Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface.

scientific article

Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface. is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2014PLoSO...983003R
P356DOI10.1371/JOURNAL.PONE.0083003
P932PMC publication ID3977819
P698PubMed publication ID24709857
P5875ResearchGate publication ID261443682

P50authorWalter AdrianiQ55174861
Angela TinoQ55762345
Adolfo SadileQ58852780
Marcello LeopoldoQ37843300
Claudio ArraQ39050534
Enza LacivitaQ41150790
Giovanni LaviolaQ42057159
Maria NiedduQ42968794
Gianpiero BoattoQ42968808
P2093author name stringLucia A Ruocco
Cristina Pagano
Placido Illiano
Ezio Carboni
Concetta Treno
Ugo A Gironi Carnevale
Fabiana Barbato
P2860cites workLP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptorQ24602670
Neuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapsesQ24619549
Serotonin 5-HT7 receptor agents: Structure-activity relationships and potential therapeutic applications in central nervous system disordersQ24632508
Emerging models of glutamate receptor ion channel structure and functionQ26995713
Searching for a baseline: functional imaging and the resting human brainQ28190070
Functional connectivity in the resting brain: a network analysis of the default mode hypothesisQ29547875
A default mode of brain function: a brief history of an evolving ideaQ29619033
Striatal versus hippocampal representations during win-stay maze performanceQ30486879
Network analyses in neuroimaging studiesQ30640527
Remodeling of neural networks in the anterior forebrain of an animal model of hyperactivity and attention deficits as monitored by molecular imaging probesQ30835729
The Naples High- and Low-Excitability rats: selective breeding, behavioral profile, morphometry, and molecular biology of the mesocortical dopamine system.Q31116246
Recent advances in structural and functional brain imaging studies of attention-deficit/hyperactivity disorderQ31132191
Neurobehavioral adaptations to methylphenidate: the issue of early adolescent exposureQ33837572
Cortico-Basal Ganglia reward network: microcircuitryQ33887052
Estimation of in-vivo neurotransmitter release by brain microdialysis: the issue of validityQ33935785
Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmissionQ33942069
Biochemical correlates of short-term sensitization in Aplysia: temporal analysis of adenylate cyclase stimulation in a perfused-membrane preparationQ34381802
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and diseaseQ34651972
Dopamine phenotype and behaviour in animal models: in relation to attention deficit hyperactivity disorder.Q35587442
Behavioural, pharmacological, morpho-functional molecular studies reveal a hyperfunctioning mesocortical dopamine system in an animal model of attention deficit and hyperactivity disorderQ35587461
Immunization with DAT fragments is associated with long-term striatal impairment, hyperactivity and reduced cognitive flexibility in miceQ36510223
D-Aspartic acid: an endogenous amino acid with an important neuroendocrine roleQ36659679
Temporal asymmetry in activation of Aplysia adenylyl cyclase by calcium and transmitter may explain temporal requirements of conditioningQ37111715
Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonistQ48100455
Regional differences between the immunohistochemical distribution of Ca2+/calmodulin-dependent protein kinase II alpha and beta isoforms in the brainstem of the rat.Q48450695
Does the default-mode functional connectivity of the brain correlate with working-memory performances?Q48486520
Developmental differences in dopamine synthesis inhibition by (+/-)-7-OH-DPAT.Q48647690
Reduced CaMKII-positive neurones in the accumbens shell of an animal model of attention-deficit hyperactivity disorderQ48858135
Evidence for dopamine receptor pruning between adolescence and adulthood in striatum but not nucleus accumbens.Q52204719
Animal models of attention-deficit hyperactivity disorderQ73199073
The 5-HT7 receptor is involved in allocentric spatial memory information processingQ37198117
The glutamate homeostasis hypothesis of addictionQ37538517
Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunctionQ37557593
Attention-deficit/hyperactivity disorder and the dopaminergic hypothesesQ37724221
Overview of glutamatergic neurotransmission in the nervous system.Q37926162
Brain processes in discounting: consequences of adolescent methylphenidate exposureQ37940320
Is dopamine neurotransmission altered in prodromal schizophrenia? A review of the evidenceQ37978959
The glutamatergic neurotransmission in the central nervous system.Q37984378
Integrating neurotransmission in striatal medium spiny neurons.Q37986667
Dopamine neurotransmission and atypical antipsychotics in prefrontal cortex: a critical reviewQ38070834
Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugsQ41326381
What can genetic models tell us about behavioral plasticity?Q41474416
Emotional and risk seeking behavior after prepuberal subchronic or adult acute stimulation of 5-HT7-Rs in Naples High Excitability rats.Q42629945
Sub-chronic exposure to atomoxetine up-regulates BDNF expression and signalling in the brain of adolescent spontaneously hypertensive rats: comparison with methylphenidateQ42943911
Prepuberal subchronic methylphenidate and atomoxetine induce different long-term effects on adult behaviour and forebrain dopamine, norepinephrine and serotonin in Naples high-excitability rats.Q43161642
Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition.Q43787415
Dopamine receptor pruning during the peripubertal period is not attenuated by NMDA receptor antagonism in rat.Q44340832
8-OH-DPAT facilitated memory consolidation and increased hippocampal and cortical cAMP production.Q44698540
The serotonin receptor 7 promotes neurite outgrowth via ERK and Cdk5 signaling pathwaysQ44810223
Excitatory amino acids in the forebrain of the Naples high-excitability rats: neurochemical and behavioural effects of subchronic D-aspartate and its diethyl ester prodrug.Q45753283
Memory time-course: mRNA 5-HT1A and 5-HT7 receptors.Q46008959
Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder with normal controls.Q46037297
Intranasal application of dopamine reduces activity and improves attention in Naples High Excitability rats that feature the mesocortical variant of ADHD.Q46070923
Elevated forebrain excitatory L-glutamate, L-aspartate and D-aspartate in the Naples high-excitability rats.Q46203080
Independent component model of the default-mode brain function: combining individual-level and population-level analyses in resting-state fMRI.Q46287966
D-aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801.Q46325348
5-HT7 receptor stimulation by 8-OH-DPAT counteracts the impairing effect of 5-HT(1A) receptor stimulation on contextual learning in miceQ46369580
Dynamic regulation of glutamatergic postsynaptic activity in rat prefrontal cortex by repeated administration of antipsychotic drugs.Q46771763
An mRNA expression analysis of stimulation and blockade of 5-HT7 receptors during memory consolidationQ46946454
A classical Mendelian cross-breeding study of the Naples high and low excitability rat lines.Q48099355
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectstriatumQ1319792
attentionQ6501338
P304page(s)e83003
P577publication date2014-04-07
P1433published inPLOS OneQ564954
P1476titlePrepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface
P478volume9

Reverse relations

cites work (P2860)
Q486302645-HT7 receptor activation: procognitive and antiamnesic effects
Q36043433An Algorithm to Identify Target-Selective Ligands - A Case Study of 5-HT7/5-HT1A Receptor Selectivity
Q39118764Brain imaging genetics in ADHD and beyond - Mapping pathways from gene to disorder at different levels of complexity.
Q41613761Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study
Q38650429LP-211, a selective 5-HT7 receptor agonist, increases novelty-preference and promotes risk-prone behavior in rats
Q48100455Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonist
Q42057101Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome
Q26800204Serotonin, neural markers, and memory
Q47615306Stimulation of 5-HT7 receptor during adolescence determines its persistent upregulation in adult rat forebrain areas
Q41654337The brain-penetrant 5-HT7 receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain
Q27000420The serotonin receptor 7 and the structural plasticity of brain circuits

Search more.