| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0024-3205(03)00549-6 |
| P698 | PubMed publication ID | 12899914 |
| P2093 | author name string | Andrew P Smith | |
| Nancy M Lee | |||
| P2860 | cites work | Dynorphin-(1-13): antinociceptive action and its effects on morphine analgesia and acute tolerance | Q67525843 |
| Modulation of mu-mediated antinociception by delta agonists: characterization with antagonists | Q69361510 | ||
| Characterization of dynorphin A-induced antinociception at spinal level | Q69864396 | ||
| Intrathecally administered dynorphin-(1-17) modulates morphine-induced antinociception differently in morphine-naive and morphine-tolerant rats | Q69899455 | ||
| Des-tyrosine-dynorphin antagonizes morphine analgesia | Q70540700 | ||
| Presence of the mu3 opiate receptor in endothelial cells. Coupling to nitric oxide production and vasodilation | Q70808748 | ||
| Dynorphin-(1-13): effects in nontolerant and morphine-dependent rhesus monkeys | Q71840774 | ||
| Dynorphin: a possible modulatory peptide on morphine or beta-endorphin analgesia in mouse | Q72462912 | ||
| Suppression of withdrawal symptoms by dynorphin in heroin addicts | Q72536845 | ||
| Analgesic effects of μ-, δ- and κ-opiate agonists and, in particular, dynorphin at the spinal level | Q72571987 | ||
| Synergistic brainstem interactions for morphine analgesia | Q72636203 | ||
| Microinjection of dynorphin into the supraoptic and paraventricular nuclei produces antidiuretic effects through vasopressin release | Q72670381 | ||
| Interactions of dynorphin A and related peptides with cardiac ouabain binding sites | Q73020238 | ||
| Dynorphin peptides: antagonists of melanocortin receptors | Q73482542 | ||
| Co-activation of Gi and Gq proteins exerts synergistic effect on human platelet aggregation through activation of phospholipase C and Ca2+ signalling pathways | Q77408653 | ||
| G-protein-coupled receptor heterodimerization modulates receptor function | Q24603239 | ||
| Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation | Q28202455 | ||
| Coincident signalling between the Gi/Go-coupled delta-opioid receptor and the Gq-coupled m3 muscarinic receptor at the level of intracellular free calcium in SH-SY5Y cells | Q28205740 | ||
| Cloning of a delta opioid receptor by functional expression | Q28213132 | ||
| Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer | Q28213709 | ||
| Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation | Q28345401 | ||
| Cloning and pharmacological characterization of a rat kappa opioid receptor | Q28378330 | ||
| The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization | Q30800519 | ||
| Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu5 dimerization. | Q31744657 | ||
| A molecular mechanism for signaling between seven-transmembrane receptors: evidence for a redistribution of G proteins | Q33565369 | ||
| Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. | Q33873664 | ||
| Pain modulation: expectation, opioid analgesia and virtual pain. | Q33875378 | ||
| Molecular mechanisms and regulation of opioid receptor signaling | Q33932163 | ||
| Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene | Q33950375 | ||
| G-protein-coupled receptor dimers in the lime light | Q34023321 | ||
| Opioids and their complicated receptor complexes | Q34047403 | ||
| Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal | Q34104454 | ||
| ??? | Q28207849 | ||
| Characteristics of μ and δ opioid binding sites in striatal slices of morphine-tolerant and -dependent mice | Q44334062 | ||
| Mu and delta opioid synergy between the periaqueductal gray and the rostro-ventral medulla | Q44336043 | ||
| Cardiovascular effects of microinjection of dynorphin fragments into the nucleus of the solitary tract (NTS) are mediated by non-opioid mechanisms | Q44338200 | ||
| Simultaneous development of opioid tolerance and opioid antagonist-induced receptor upregulation | Q44338745 | ||
| Promoter region and alternatively spliced exons of the rat mu-opioid receptor gene | Q44341695 | ||
| Effect of kappa-opioid receptor agonists on morphine analgesia in morphine-naive and morphine-tolerant rats | Q44343772 | ||
| Bilateral intranigral microinjection of morphine and opioid peptides produces antinociception in rats | Q44344751 | ||
| The mu-opioid receptor is necessary for [D-Pen2,D-Pen5]enkephalin-induced analgesia | Q44345741 | ||
| Distinct subtypes of the opioid receptor with allosteric interactions in brain membranes | Q44346639 | ||
| Dimerization of the delta opioid receptor: implication for a role in receptor internalization | Q44347088 | ||
| Opioid supraspinal analgesic synergy between the amygdala and periaqueductal gray in rats | Q44347964 | ||
| Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu-receptor. | Q44349908 | ||
| Kappa 3: a novel subtype of the kappa opioid site in bovine adrenal medulla, highly selective for Met-enkephalin-Arg6-Phe7. | Q44351886 | ||
| Comparative distribution of opiate receptors and three opioid peptide neuronal systems in rhesus monkey central nervous system | Q44352362 | ||
| Identification and characterization of three new alternatively spliced mu-opioid receptor isoforms. | Q44352433 | ||
| MAP kinase activation by mu opioid receptor involves phosphatidylinositol 3-kinase but not the cAMP/PKA pathway | Q44352609 | ||
| Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat. | Q44352974 | ||
| High and low affinity opioid binding sites: Relationship to mu and delta sites | Q44353208 | ||
| Interaction of leucine enkephalin with (3H)naloxone binding in rat brain: Evidence for an opioid receptor complex | Q44353485 | ||
| Synergism between the analgesic actions of morphine and pentazocine | Q44573693 | ||
| Antinociceptive effects of [D-Ala2]deltorphin II, a highly selective delta agonist in vivo | Q45139499 | ||
| Effects of dynorphin A(1-13) on opiate withdrawal in humans | Q47794235 | ||
| Loss of antiallodynic and antinociceptive spinal/supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum | Q48158372 | ||
| Identification and molecular characterization of m3 muscarinic receptor dimers | Q48177207 | ||
| Comparison of in vivo and in vitro parameters of opiate receptor binding in naive and tolerant dependent rodents | Q48455184 | ||
| Mechanisms of beta-adrenergic receptor desensitization and resensitization | Q48609403 | ||
| Tolerance to morphine analgesia: decreased multiplicative interaction between spinal and supraspinal sites | Q48634269 | ||
| Multiple mu receptors: evidence for mu2 sites in the guinea pig ileum | Q48760480 | ||
| Kappa binding sites in guinea-pig brain membranes: evidence for a dynorphin-resistant subtype. | Q48854122 | ||
| Modulation of morphine antinociception by peripheral [Leu5]enkephalin: a synergistic interaction. | Q49017560 | ||
| The potentiation of spinal analgesia by leucine enkephalin. | Q51877813 | ||
| Decreased spinal morphine/clonidine antinociceptive synergism in morphine-tolerant mice. | Q54321850 | ||
| U-50,488 blocks the development of morphine tolerance and dependence at a very low dose in guinea pigs | Q59345793 | ||
| Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization | Q34113042 | ||
| Oligomerization of G-protein-coupled transmitter receptors. | Q34205602 | ||
| Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking | Q34389040 | ||
| Heterodimerization of G-protein-coupled receptors in the CNS. | Q34442026 | ||
| Oligomerization of opioid receptors: generation of novel signaling units | Q34489911 | ||
| Opioid tolerance-in search of the holy grail | Q34563130 | ||
| Homo-oligomeric complexes of the yeast alpha-factor pheromone receptor are functional units of endocytosis | Q34748827 | ||
| Endogenous opioid peptides: multiple agonists and receptors | Q34986433 | ||
| Opiate receptor: cooperativity of binding observed in brain slices | Q35054483 | ||
| Crosstalk between Galpha(i)- and Galpha(q)-coupled receptors is mediated by Gbetagamma exchange. | Q35627071 | ||
| Statistical analysis of drug combinations for synergism | Q36155427 | ||
| Morphine-activated opioid receptors elude desensitization by beta-arrestin | Q36280218 | ||
| Homo- and hetero-oligomeric interactions between G-protein-coupled receptors in living cells monitored by two variants of bioluminescence resonance energy transfer (BRET): hetero-oligomers between receptor subtypes form more efficiently than between | Q38289893 | ||
| Pharmacology of dynorphin | Q39468423 | ||
| Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry | Q40093729 | ||
| Distribution and physiological significance of opioid receptors in the brain | Q40134343 | ||
| Opiate (Enkephalin) Receptors of Neuroblastoma Cells: Occurrence in Clusters on the Cell Surface | Q40262943 | ||
| Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization | Q40744546 | ||
| Regulation of delta opioid receptors by delta9-tetrahydrocannabinol in NG108-15 hybrid cells | Q41002898 | ||
| Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells | Q41079818 | ||
| Molecular pharmacology of the opioid receptors. | Q41097336 | ||
| A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. | Q41186190 | ||
| Modulation of mu-mediated antinociception by delta agonists in the mouse: selective potentiation of morphine and normorphine by [D-Pen2,D-Pen5]enkephalin | Q41271778 | ||
| Sensitization to the behavioral effects of cocaine: modulation by dynorphin and kappa-opioid receptor agonists | Q41527783 | ||
| Dopamine D2 receptor dimers and receptor-blocking peptides | Q42063592 | ||
| Recycling and resensitization of delta opioid receptors | Q42832896 | ||
| Role of G-protein beta gamma subunits in the augmentation of P2Y2 (P2U)receptor-stimulated responses by neuropeptide Y Y1 Gi/o-coupled receptors | Q42988493 | ||
| Suppression by dynorphin A-(1-13) of the expression of opiate withdrawal and tolerance in mice | Q43478538 | ||
| Autoradiographic distribution of mu1 and mu2 opioid binding in the mouse central nervous system | Q43607320 | ||
| Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells | Q43611927 | ||
| mu-Opioid receptor downregulation contributes to opioid tolerance in vivo | Q43648934 | ||
| Cross-tolerance studies in the spinal cord of beta-FNA-treated mice provides further evidence for delta opioid receptor subtypes | Q43827852 | ||
| Morphine tolerance in spinal cord is due to interaction between mu- and delta-receptors | Q43830170 | ||
| Mechanism of opioid dependence and interaction between opioid receptors | Q43858843 | ||
| Analgesic synergy and improved motor function produced by combinations of mu-delta- and mu-kappa-opioids | Q43874302 | ||
| mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat. | Q43925271 | ||
| Induction of G protein-coupled receptor kinases 2 and 3 contributes to the cross-talk between mu and ORL1 receptors following prolonged agonist exposure | Q44210689 | ||
| Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice | Q44330314 | ||
| Antinociceptive interactions of opioid delta receptor agonists with morphine in mice: supra- and sub-additivity | Q44330959 | ||
| Up-regulation of [3H]DAMGO and [3H]DTLET opioid binding sites in laminae I-II of the spinal cord in intact and deafferented morphine-tolerant rats | Q44331341 | ||
| Supraspinal mu 2-opioid receptors mediate spinal/supraspinal morphine synergy | Q44331828 | ||
| Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties | Q44331872 | ||
| Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism | Q44332432 | ||
| The opioid peptide dynorphin directly blocks NMDA receptor channels in the rat. | Q44332997 | ||
| CNS levels of mu opioid receptor (MOR-1) mRNA during chronic treatment with morphine or naltrexone | Q44333421 | ||
| Antisense mapping the MOR-1 opioid receptor: evidence for alternative splicing and a novel morphine-6 beta-glucuronide receptor | Q44334055 | ||
| P433 | issue | 15 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1873-1893 | |
| P577 | publication date | 2003-08-01 | |
| P1433 | published in | Life Sciences | Q5256275 |
| P1476 | title | Opioid receptor interactions: local and nonlocal, symmetric and asymmetric, physical and functional | |
| P478 | volume | 73 |
| Q36404602 | 14-Alkoxy- and 14-acyloxypyridomorphinans: μ agonist/δ antagonist opioid analgesics with diminished tolerance and dependence side effects |
| Q36438816 | Delta opioid receptor analgesia: recent contributions from pharmacology and molecular approaches |
| Q37950301 | Epigenetics of µ-opioid receptors: intersection with HIV-1 infection of the central nervous system |
| Q34540970 | Exploring binding properties of agonists interacting with a δ-opioid receptor |
| Q28545281 | Heroin use is associated with suppressed pro-inflammatory cytokine response after LPS exposure in HIV-infected individuals |
| Q36519212 | Modeling and simulation of the human delta opioid receptor |
| Q24557501 | Mu-opioid receptors modulate the stability of dendritic spines |
| Q37349921 | Opiates and the development of post-injury complications: a review. |
| Q64864874 | Opioidergic Modulation of Striatal Circuits, Implications in Parkinson's Disease and Levodopa Induced Dyskinesia |
| Q42269176 | Sensitivity to μ-opioid receptor-mediated anti-nociception is determined by cross-regulation between μ- and δ-opioid receptors at supraspinal level |
| Q44347312 | Stimulation of δ opioid receptor and blockade of nociceptin/orphanin FQ receptor synergistically attenuate parkinsonism. |
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