Mechanism of pyrethroid pesticide-induced apoptosis: role of calpain and the ER stress pathway

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Mechanism of pyrethroid pesticide-induced apoptosis: role of calpain and the ER stress pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/TOXSCI/KFR111
P932PMC publication ID3155085
P698PubMed publication ID21555338
P5875ResearchGate publication ID51110543

P2093author name stringJason R Richardson
Muhammad M Hossain
P2860cites workAcute pesticide-related illnesses among working youths, 1988-1999.Q23913088
An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12Q24300914
Roles of CHOP/GADD153 in endoplasmic reticulum stressQ24302185
Caspases: the executioners of apoptosisQ24530218
Endoplasmic reticulum stress: cell life and death decisions.Q24536108
Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytesQ24717826
Measurement of protein using bicinchoninic acidQ26778491
Motor neuron disorder simulating ALS induced by chronic inhalation of pyrethroid insecticidesQ28275886
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stressQ28306995
Deltamethrin induces altered expression of P53, Bax and Bcl-2 in rat brainQ28377132
JNK3 mediates paraquat- and rotenone-induced dopaminergic neuron deathQ30498929
Endoplasmic reticulum Ca2+ dysregulation and endoplasmic reticulum stress following in vitro neuronal ischemia: role of Na+-K+-Cl- cotransporterQ33709920
Mitochondrial role in life and death of the cellQ33822627
Mechanism of toxicity in rotenone models of Parkinson's diseaseQ33974271
Role of mitochondria in neuronal apoptosisQ34101361
Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neuronsQ34379655
Mechanisms of pyrethroid insecticide-induced stimulation of calcium influx in neocortical neurons.Q34458630
Management of the cardiovascular complications of tricyclic antidepressant poisoning : role of sodium bicarbonateQ34481279
Mechanisms of pyrethroid neurotoxicity: implications for cumulative risk assessmentQ34506845
Pyrethrin and pyrethroid exposures in the United States: a longitudinal analysis of incidents reported to poison centersQ34723739
Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degenerationQ36188775
Ca2+ signals and death programmes in neuronsQ36328355
Pyrethroid pesticide-induced alterations in dopamine transporter functionQ36584914
Molecular insights into mechanisms of the cell death program: role in the progression of neurodegenerative disordersQ36611767
Calpain-mediated signaling mechanisms in neuronal injury and neurodegenerationQ37237452
Evidence for a separate mechanism of toxicity for the Type I and the Type II pyrethroid insecticidesQ39797376
Etoposide induces protein kinase Cdelta- and caspase-3-dependent apoptosis in neuroblastoma cancer cellsQ39834265
Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's diseaseQ39859599
Influence of lipid-soluble gating modifier toxins on sodium influx in neocortical neuronsQ39964248
Divergent mechanisms of paraquat, MPP+, and rotenone toxicity: oxidation of thioredoxin and caspase-3 activationQ40223933
Sp1 and Sp3 activate transcription of the human dopamine transporter geneQ40437530
Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP+)‐induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degenerationQ40631358
Calpain: new perspectives in molecular diversity and physiological-pathological involvement.Q40694801
Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activationQ40793113
Golden age of insecticide research: past, present, or future?Q40871840
Neuronal ion channels as the target sites of insecticidesQ41139375
Veratridine induces apoptotic death in bovine chromaffin cells through superoxide productionQ41823292
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosisQ42004487
Neurotoxic implications of the agonistic action of CS-syndrome pyrethroids on the N-type Ca(v)2.2 calcium channelQ42650706
Age, dose, and time-dependency of plasma and tissue distribution of deltamethrin in immature ratsQ43138255
Physiologically based pharmacokinetic modeling of deltamethrin: development of a rat and human diffusion-limited model.Q43143778
Influence of dermal exposure to the pyrethroid insecticide deltamethrin on rat brain microanatomy and cholinergic/dopaminergic neurochemistryQ43277609
An alpha-mercaptoacrylic acid derivative (PD150606) inhibits selective motor neuron death via inhibition of kainate-induced Ca2+ influx and not via calpain inhibitionQ43977407
Selective effects of insecticides on nigrostriatal dopaminergic nerve pathways.Q44214162
Deltamethrin induces apoptotic cell death in cultured cerebral cortical neuronsQ44356838
Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degenerationQ44494831
Stress and combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produce neurochemical and neuropathological alterations in cerebral cortex, hippocampus, and cerebellumQ44693709
Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injuryQ45141097
Comparison of urinary concentrations of 3-phenoxybenzoic acid among general residents in rural and suburban areas and employees of pest control firms.Q46002912
The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiationQ46229892
Na+-dependent sources of intra-axonal Ca2+ release in rat optic nerve during in vitro chemical ischemia.Q46776165
Activation of voltage-sensitive sodium channels during oxygen deprivation leads to apoptotic neuronal deathQ47601190
m-Calpain (calcium-activated neutral proteinase) in Alzheimer's disease brainsQ47880216
Deltamethrin induces mitochondrial membrane permeability and altered expression of cytochrome C in rat brainQ48270879
mu-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage.Q50511860
Chronic sequelae and irreversible injuries following acute pyrethroid intoxication.Q51983056
Apoptotic cell death in rat brain following deltamethrin treatment.Q52538038
Deltamethrin induces delayed apoptosis and altered expression of p53 and bax in rat brainQ74107571
Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivityQ79372704
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectpesticideQ131656
apoptotic processQ14599311
P304page(s)512-525
P577publication date2011-05-09
P1433published inToxicological SciencesQ2446966
P1476titleMechanism of pyrethroid pesticide-induced apoptosis: role of calpain and the ER stress pathway
P478volume122

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cites work (P2860)
Q39029637Acute effects of pyrethroids on serotonin release in the striatum of awake rats: an in vivo microdialysis study.
Q36808784Antioxidant properties of Pelargonium graveolens L'Her essential oil on the reproductive damage induced by deltamethrin in mice as compared to alpha-tocopherol.
Q44690727Calpain mediates caspase-dependent apoptosis initiated by hydrogen peroxide in pancreatic acinar AR42J cells
Q44440602Cholinergic dysfunctions and enhanced oxidative stress in the neurobehavioral toxicity of lambda-cyhalothrin in developing rats
Q54956593Computational tool for immunotoxic assessment of pyrethroids toward adaptive immune cell receptors.
Q37418503Coordinated role of voltage-gated sodium channels and the Na+/H+ exchanger in sustaining microglial activation during inflammation.
Q50052150DNA damage and circulating cell free DNA in greenhouse workers exposed to pesticides
Q43920242Deltamethrin induced an apoptogenic signalling pathway in murine thymocytes : exploring the molecular mechanism
Q55311663Deltamethrin resistance in the salmon louse, Lepeophtheirus salmonis (Krøyer): Maternal inheritance and reduced apoptosis.
Q41656509Deltamethrin-induced oxidative stress and mitochondrial caspase-dependent signaling pathways in murine splenocytes
Q35895165Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish
Q39129874Effect of the pesticide, deltamethrin, on Ca2+ signaling and apoptosis in OC2 human oral cancer cells
Q35882991Emodin induces apoptosis of human osteosarcoma cells via mitochondria- and endoplasmic reticulum stress-related pathways
Q36557023Epigenetic Regulation of Dopamine Transporter mRNA Expression in Human Neuroblastoma Cells.
Q28384794Hippocampal ER stress and learning deficits following repeated pyrethroid exposure
Q55424095Inflammatory and cytotoxic effects of bifenthrin in primary microglia and organotypic hippocampal slice cultures.
Q57487049Neurochemical and Behavioral Dysfunctions in Pesticide Exposed Farm Workers: A Clinical Outcome
Q50107838Pesticide Application and Khat Chewing as Predictors of the Neurological Health Outcomes among Pesticide Applicators in a Vector Control Unit, Saudi Arabia.
Q39294216Potential contribution of insecticide exposure and development of obesity and type 2 diabetes
Q36292074Protective Role of Oleuropein against Acute Deltamethrin-Induced Neurotoxicity in Rat Brain
Q39364794Pyrethroid Insecticides Directly Activate Microglia Through Interaction With Voltage-Gated Sodium Channels.
Q91683844Regional Susceptibility to ER Stress and Protection by Salubrinal Following a Single Exposure to Deltamethrin
Q35707037Role of calcium and calpain in the downregulation of voltage-gated sodium channel expression by the pyrethroid pesticide deltamethrin
Q26830320Role of environmental contaminants in the etiology of Alzheimer's disease: a review
Q42727812Signaling pathways involved in 1-octen-3-ol-mediated neurotoxicity in Drosophila melanogaster: implication in Parkinson’s disease
Q38854898Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss
Q89477237Single or combined exposure to chlorpyrifos and cypermethrin provoke oxidative stress and downregulation in monoamine oxidase and acetylcholinesterase gene expression of the rat's brain
Q33660591Structural and electrophysiological dysfunctions due to increased endoplasmic reticulum stress in a long-term pacing model using human induced pluripotent stem cell-derived ventricular cardiomyocytes
Q49137881The Pivotal Role of Ca2+ Homeostasis in PBDE-47-Induced Neuronal Apoptosis
Q39264905The chemical disruption of human metabolism
Q52735764The effects of taurine on permethrininduced cytogenetic and oxidative damage in cultured human lymphocytes.
Q90644438Toxicant-mediated redox control of proteostasis in neurodegeneration
Q52582464Toxoplasma gondii dense granule protein 15 induces apoptosis in choriocarcinoma JEG-3 cells through endoplasmic reticulum stress.
Q38864945Tryptophan fluorescence quenching as a binding assay to monitor protein conformation changes in the membrane of intact mitochondria
Q38696371Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1.
Q28384137Vitamin E attenuates neurotoxicity induced by deltamethrin in rats

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