A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS.

scientific article

A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/17482960802195632
P932PMC publication ID4354803
P698PubMed publication ID18608093

P50authorHiroshi MitsumotoQ90084178
Michael C. GravesQ110725751
Leo McCluskeyQ115277346
P2093author name stringDavid Saperstein
Robert G Miller
Alan Pestronk
Tahseen Mozaffar
Todd Levine
Howard Andrews
Richard J Barohn
Bruce Levin
Richard Bedlack
Kevin Boylan
Eric J Sorenson
Ying-Kuen Cheung
Elizabeth A Kelvin
Julie Rowin
Paul H Gordon
Julaine Florence
Jacqueline Montes
Rup Tandan
Michael Rivner
John Chapin
Robert B Macarthur
Stephen N Scelsa
Jau-Shin Lou
Carolyn Doorish
Kate Bednarz
Combination Drug Selection Trial Study Group
Jerry M Belsh
P2860cites workPhase II/III randomized trial of TCH346 in patients with ALSQ28241484
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutationQ29547561
El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosisQ29619074
Amyotrophic lateral sclerosisQ29619516
Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemiaQ33566349
Efficacy and safety of xaliproden in amyotrophic lateral sclerosis: results of two phase III trialsQ34327603
Mitochondrial involvement in amyotrophic lateral sclerosisQ34535144
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.Q34584573
The role of creatine in the management of amyotrophic lateral sclerosis and other neurodegenerative disordersQ35976264
Selecting promising ALS therapies in clinical trials.Q36666006
Clinical pharmacokinetics of doxycycline and minocyclineQ39571569
A clinical trial of creatine in ALS.Q40469445
Progression rate of ALSFRS-R at time of diagnosis predicts survival time in ALS.Q43441867
Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosisQ43569621
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in miceQ43977943
Minocycline delays disease onset and mortality in a transgenic model of ALS.Q44024931
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosisQ44149270
Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.Q44226809
Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS.Q44296123
A randomized sequential trial of creatine in amyotrophic lateral sclerosisQ44383439
A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosisQ44562245
Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosisQ44726519
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosisQ45291121
Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.Q45299923
A pilot, double-blind, placebo-controlled trial of indinavir in patients with ALS.Q46433161
The ALSFRSr predicts survival time in an ALS clinic populationQ47867763
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS.Q47951637
Performance of the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) in multicenter clinical trialsQ48570656
Outcome measures for early phase clinical trials.Q51906117
The utility of futility.Q53274861
The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III).Q53535985
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.Q55032889
Progression rate of ALSFRS-R at time of diagnosis predicts survival time in ALS.Q55041563
The Timed Up and Go test: Predicting falls in ALSQ58251470
The Amyotrophic Lateral Sclerosis Functional Rating Scale. Assessment of activities of daily living in patients with amyotrophic lateral sclerosis. The ALS CNTF treatment study (ACTS) phase I-II Study GroupQ71098129
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group IIQ71177245
Quality of life in ALS is maintained as physical function declinesQ73550691
Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosisQ74411605
A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)Q77398255
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosisQ77505248
Trial of celecoxib in amyotrophic lateral sclerosisQ79794799
P433issue4
P921main subjectamyotrophic lateral sclerosisQ206901
P304page(s)212-222
P577publication date2008-08-01
P1433published inAmyotrophic Lateral Sclerosis and Other Motor Neuron DisordersQ15759048
P1476titleA novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS.
P478volume9