NADPH oxidase-induced NALP3 inflammasome activation is driven by thioredoxin-interacting protein which contributes to podocyte injury in hyperglycemia

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NADPH oxidase-induced NALP3 inflammasome activation is driven by thioredoxin-interacting protein which contributes to podocyte injury in hyperglycemia is …
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scholarly articleQ13442814

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P356DOI10.1155/2015/504761
P932PMC publication ID4365330
P698PubMed publication ID25834832
P5875ResearchGate publication ID274396785

P2093author name stringChun Zhang
Hui Tang
Hua Su
Pan Gao
Shan Chen
Fang-Fang He
Xian-Fang Meng
Chun-Tao Lei
P2860cites workThe Nalp3 inflammasome is essential for the development of silicosisQ24645580
Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacyQ27488746
Biochemistry and molecular cell biology of diabetic complicationsQ28131781
A role for mitochondria in NLRP3 inflammasome activationQ28131794
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Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting proteinQ28260396
Oxidative stress as a major culprit in kidney disease in diabetesQ28281957
Cryopyrin activates the inflammasome in response to toxins and ATPQ28291313
Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin functionQ28506375
Osthole mitigates progressive IgA nephropathy by inhibiting reactive oxygen species generation and NF-κB/NLRP3 pathwayQ28534656
Thioredoxin-interacting protein links oxidative stress to inflammasome activationQ29614471
Oxidative Stress and Diabetic ComplicationsQ29615423
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvantsQ29615635
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?Q29619524
P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/caspase 1 pathwayQ30409205
Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox geneQ33729668
Redox signaling via lipid raft clustering in homocysteine-induced injury of podocytesQ33733309
High glucose induces podocyte apoptosis by stimulating TRPC6 via elevation of reactive oxygen speciesQ34053587
The NLRP3 inflammasome promotes renal inflammation and contributes to CKD.Q34455462
A possible role of thioredoxin interacting protein in the pathogenesis of streptozotocin-induced diabetic nephropathy.Q53545278
Glomerular cell number in normal subjects and in type 1 diabetic patientsQ57500168
Renal involvement in secondary amyloidosis of Muckle-Wells syndrome: marked improvement of renal function and reduction of proteinuria after therapy with human anti-interleukin-1β monoclonal antibody canakinumabQ58326117
Glomerular cell number in normal subjects and in type 1 diabetic patientsQ73942888
Interleukin-1-receptor antagonist in type 2 diabetes mellitusQ80624568
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Thioredoxin-interacting protein mediates NALP3 inflammasome activation in podocytes during diabetic nephropathyQ87391789
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Vitamin D3 upregulated protein 1 (VDUP1) is a regulator for redox signaling and stress-mediated diseasesQ36623251
NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemiaQ36731427
Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney diseaseQ36788430
Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndromeQ36909900
Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemiaQ37121306
Expression, localization, and function of the thioredoxin system in diabetic nephropathyQ37146420
Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in ratsQ37151470
Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cellsQ37179758
Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failureQ37298478
The NLRP3 inflammasome: a sensor for metabolic danger?Q37675505
Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plantsQ37792599
The thioredoxin system as a therapeutic target in human health and disease.Q38067821
Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasomeQ39299566
Role of CD2-associated protein in albumin overload-induced apoptosis in podocytesQ39618941
Differing caspase-1 activation states in monocyte versus macrophage models of IL-1beta processing and releaseQ40538072
Vitamin D3 up-regulated protein-1 regulates collagen expression in mesangial cellsQ40628313
Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulationQ41888241
Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosisQ45166196
Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway: Diabetes 57:460-469, 2008.Q46568335
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidneyQ46681131
Role of apoptosis signal-regulating kinase 1 in complement-mediated glomerular epithelial cell injuryQ46820717
Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathyQ46870214
A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infectionQ48108353
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjecthyperglycemiaQ271993
inflammasome complexQ412405
P304page(s)504761
P577publication date2015-03-05
P1433published inJournal of Diabetes ResearchQ26841822
P1476titleNADPH oxidase-induced NALP3 inflammasome activation is driven by thioredoxin-interacting protein which contributes to podocyte injury in hyperglycemia
P478volume2015

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cites work (P2860)
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