| scholarly article | Q13442814 |
| P2093 | author name string | Thomas D Hurley | |
| Cynthia A Morgan | |||
| P2860 | cites work | Human aldehyde dehydrogenase. Purification and characterization of a third isozyme with low Km for gamma-aminobutyraldehyde | Q24294278 |
| The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer | Q24323885 | ||
| Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals | Q24598439 | ||
| ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients' outcome | Q24631043 | ||
| Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily | Q24655095 | ||
| Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart | Q24656840 | ||
| Expression and initial characterization of human ALDH3B1 | Q24683659 | ||
| Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
| The structure of retinal dehydrogenase type II at 2.7 A resolution: implications for retinal specificity | Q27618161 | ||
| Human liver mitochondrial aldehyde dehydrogenase: Three-dimensional structure and the restoration of solubility and activity of chimeric forms | Q27620972 | ||
| Structure of daidzin, a naturally occurring anti-alcohol-addiction agent, in complex with human mitochondrial aldehyde dehydrogenase | Q27651091 | ||
| Selective ALDH3A1 inhibition by benzimidazole analogues increase mafosfamide sensitivity in cancer cells. | Q37706367 | ||
| The role of human aldehyde dehydrogenase in normal and cancer stem cells | Q37811959 | ||
| The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance | Q39444027 | ||
| Aldehyde dehydrogenase activity as a functional marker for lung cancer | Q39925109 | ||
| Human liver aldehyde dehydrogenase. Esterase activity | Q39952742 | ||
| N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes | Q40091613 | ||
| Structural and kinetic determinants of aldehyde reduction by aldose reductase | Q40828650 | ||
| Assessment of aldehyde dehydrogenase in viable cells. | Q41345417 | ||
| Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse | Q43823665 | ||
| Multiple conformations of NAD and NADH when bound to human cytosolic and mitochondrial aldehyde dehydrogenase | Q44008734 | ||
| Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype. | Q46170126 | ||
| Substrate specificity of human and yeast aldehyde dehydrogenases | Q46264854 | ||
| Pharmacokinetic and pharmacodynamic basis for partial protection against alcoholism in Asians, heterozygous for the variant ALDH2*2 gene allele | Q46988878 | ||
| Retinal Oxidation Activity and Biological Role of Human Cytosolic Aldehyde Dehydrogenase | Q47571675 | ||
| Increased DNA damage in ALDH2-deficient alcoholics. | Q51719786 | ||
| Horse liver aldehyde dehydrogenase. II. Kinetics and mechanistic implications of the dehydrogenase and esterase activity | Q68640320 | ||
| Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism | Q71010232 | ||
| Metabolism of cyclophosphamide by aldehyde dehydrogenases | Q71549329 | ||
| Cloning and expression of the full-length cDNAS encoding human liver class 1 and class 2 aldehyde dehydrogenase | Q72543272 | ||
| Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant | Q27658903 | ||
| Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases | Q27675184 | ||
| Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases | Q27766377 | ||
| Coot: model-building tools for molecular graphics | Q27860505 | ||
| Optimal description of a protein structure in terms of multiple groups undergoing TLS motion | Q27860825 | ||
| The CCP4 suite: programs for protein crystallography | Q27861090 | ||
| Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1 | Q28117499 | ||
| Mutations in antiquitin in individuals with pyridoxine-dependent seizures | Q28118156 | ||
| Pyridoxal phosphate de-activation by pyrroline-5-carboxylic acid. Increased risk of vitamin B6 deficiency and seizures in hyperprolinemia type II | Q28141266 | ||
| Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes | Q28241500 | ||
| Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application | Q28265682 | ||
| Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems | Q28592801 | ||
| Mutations in the Delta1-pyrroline 5-carboxylate dehydrogenase gene cause type II hyperprolinemia | Q28646386 | ||
| A decade of molecular biology of retinoic acid receptors | Q29619944 | ||
| β-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroids | Q30370274 | ||
| Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics | Q32128781 | ||
| A molecular viewer for the analysis of TLS rigid-body motion in macromolecules | Q33213690 | ||
| Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity. | Q33707099 | ||
| Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines | Q33724209 | ||
| Discovery of novel regulators of aldehyde dehydrogenase isoenzymes | Q33829318 | ||
| Human studies related to protein oxidation: protein carbonyl content as a marker of damage | Q34146688 | ||
| Chemistry and biochemistry of oxidative stress in neurodegenerative disease | Q34263041 | ||
| Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses | Q34301424 | ||
| Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer | Q34420393 | ||
| Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout models | Q35179528 | ||
| Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis. | Q35320772 | ||
| Sjögren-Larsson syndrome. Impaired fatty alcohol oxidation in cultured fibroblasts due to deficient fatty alcohol:nicotinamide adenine dinucleotide oxidoreductase activity | Q35586135 | ||
| Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism. | Q35828024 | ||
| Daidzin: a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase | Q36097296 | ||
| Sjögren-Larsson syndrome: diversity of mutations and polymorphisms in the fatty aldehyde dehydrogenase gene (ALDH3A2). | Q36148787 | ||
| Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health | Q36370381 | ||
| Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase. | Q36767402 | ||
| ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein-protein interactions with HPRT1. | Q37102290 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1964-1975 | |
| P577 | publication date | 2015-02-10 | |
| P1433 | published in | Journal of Medicinal Chemistry | Q900316 |
| P1476 | title | Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors | |
| P478 | volume | 58 |
| Q90724551 | ALDH1A2 Is a Candidate Tumor Suppressor Gene in Ovarian Cancer |
| Q58616388 | Aldehyde Dehydrogenase in Regulatory T Cell Development, Immunity and Cancer |
| Q42107987 | Alternative Biotransformation of Retinal to Retinoic Acid or Retinol by an Aldehyde Dehydrogenase from Bacillus cereus |
| Q58565234 | Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes |
| Q92360116 | Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells |
| Q38443127 | Differentially expressed genes in heads and tails of Angelica sinensis diels: Focusing on ferulic acid metabolism |
| Q37532565 | Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) |
| Q53681299 | Discovery of Orally Bioavailable, Quinoline-based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity. |
| Q58795415 | Family-Four Aldehyde Dehydrogenases Play an Indispensable Role in the Pathogenesis of |
| Q40506281 | Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana). |
| Q46415124 | Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives |
| Q60045468 | Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells |
| Q48117853 | Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors |
| Q27702157 | Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues |
| Q57258271 | Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy |
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