Melatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease

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Melatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.PBB.2011.06.026
P932PMC publication ID3156390
P698PubMed publication ID21741988
P5875ResearchGate publication ID51479612

P2093author name stringGaurav Patki
Yuen-Sum Lau
P2860cites workParkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synucleinQ26269955
Mitochondrial dysfunction and oxidative damage in parkin-deficient miceQ28593859
Chronic systemic pesticide exposure reproduces features of Parkinson's diseaseQ29614763
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson diseaseQ29619113
Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegenerationQ33401101
Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson's diseaseQ33868426
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's diseaseQ33951094
Age-related structural and functional changes of brain mitochondria.Q34104048
Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.Q34119022
Neuroprotective effect of long-term NDI1 gene expression in a chronic mouse model of Parkinson disorderQ34129621
Human melatonin production decreases with age.Q34190514
Melatonin, mitochondria, and cellular bioenergeticsQ34196319
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseasesQ34679230
Age-environment and gene-environment interactions in the pathogenesis of Parkinson's diseaseQ34711976
Neuroprotective effects and mechanisms of exercise in a chronic mouse model of Parkinson's disease with moderate neurodegenerationQ34812895
Bimodal circadian secretion of melatonin from the pineal gland in a living CBA mouseQ35234949
Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neuronsQ35611727
Mitochondrial dysfunction and age.Q37035864
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Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's diseaseQ40336587
Acute and delayed effects of exercise on human melatonin secretionQ41666358
Mitochondrial complex I deficiency in Parkinson's diseaseQ41821730
Melatonin causes gene expression in aged animals to respond to inflammatory stimuli in a manner differing from that of young animalsQ43215392
Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model.Q43291967
Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatmentQ43759857
Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathwayQ43807426
Circadian rhythms of dopamine and dihydroxyphenyl acetic acid in the mouse striatum: effects of pinealectomy and of melatonin treatmentQ43933401
Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson diseaseQ44013447
Effects of probenecid on striatal dopamine depletion in acute and long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated miceQ44198579
Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's diseaseQ44212285
Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.Q44802800
Melatonin fails to protect against long-term MPTP-induced dopamine depletion in mouse striatumQ44894630
Does melatonin help save dopaminergic cells in MPTP-treated mice?Q46365738
Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned ratsQ46449965
MPTP treatment in mice does not transmit and cause Parkinsonian neurotoxicity in non-treated cagemates through close contactQ46528858
Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's diseaseQ46691979
Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian ratsQ46742263
Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson's diseaseQ46988233
Diurnal rhythm in the central dopamine turnover in the ratQ48174244
The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouseQ48245374
Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat modelQ48248905
A novel mitochondrial 12SrRNA point mutation in parkinsonism, deafness, and neuropathy.Q50493784
A new motor test sensitive to aging and dopaminergic function.Q52235808
Aging and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of dopaminergic neurons in the substantia nigraQ68816621
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectParkinson's diseaseQ11085
P304page(s)704-711
P577publication date2011-07-01
P1433published inPharmacology, Biochemistry and BehaviorQ15716554
P1476titleMelatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease
P478volume99

Reverse relations

cites work (P2860)
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Q35583125Impact of exercise on mitochondrial transcription factor expression and damage in the striatum of a chronic mouse model of Parkinson's disease
Q48160855Melatonin as a mitochondrial protector in neurodegenerative diseases
Q46557476Melatonin attenuates traumatic brain injury-induced inflammation: a possible role for mitophagy
Q48357495Melatonin enhances L-DOPA therapeutic effects, helps to reduce its dose, and protects dopaminergic neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice
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