MicroRNA-520g confers drug resistance by regulating p21 expression in colorectal cancer

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MicroRNA-520g confers drug resistance by regulating p21 expression in colorectal cancer is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M114.620252
P8608Fatcat IDrelease_o2ftc57fn5hkxjguvwgsnwj53e
P932PMC publication ID4358260
P698PubMed publication ID25616665
P5875ResearchGate publication ID271537116

P2093author name stringYang Zhang
Jing Wang
Geoffrey Talmon
Liying Geng
P2860cites workFrequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemiaQ24539231
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemiasQ24564008
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MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)Q24630209
Combinatorial microRNA target predictionsQ27860510
A genetic model for colorectal tumorigenesisQ27860582
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
MicroRNA signatures in human cancersQ27860962
The orphan nuclear receptor SXR coordinately regulates drug metabolism and effluxQ28186424
5-Fluorouracil: mechanisms of action and clinical strategiesQ28201937
Tumor suppressor p53 is a direct transcriptional activator of the human bax geneQ28306186
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MicroRNA-192 suppresses liver metastasis of colon cancerQ33594662
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MicroRNAs in cell proliferation, cell death, and tumorigenesis.Q34497050
5-fluorouracil activation of p53 involves an MDM2-ribosomal protein interactionQ34605000
Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapyQ34752616
Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer.Q34754672
MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells.Q35008686
microPrimer: the biogenesis and function of microRNA.Q36285669
Tamoxifen-stimulated growth of breast cancer due to p21 lossQ36423493
MicroRNAs and chromosomal abnormalities in cancer cellsQ36617820
The p53 miRNA interactome and its potential role in the cancer clinicQ38124951
Restoration of p53/miR-34a regulatory axis decreases survival advantage and ensures Bax-dependent apoptosis of non-small cell lung carcinoma cellsQ39032730
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Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer.Q39660739
p21(Cip1) confers resistance to imatinib in human chronic myeloid leukemia cellsQ39757253
Chemotherapy of Gastrointestinal CancerQ39774854
Induction of p53 and drug resistance following treatment with cisplatin or paclitaxel in ovarian cancer cell linesQ40403231
BCR/ABL recruits p53 tumor suppressor protein to induce drug resistanceQ40502504
Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell linesQ40608301
p21 promotes ceramide-induced apoptosis and antagonizes the antideath effect of Bcl-2 in human hepatocarcinoma cellsQ40914197
Anticancer activity of marine sponge Hyrtios sp. extract in human colorectal carcinoma RKO cells with different p53 status.Q42180939
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sitesQ42419115
p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cellsQ42576880
Genetic polymorphisms of GSTP1 related to response to 5-FU-oxaliplatin-based chemotherapy and clinical outcome in advanced colorectal cancer patientsQ43202920
p53 restoration can overcome cisplatin resistance through inhibition of Akt as well as induction of Bax.Q44511919
Prognostic value of ERCC1, thymidylate synthase, and glutathione S-transferase pi for 5-FU/oxaliplatin chemotherapy in advanced colorectal cancerQ46133125
A p21/WAF1 mutation favors the appearance of drug resistance to paclitaxel in human noncancerous epithelial mammary cellsQ46908395
Transforming growth factor beta induces apoptosis through repressing the phosphoinositide 3-kinase/AKT/survivin pathway in colon cancer cellsQ47735652
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.Q52826936
Ceramide glycosylation potentiates cellular multidrug resistanceQ57373871
Comparison of growth requirements of two human intratumoral colon carcinoma cell lines in monolayer and soft agaroseQ68132129
Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damageQ72910633
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
microRNAQ310899
colorectal carcinomaQ25493920
P1104number of pages11
P304page(s)6215-6225
P577publication date2015-01-23
P1433published inJournal of Biological ChemistryQ867727
P1476titleMicroRNA-520g confers drug resistance by regulating p21 expression in colorectal cancer
P478volume290

Reverse relations

cites work (P2860)
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Q51502591miR-17-5p down-regulation contributes to erlotinib resistance in non-small cell lung cancer cells.
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