Static retention of the lumenal monotopic membrane protein torsinA in the endoplasmic reticulum

scientific article

Static retention of the lumenal monotopic membrane protein torsinA in the endoplasmic reticulum is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/EMBOJ.2011.233
P932PMC publication ID3160655
P698PubMed publication ID21785409
P5875ResearchGate publication ID51517708

P50authorPhyllis I HansonQ94142273
Teresa V NaismithQ124153599
Abigail B Vander HeydenQ124153618
Erik Lee SnappQ57192502
P2860cites workTargeting proteins to the lumen of endoplasmic reticulum using N-terminal domains of 11beta-hydroxysteroid dehydrogenase and the 50-kDa esteraseQ22009536
Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esteraseQ24293608
TorsinA in PC12 cells: localization in the endoplasmic reticulum and response to stressQ24299130
Biosynthesis of the dystonia-associated AAA+ ATPase torsinA at the endoplasmic reticulumQ24306755
LULL1 retargets TorsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutationQ24311570
TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeletonQ24317502
Membrane lipids: where they are and how they behaveQ24653084
The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER proteinQ24678547
Malectin: A Novel Carbohydrate-binding Protein of the Endoplasmic Reticulum and a Candidate Player in the Early Steps of Protein N-GlycosylationQ27650749
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1Q27731226
The ERD2 gene determines the specificity of the luminal ER protein retention systemQ27938328
A class of membrane proteins shaping the tubular endoplasmic reticulumQ27940194
The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membraneQ28144963
Prostaglandin H synthase-1: evaluation of C-terminus functionQ28307526
Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelopeQ28589351
Dynamics of transitional endoplasmic reticulum sites in vertebrate cellsQ28645796
ER-to-Golgi transport visualized in living cellsQ29547526
Phase separation of integral membrane proteins in Triton X-114 solutionQ29547600
Membrane curvature and mechanisms of dynamic cell membrane remodellingQ29617321
AAA+ proteins: have engine, will workQ29617410
How proteins produce cellular membrane curvatureQ29618016
Sec16A defines the site for vesicle budding from the endoplasmic reticulum on exit from mitosisQ30497404
Structure of UDP-glucuronosyltransferases in membranesQ30805786
Measuring protein mobility by photobleaching GFP chimeras in living cellsQ33316966
MPEx: a tool for exploring membrane proteinsQ33507121
Malectin participates in a backup glycoprotein quality control pathway in the mammalian ER.Q33813564
Helix insertion into bilayers and the evolution of membrane proteinsQ33822760
The length of and nonhydrophobic residues in the transmembrane domain of dengue virus envelope protein are critical for its retention and assembly in the endoplasmic reticulumQ33826597
Torsin A and its torsion dystonia-associated mutant forms are lumenal glycoproteins that exhibit distinct subcellular localizationsQ33907326
A comprehensive comparison of transmembrane domains reveals organelle-specific propertiesQ34083658
TorsinA: movement at many levelsQ34332541
TorsinA in the nuclear envelopeQ34336308
Topogenesis of membrane proteins: determinants and dynamics.Q34353219
Mechanisms determining the morphology of the peripheral ERQ34432619
Morphological analysis of the transfer of VSV ts-045 G glycoprotein from the endoplasmic reticulum to the intermediate compartment in vero cellsQ71591238
C-terminal Ser/Pro-Thr-Glu-Leu tetrapeptides of prostaglandin endoperoxide H synthases-1 and -2 target the enzymes to the endoplasmic reticulumQ71607321
The transmembrane domain of a carboxyl-terminal anchored protein determines localization to the endoplasmic reticulumQ71985086
An internal signal sequence mediates the targeting and retention of the human UDP-glucuronosyltransferase 1A6 to the endoplasmic reticulumQ73107093
Stop-transfer function of pseudo-random amino acid segments during translocation across prokaryotic and eukaryotic membranesQ74267941
The transitional ER defines a boundary for quality control in the secretion of tsO45 VSV glycoproteinQ78383188
Quantitative proteomics analysis of the secretory pathwayQ79438532
The human FK506-binding proteins: characterization of human FKBP19Q83095284
The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding proteinQ34438326
Distinct roles for the AAA ATPases NSF and p97 in the secretory pathwayQ35799558
The organization of endoplasmic reticulum export complexesQ36237498
The torsin-family AAA+ protein OOC-5 contains a critical disulfide adjacent to Sensor-II that couples redox state to nucleotide bindingQ36796834
TorsinA protein degradation and autophagy in DYT1 dystoniaQ37023190
The pathophysiological basis of dystonias.Q37088920
Interaction of torsinA with its major binding partners is impaired by the dystonia-associated DeltaGAG deletionQ37459854
Mechanisms shaping the membranes of cellular organellesQ37540213
Protein folding in membranes.Q37681352
Protein sorting receptors in the early secretory pathwayQ37763713
Molecular pathways in dystoniaQ37816579
The membrane association sequences of the prostaglandin endoperoxide synthases-1 and -2 isozymesQ38331928
Low temperature-induced transport blocks as tools to manipulate membrane traffic.Q38751280
Concept and classification of dystoniaQ39512463
Rer1p, a retrieval receptor for ER membrane proteins, recognizes transmembrane domains in multiple modes.Q39897193
Consequences of the DYT1 mutation on torsinA oligomerization and degradationQ39926996
Transmembrane domain-dependent partitioning of membrane proteins within the endoplasmic reticulumQ39994820
Phosphatidylinositol 4-phosphate formation at ER exit sites regulates ER exportQ40212158
siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cellsQ40260791
Recognition of transmembrane helices by the endoplasmic reticulum translocon.Q40464906
Characterization of human torsinA and its dystonia-associated mutant formQ40643431
Cholesterol and the Golgi apparatusQ40840990
Hepatitis C virus glycoprotein complex localization in the endoplasmic reticulum involves a determinant for retention and not retrieval.Q40993767
Localization of prostaglandin endoperoxide synthase-1 to the endoplasmic reticulum and nuclear envelope is independent of its C-terminal tetrapeptide-PTEL.Q41360565
Temperature and energy dependence of secretory protein transport in the exocrine pancreas.Q41860697
Transmembrane domain-dependent sorting of proteins to the ER and plasma membrane in yeastQ42128889
A novel transmembrane domain mediating retention of a highly motile herpesvirus glycoprotein in the endoplasmic reticulumQ42648710
Generation and characterization of Dyt1 DeltaGAG knock-in mouse as a model for early-onset dystoniaQ42671584
SDS micelles as a membrane-mimetic environment for transmembrane segmentsQ43239665
Bulk flow revisited: transport of a soluble protein in the secretory pathwayQ43496672
Transmembrane domain modulates sorting of membrane proteins in Toxoplasma gondiiQ44824212
Conformational flexibility in crystal structures of human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulationQ45129829
A comparative study of the COX-1 and COX-2 isozymes bound to lipid membranesQ46304025
Molecular code for transmembrane-helix recognition by the Sec61 transloconQ46853934
Determinants of UDP glucuronosyltransferase membrane association and residency in the endoplasmic reticulumQ47774865
Evolutionary biology. Pelvic problems for mammalsQ47778685
Protein folding stability can determine the efficiency of escape from endoplasmic reticulum quality controlQ47792459
Colocalization of fluorescent markers in confocal microscope images of plant cells.Q50639755
Recapture after exocytosis causes differential retention of protein in granules of bovine chromaffin cells.Q50796308
Anchoring of a monotopic membrane protein: the binding of prostaglandin H2 synthase-1 to the surface of a phospholipid bilayer.Q52071525
RGS4 binds to membranes through an amphipathic alpha -helix.Q52538794
Distinct influences of carboxyl terminal segment structure on function in the two isoforms of prostaglandin H synthase.Q52543050
Interaction of monotopic membrane enzymes with a lipid bilayer: a coarse-grained MD simulation study.Q53518474
ATP-Dependent Formation of Phosphatidylserine-Rich Vesicles from the Endoplasmic Reticulum of Leek CellsQ57374030
Tolcapone: COMT inhibition for the treatment of Parkinson's diseaseQ64891739
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
membrane proteinQ423042
P304page(s)3217-3231
P577publication date2011-07-22
P1433published inThe EMBO JournalQ1278554
P1476titleStatic retention of the lumenal monotopic membrane protein torsinA in the endoplasmic reticulum
P478volume30

Reverse relations

cites work (P2860)
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Q86176639Putting a finger in the ring
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Q36849988Site-specific Proteolysis Mobilizes TorsinA from the Membrane of the Endoplasmic Reticulum (ER) in Response to ER Stress and B Cell Stimulation
Q92092210The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn
Q33556224The BiP molecular chaperone plays multiple roles during the biogenesis of torsinA, an AAA+ ATPase associated with the neurological disease early-onset torsion dystonia
Q36934972The genetics of dystonias
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Q36331007The ubiquitin ligase F-box/G-domain protein 1 promotes the degradation of the disease-linked protein torsinA through the ubiquitin-proteasome pathway and macroautophagy.
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Q33887717Two membrane-associated regions within the Nodamura virus RNA-dependent RNA polymerase are critical for both mitochondrial localization and RNA replication

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