Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice.

scientific article

Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1019616033
P356DOI10.1186/S12974-015-0254-3
P932PMC publication ID4359394
P698PubMed publication ID25889790
P5875ResearchGate publication ID273701444

P50authorBradley J TurnerQ56855594
Stephen L. NuttQ42651674
P2093author name stringAngela D'Amico
Nirma D Perera
Rebecca K Sheean
Richard H Weston
P2860cites workAugmentation of T Cell Levels and Responses Induced by Androgen DeprivationQ56888848
Androgens affect muscle, motor neuron, and survival in a mouse model of SOD1-related amyotrophic lateral sclerosisQ57650052
Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosisQ68604243
Lymphocytic infiltration in the spinal cord of patients with amyotrophic lateral sclerosisQ69313856
Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosisQ72208007
Sexual differences in onset of disease and response to exercise in a transgenic model of ALSQ79171295
Effects of castration on thymocyte development in two different models of thymic involutionQ81099199
Reassessing the role of growth hormone and sex steroids in thymic involutionQ81270891
Alternative activation of macrophagesQ27860939
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responsesQ29619908
Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis miceQ33354106
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophyQ34023072
Dihydrotestosterone ameliorates degeneration in muscle, axons and motoneurons and improves motor function in amyotrophic lateral sclerosis model miceQ34273954
Activation of thymic regeneration in mice and humans following androgen blockadeQ34440551
Biochemical and functional characterization of three activated macrophage populations.Q34556828
CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's diseaseQ34596265
Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosisQ34992177
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosisQ35094527
Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissueQ35830662
Macrophage polarization comes of age.Q36287066
Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralizationQ36402763
Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survivalQ36602163
Gonadectomy and dehydroepiandrosterone (DHEA) do not modulate disease progression in the G93A mutant SOD1 rat model of amyotrophic lateral sclerosisQ36816782
CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS.Q36899833
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.Q36968498
Regulatory conversation between antigen presenting cells and regulatory T cells enhance immune suppressionQ37099752
Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsetsQ37137351
Thymic involution, a co-morbidity factor in amyotrophic lateral sclerosisQ37295387
Proteomic studies of nitrated alpha-synuclein microglia regulation by CD4+CD25+ T cellsQ37355257
Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanismsQ37498880
T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?Q37625319
Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthaseQ37714667
Effects of gender in amyotrophic lateral sclerosisQ37825010
Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.Q39712232
Survival motor neuron deficiency enhances progression in an amyotrophic lateral sclerosis mouse model.Q39866409
Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degenerationQ40582001
Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosisQ41215835
Androgen regulates brain-derived neurotrophic factor in spinal motoneurons and their target musculatureQ42214910
Increased androgen receptor expression correlates with development of age-dependent, lobe-specific spontaneous hyperplasia of the brown Norway rat prostateQ43715848
Ovariectomy and 17beta-estradiol modulate disease progression of a mouse model of ALS.Q45029482
Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophyQ47671678
CD4+ T, but not CD8+ or B, lymphocytes mediate facial motoneuron survival after facial nerve transectionQ48213916
C57BL/6J congenic Prp-TDP43A315T mice develop progressive neurodegeneration in the myenteric plexus of the colon without exhibiting key features of ALS.Q48923374
Inflammation in amyotrophic lateral sclerosis spinal cord and brain is mediated by activated macrophages, mast cells and T cellsQ48949631
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)40
P577publication date2015-02-27
P1433published inJournal of NeuroinflammationQ15716679
P1476titleEffect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice
P478volume12