Renal accumulation of biglycan and lipid retention accelerates diabetic nephropathy.

scientific article

Renal accumulation of biglycan and lipid retention accelerates diabetic nephropathy. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.AJPATH.2011.05.016
P932PMC publication ID3157166
P698PubMed publication ID21723246
P5875ResearchGate publication ID51461578

P50authorLiliana SchaeferQ55296508
P2093author name stringLisa R Tannock
Patricia Wilson
Joel Thompson
Deepa Taneja
Bonnie Mitchell
Katie Brandewie
P2860cites workInteraction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor betaQ24321274
The response-to-retention hypothesis of early atherogenesisQ24629974
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trialQ28214393
Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implicationsQ28253399
Negative regulation of transforming growth factor-beta by the proteoglycan decorinQ28292224
Primary human glomerular endothelial cells produce proteoglycans, and puromycin affects their posttranslational modificationQ28297280
Intraglomerular lipid deposition in routine biopsiesQ68033816
Immunohistological localization of apolipoproteins in the glomeruli in renal disease: specifically apoB and apoEQ68033830
Interactions of low density lipoprotein with rat mesangial cellsQ69704263
Preferential binding of oxidized LDL to rat glomeruli in vivo and cultured mesangial cells in vitroQ70223767
Apolipoproteins and lipoprotein receptors in glomeruli in human kidney diseasesQ70673116
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic miceQ71006993
Proteoglycans and glycosaminoglycans synthesized in vitro by mesangial cells from normal and diabetic ratsQ71114607
The effect of glucose on proteoglycans produced by cultured mesangial cellsQ72106426
Renal hypertrophy is associated with upregulation of TGF-beta 1 gene expression in diabetic BB rat and NOD mouseQ72383093
Platelet-derived growth factor and transforming growth factor-beta 1 differentially affect the synthesis of biglycan and decorin by monkey arterial smooth muscle cellsQ72798923
Expression of transforming growth factor-beta 1 during diabetic renal hypertrophyQ72822585
Expression of decorin, biglycan, and collagen type I in human renal fibrosing diseaseQ73395934
Small proteoglycans in human diabetic nephropathy: discrepancy between glomerular expression and protein accumulation of decorin, biglycan, lumican, and fibromodulinQ73644222
Lipoprotein abnormalities are associated with increased rate of progression of human chronic renal insufficiencyQ73718901
Renal injury in apolipoprotein E-deficient miceQ74606513
Renal expression of fibrotic matrix proteins and of transforming growth factor-beta (TGF-beta) isoforms in TGF-beta transgenic miceQ77361857
Increased decorin mRNA in diabetic mouse kidney and in mesangial and tubular cells cultured in high glucoseQ77551909
Podocyte proteoglycan synthesis is involved in the development of nephrotic syndromeQ28578040
Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol LevelsQ29620696
Elevated levels of beta defensin-1 mRNA in diabetic kidneys of GK rats.Q33193567
Mouse models of diabetic nephropathyQ33821186
Rosuvastatin and cardiovascular events in patients undergoing hemodialysisQ34016806
Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).Q34164324
Mouse models of hyperlipidemia and atherosclerosisQ34169289
Reversibility of renal injury with cholesterol lowering in hyperlipidemic diabetic miceQ34559921
Low density lipoproteins and mitogenic signal transduction processes: role in the pathogenesis of renal diseaseQ34606590
Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injuryQ35103026
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic miceQ35174671
Cellular lipid metabolism and the role of lipids in progressive renal diseaseQ35621071
Decorin deficiency enhances progressive nephropathy in diabetic mice.Q36095577
Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathyQ36133581
SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearanceQ36227219
Proteoglycan mediated lipoprotein retention: a mechanism of diabetic atherosclerosisQ37201521
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptorsQ37433274
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesionsQ37486465
Transforming growth factor-beta regulates production of proteoglycans by mesangial cellsQ38147084
Regulation of biglycan gene expression by transforming growth factor-beta requires MKK6-p38 mitogen-activated protein Kinase signaling downstream of Smad signalingQ38358454
Impact of genetic background on nephropathy in diabetic miceQ39131103
The glomerular mesangiumQ40284542
Biglycan, a Nitric Oxide-regulated Gene, Affects Adhesion, Growth, and Survival of Mesangial CellsQ40651650
Interactions between lipoproteins, glomerular cells and matrix.Q40776214
The extracellular matrix in diabetic nephropathyQ40779247
Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lungQ40806556
Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney diseaseQ41078715
Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-ricQ41664275
Hyperlipidemia and kidney disease: concepts derived from histopathology and cell biology of the glomerulusQ41708679
Proteoglycans synthesized by arterial smooth muscle cells in the presence of transforming growth factor-beta1 exhibit increased binding to LDLsQ43852796
Amelioration of diabetic nephropathy in SPARC-null miceQ44378918
Hyperglycemia and hyperlipidemia act synergistically to induce renal disease in LDL receptor-deficient BALB mice.Q44690546
Hyperlipidemia aggravates renal disease in B6.ROP Os/+ miceQ45085833
Ex vivo transfer of the decorin gene into rat glomerulus via a mesangial cell vector suppressed extracellular matrix accumulation in experimental glomerulonephritisQ45185176
Foam cells generated by a combination of hyperglycemia and hyperlipemia in ratsQ45186670
Can murine diabetic nephropathy be separated from superimposed acute renal failure?Q46545514
Angiotensin II increases vascular proteoglycan content preceding and contributing to atherosclerosis developmentQ46885968
Proteoglycans can mediate renal lipoprotein retentionQ46987479
Main risk factors for nephropathy in type 2 diabetes mellitus are plasma cholesterol levels, mean blood pressure, and hyperglycemia.Q50888604
Regulation of vascular proteoglycan synthesis by metabolic factors associated with diabetes.Q53558779
Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy.Q53579565
Characterization of susceptibility of inbred mouse strains to diabetic nephropathy.Q53846095
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1179-1187
P577publication date2011-06-30
P1433published inThe American Journal of PathologyQ4744259
P1476titleRenal accumulation of biglycan and lipid retention accelerates diabetic nephropathy
P478volume179

Reverse relations

cites work (P2860)
Q38206875Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis
Q39388535Biglycan is a specific marker and an autocrine angiogenic factor of tumour endothelial cells
Q37729228Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants.
Q36481626Biglycan: a multivalent proteoglycan providing structure and signals
Q46621289Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis.
Q34551722Blocking ligand occupancy of the αVβ3 integrin inhibits the development of nephropathy in diabetic pigs
Q36020284Decreased body fat, elevated plasma transforming growth factor-β levels, and impaired BMP4-like signaling in biglycan-deficient mice.
Q26996008Diabetic nephropathy and extracellular matrix
Q35536459Early systemic microvascular damage in pigs with atherogenic diabetes mellitus coincides with renal angiopoietin dysbalance.
Q47693851Elevated circulating TGF-β is not the cause of increased atherosclerosis development in biglycan deficient mice
Q38695983KATP channels in high glucose-induced rat mesangial cell proliferation and release of MMP-2 and fibronectin
Q33819300Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology
Q54646301Liver X receptors preserve renal glomerular integrity under normoglycaemia and in diabetes in mice.
Q47768797Prevention of renal apoB retention is protective against diabetic nephropathy: role of TGF-β inhibition
Q39045202Proposed mechanisms of Terminalia catappa in hyperglycaemia and associated diabetic complications
Q51348247Renoprotective effects of berberine and its possible molecular mechanisms in combination of high-fat diet and low-dose streptozotocin-induced diabetic rats.
Q38184614Role of Toll-like receptors in diabetic nephropathy
Q38120646Role of dyslipidemia in patients with chronic kidney disease
Q47229248Small Leucine-Rich Proteoglycans in Renal Inflammation: Two Sides of the Coin
Q57787207Small leucine rich proteoglycans in host immunity and renal diseases
Q34160971Soluble biglycan as a biomarker of inflammatory renal diseases

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