu | |||
| Galit Lahav | |||
| P2860 | cites work | p53 has a direct apoptogenic role at the mitochondria | Q24298888 |
| Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis | Q24307994 | ||
| PUMA couples the nuclear and cytoplasmic proapoptotic function of p53 | Q24321694 | ||
| Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation | Q24563808 | ||
| PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome | Q24627524 | ||
| Genome maintenance mechanisms for preventing cancer | Q28131737 | ||
| Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis | Q28144256 | ||
| Etoposide: four decades of development of a topoisomerase II inhibitor | Q28294370 | ||
| Apoptosis: a review of programmed cell death | Q28305845 | ||
| The BCL-2 protein family: opposing activities that mediate cell death | Q29547380 | ||
| Transcriptional control of human p53-regulated genes | Q29617650 | ||
| p53 in health and disease | Q29619939 | ||
| Apoptosis: controlled demolition at the cellular level | Q29620114 | ||
| A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase | Q30488844 | ||
| Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage | Q33469925 | ||
| Energy metabolism in human pluripotent stem cells and their differentiated counterparts | Q33940583 | ||
| High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis. | Q33944653 | ||
| Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim. | Q33990989 | ||
| Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis | Q34076936 | ||
| Survival responses of human embryonic stem cells to DNA damage | Q34078474 | ||
| Human embryonic stem cells express elevated levels of multiple pro-apoptotic BCL-2 family members | Q34103172 | ||
| BH3-Only proteins-essential initiators of apoptotic cell death | Q34117362 | ||
| p53 dynamics control cell fate | Q34173945 | ||
| Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. | Q34312488 | ||
| DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions | Q34328242 | ||
| The role of p53 in determining sensitivity to radiotherapy | Q35058584 | ||
| Dynamics of mitochondrial morphology in healthy cells and during apoptosis | Q35179787 | ||
| CURRENT CONCEPTS OF CANCER | Q35411794 | ||
| Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy | Q35761070 | ||
| The role of DNA damage repair in aging of adult stem cells | Q37045395 | ||
| Molecular regulation of stem cell quiescence. | Q37256787 | ||
| Cytoplasmic functions of the tumour suppressor p53. | Q37466228 | ||
| The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation | Q37517401 | ||
| Transcription-independent p53 apoptosis: an alternative route to death | Q37625305 | ||
| DNA-damage response in tissue-specific and cancer stem cells | Q37826528 | ||
| Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation | Q38128781 | ||
| Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML | Q39260268 | ||
| The tetramerization domain of p53 is required for efficient BAK oligomerization | Q40076203 | ||
| Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase | Q40232134 | ||
| WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization. | Q40323754 | ||
| Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria | Q40763148 | ||
| Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis | Q41822569 | ||
| Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis | Q42225309 | ||
| Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: new insight into the role of mitophagy in cell stemness | Q42257679 | ||
| Sensing radiosensitivity of human epidermal stem cells | Q42513478 | ||
| The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells | Q43143482 | ||
| A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. | Q43211406 | ||
| p53 is required for etoposide-induced apoptosis of human embryonic stem cells | Q46042211 | ||
| Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. | Q46048350 | ||
| Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells | Q47969653 | ||
| A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal. | Q51904571 | ||
| Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia | Q72055352 | ||
| Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts | Q72241934 | ||
| Regulation of apoptosis and differentiation by p53 in human embryonic stem cells | Q79441696 | ||
| MITOCHONDRIA IN TISSUE CULTURE | Q81067591 | ||
| Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells | Q82021764 | ||
| DNA damage response in adult stem cells: pathways and consequences | Q83389981 | ||
| Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death | Q84231670 | ||
| P433 | issue | 5 | |
| P921 | main subject | DNA damage | Q5205747 |
| P304 | page(s) | 268-274 | |
| P577 | publication date | 2014-04-07 | |
| P1433 | published in | Trends in Cell Biology | Q1573994 |
| P1476 | title | Stem cells: balancing resistance and sensitivity to DNA damage | |
| P478 | volume | 24 |
| Q42376493 | A Scaled Framework for CRISPR Editing of Human Pluripotent Stem Cells to Study Psychiatric Disease |
| Q49951210 | A matter of life and death: stem cell survival in tissue regeneration and tumour formation |
| Q37352691 | AKT/GSK3β signaling pathway is critically involved in human pluripotent stem cell survival. |
| Q36226982 | Adrenergic DNA damage of embryonic pluripotent cells via β2 receptor signalling |
| Q28067268 | Apoptosis in Porcine Pluripotent Cells: From ICM to iPSCs |
| Q44917072 | Brief Report: External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas |
| Q39267584 | Canonical microRNAs Enable Differentiation, Protect Against DNA Damage, and Promote Cholesterol Biosynthesis in Neural Stem Cells. |
| Q38864604 | Carbon-ion beams effectively induce growth inhibition and apoptosis in human neural stem cells compared with glioblastoma A172 cells. |
| Q64374729 | Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells |
| Q42704164 | Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts |
| Q35088992 | DNA lesion identity drives choice of damage tolerance pathway in murine cell chromosomes |
| Q26747120 | Evaluating biomarkers to model cancer risk post cosmic ray exposure |
| Q91678555 | Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking |
| Q38871443 | Full biological characterization of human pluripotent stem cells will open the door to translational research |
| Q38691263 | Genome Editing in Human Pluripotent Stem Cells: Approaches, Pitfalls, and Solutions |
| Q42730114 | Genome surveillance in pluripotent stem cells: Low apoptosis threshold and efficient antioxidant defense |
| Q35623892 | High glutathione and glutathione peroxidase-2 levels mediate cell-type-specific DNA damage protection in human induced pluripotent stem cells |
| Q35974864 | Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199 |
| Q41689807 | In trans paired nicking triggers seamless genome editing without double-stranded DNA cutting |
| Q38317505 | Metabolic restructuring and cell fate conversion |
| Q36723084 | Mitochondria in human pluripotent stem cell apoptosis |
| Q99727466 | Modeling the function of BAX and BAK in early human brain development using iPSC-derived systems |
| Q35748670 | Niche signaling promotes stem cell survival in the Drosophila testis via the JAK-STAT target DIAP1 |
| Q34925126 | No DNA damage response and negligible genome-wide transcriptional changes in human embryonic stem cells exposed to terahertz radiation |
| Q36225645 | Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity |
| Q48355615 | Nuclear α-catenin mediates the DNA damage response via β-catenin and nuclear actin |
| Q42371490 | Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells. |
| Q56967903 | Radiation Sensitivity of Adipose-Derived Stem Cells Isolated from Breast Tissue |
| Q41324259 | SIRT1 Enhances the Survival of Human Embryonic Stem Cells by Promoting DNA Repair. |
| Q36771914 | STB-HO, a novel mica fine particle, inhibits the teratoma-forming ability of human embryonic stem cells after in vivo transplantation. |
| Q57191372 | Selective Elimination of Culture-Adapted Human Embryonic Stem Cells with BH3 Mimetics |
| Q47659808 | Stem cells and differentiated cells differ in their sensitivity to urine in vitro |
| Q89482564 | Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds |
| Q39155502 | Technical approaches to induce selective cell death of pluripotent stem cells. |
| Q57276930 | The Impact of Aging on Cancer Progression and Treatment |
| Q37419149 | Unraveling the association between genetic integrity and metabolic activity in pre-implantation stage embryos. |
| Q37550583 | Wildtype adult stem cells, unlike tumor cells, are resistant to cellular damages in Drosophila |
| Q91999654 | X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics |
| Q46315708 | ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors |
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