Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila.

scientific article

Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2003PNAS..100.6404C
P356DOI10.1073/PNAS.1131007100
P932PMC publication ID164459
P698PubMed publication ID12743367
P5875ResearchGate publication ID10763824

P50authorKenneth D. IrvineQ72050167
P2093author name stringJin Jiang
Venizelos Papayannopoulos
Thomas F Vogt
Pamela Woronoff
Trudy Correia
Vladislav Panin
P2860cites workAnnotation of the Drosophila melanogaster euchromatic genome: a systematic reviewQ21092890
A beta-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to beta-1,3-galactosyltransferasesQ22008686
Cloning, expression, and characterization of a novel UDP-galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefromQ22009441
Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase familyQ24290427
Molecular cloning and expression of a human chondroitin synthaseQ24291588
Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the beta 1,3-galactosyltransferase family (beta 3GalT6)Q24291678
Cloning and expression of human core 1 beta1,3-galactosyltransferaseQ24291836
A family of mammalian Fringe genes implicated in boundary determination and the Notch pathwayQ24310459
A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase familyQ24314961
Golgi retention mechanism of beta-1,4-galactosyltransferase. Membrane-spanning domain-dependent homodimerization and association with alpha- and beta-tubulinsQ24317390
Gapped BLAST and PSI-BLAST: a new generation of protein database search programsQ24545170
Crystal structures of the bovine beta 4galactosyltransferase catalytic domain and its complex with uridine diphosphogalactoseQ27618915
Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase IQ27626606
Crystal structure of beta 1,3-glucuronyltransferase I in complex with active donor substrate UDP-GlcUAQ27638844
Crystal structure of beta1,4-galactosyltransferase complex with UDP-Gal reveals an oligosaccharide acceptor binding siteQ27639089
Notch signaling: cell fate control and signal integration in developmentQ27861061
Activity of the yeast MNN1 alpha-1,3-mannosyltransferase requires a motif conserved in many other families of glycosyltransferasesQ27935328
Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in DrosophilaQ28115115
Fringe is a glycosyltransferase that modifies NotchQ28143123
Boundaries in development: formation and functionQ28202940
The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis.Q32162515
Notch signalling pathway and human diseasesQ33540884
Structure/function studies of glycosyltransferasesQ33745420
The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD.Q33909902
Fringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1Q33949989
Modulation of receptor signaling by glycosylation: fringe is an O-fucose-beta1,3-N-acetylglucosaminyltransferaseQ34989571
Identification and characterization of three Drosophila melanogaster glucuronyltransferases responsible for the synthesis of the conserved glycosaminoglycan-protein linkage region of proteoglycans. Two novel homologs exhibit broad specificity towardQ38358997
The Drosophila melanogaster brainiac protein is a glycolipid-specific beta 1,3N-acetylglucosaminyltransferaseQ40716868
Dorsal-ventral signaling in limb developmentQ41678568
GFP-tagged balancer chromosomes for Drosophila melanogasterQ41723368
Protein kinase A and hedgehog signaling in Drosophila limb developmentQ42489490
fringe, a Boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development.Q42694998
Purification, characterization, and subunit structure of rat core 1 Beta1,3-galactosyltransferaseQ43775020
Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.Q45345395
Dorsal-ventral signaling in the Drosophila eye.Q52184255
Secreted fringe-like signaling molecules may be glycosyltransferases.Q52552236
Modulators of Notch signaling.Q52567848
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P304page(s)6404-6409
P577publication date2003-05-12
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMolecular genetic analysis of the glycosyltransferase Fringe in Drosophila
P478volume100

Reverse relations

cites work (P2860)
Q36819707Abnormal vertebral segmentation and the notch signaling pathway in man.
Q33836774Diversity in protein glycosylation among insect species
Q42845643Drosophila glial glutamate transporter Eaat1 is regulated by fringe-mediated notch signaling and is essential for larval locomotion.
Q44844153Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development
Q34241412Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states
Q45162691Functional analysis of Drosophila beta1,4-N-acetlygalactosaminyltransferases
Q34271410Glycosylation regulates Notch signalling.
Q34498292Glycosyltransferase complexes in eukaryotes: long-known, prevalent but still unrecognized
Q90370645Identification of novel LFNG mutations in spondylocostal dysostosis
Q46960525In vitro reconstitution of the modulation of Drosophila Notch-ligand binding by Fringe
Q34572511Many P-element insertions affect wing shape in Drosophila melanogaster
Q36191263MiR-2 family targets awd and fng to regulate wing morphogenesis in Bombyx mori
Q40041521Molecular diagnosis of vertebral segmentation disorders in humans
Q41973440Mummy, A UDP-N-acetylglucosamine pyrophosphorylase, modulates DPP signaling in the embryonic epidermis of Drosophila
Q24540500Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype
Q24323154Mutation of the fucose-specific beta1,3 N-acetylglucosaminyltransferase LFNG results in abnormal formation of the spine
Q34732663Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche
Q35812113Organization of Golgi glycosyltransferases in membranes: complexity via complexes
Q36724360Positional cloning of a Bombyx wingless locus flugellos (fl) reveals a crucial role for fringe that is specific for wing morphogenesis
Q46933085Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats
Q43076807Requirement for a core 1 galactosyltransferase in the Drosophila nervous system.
Q41773509Structural and mechanistic insights into lunatic fringe from a kinetic analysis of enzyme mutants
Q36949362The diversity of O-linked glycans expressed during Drosophila melanogaster development reflects stage- and tissue-specific requirements for cell signaling
Q36342102Xylosylation of the Notch receptor preserves the balance between its activation by trans-Delta and inhibition by cis-ligands in Drosophila

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