review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1007/S00345-003-0363-Y |
P698 | PubMed publication ID | 12920560 |
P50 | author | Spencer J. Collis | Q55303040 |
P2093 | author name string | Theodore L DeWeese | |
Kevin Khater | |||
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A hepatocellular carcinoma-specific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin | Q43719922 | ||
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Ionizing radiation potentiates the antitumor efficacy of oncolytic herpes simplex virus G207 by upregulating ribonucleotide reductase. | Q44130120 | ||
Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model | Q44177727 | ||
Manganese superoxide dismutase gene therapy protects against irradiation-induced cystitis | Q44212463 | ||
Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation. | Q44220727 | ||
Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial. | Q44232574 | ||
Ribozyme-mediated inhibition of PKCalpha sensitizes androgen-independent human prostate cancer cells to cisplatin-induced apoptosis | Q44259379 | ||
In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy | Q44269918 | ||
Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors. | Q44387424 | ||
A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA. | Q44845726 | ||
Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer | Q44873808 | ||
A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy | Q45247385 | ||
Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors | Q45299117 | ||
Replication-selective herpes simplex virus type 1 mutant therapy of cervical cancer is enhanced by low-dose radiation | Q45733161 | ||
Preclinical safety evaluation of G207, a replication-competent herpes simplex virus type 1, inoculated intraprostatically in mice and nonhuman primates | Q45737125 | ||
Oncolytic viral therapy for human prostate cancer by conditionally replicating herpes simplex virus 1 vector G207. | Q45739297 | ||
Fractionation and protraction for radiotherapy of prostate carcinoma | Q77227878 | ||
Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer | Q77321070 | ||
Liposome-encapsulated tumor necrosis factor-alpha enhances the effects of radiation against human colon tumor xenografts | Q77362756 | ||
Radiation therapy for clinically localized prostate cancer: a multi-institutional pooled analysis | Q77424028 | ||
Direct evidence that prostate tumors show high sensitivity to fractionation (low alpha/beta ratio), similar to late-responding normal tissue | Q77451468 | ||
Herpes simplex virus | Q77678102 | ||
Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin | Q78358440 | ||
Prostate biopsy status and PSA nadir level as early surrogates for treatment failure: analysis of a prostate cancer randomized radiation dose escalation trial | Q78365368 | ||
A tragic setback | Q78516025 | ||
Lentiviral-mediated RNA interference | Q40675408 | ||
Suicide gene therapy using AAV-HSVtk/ganciclovir in combination with irradiation results in regression of human head and neck cancer xenografts in nude mice | Q40678035 | ||
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex | Q40717443 | ||
Prostate-specific expression of the diphtheria toxin A chain (DT-A): studies of inducibility and specificity of expression of prostate-specific antigen promoter-driven DT-A adenoviral-mediated gene transfer. | Q40735382 | ||
Preclinical study on gene therapy of cervical carcinoma using adeno-associated virus vectors | Q40763368 | ||
Development of synthetic promoters for radiation-mediated gene therapy | Q40770533 | ||
Adenoviral-mediated p53 transgene expression sensitizes both wild-type and null p53 prostate cancer cells in vitro to radiation | Q40836669 | ||
Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase | Q40920540 | ||
Menage à trois: double strand break repair, V(D)J recombination and DNA-PK. | Q40925823 | ||
A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells | Q40935663 | ||
Potential benefit of improved local tumor control in patients with prostate carcinoma | Q40988074 | ||
Identification of diphtheria toxin via screening as a potent cell cycle and p53-independent cytotoxin for human prostate cancer therapeutics | Q41060593 | ||
Sterically stabilized liposomes: a hypothesis on the molecular origin of the extended circulation times | Q41144469 | ||
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. | Q41563742 | ||
The addition of adenovirus type 5 region E3 enables calydon virus 787 to eliminate distant prostate tumor xenografts. | Q41690221 | ||
An antibody-avidin fusion protein specific for the transferrin receptor serves as a delivery vehicle for effective brain targeting: initial applications in anti-HIV antisense drug delivery to the brain. | Q41694333 | ||
The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. | Q41736480 | ||
A good antisense molecule is hard to find | Q41736928 | ||
Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines | Q41814575 | ||
Ionizing radiation does not alter the antitumor activity of herpes simplex virus vector G207 in subcutaneous tumor models of human and murine prostate cancer | Q42353164 | ||
Modulation of innate immunological factors by STEALTH liposome-encapsulated tumor necrosis factor-alpha in a colon tumor xenograft model. | Q42521473 | ||
Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung. | Q42524846 | ||
Oncolytic virotherapy for cancer with the adenovirus dl1520 (Onyx-015): results of phase I and II trials | Q34452020 | ||
Molecular approaches to chemo-radiotherapy. | Q34501927 | ||
Adenoviral gene therapy | Q34537888 | ||
ONYX-015. Onyx Pharmaceuticals | Q34562778 | ||
Tissue-specific expression of an anti-ras ribozyme inhibits proliferation of human malignant melanoma cells | Q34591429 | ||
Targeted adenoviral vectors | Q34646701 | ||
Cancer gene therapy: 'delivery, delivery, delivery' | Q34667233 | ||
Adenoviral vector-mediated gene transfer for human gene therapy | Q34729274 | ||
Gene therapy of prostate cancer: current and future directions | Q34744823 | ||
Pathologic evidence of dose-response and dose-volume relationships for prostate cancer treated with combined external beam radiotherapy and high-dose-rate brachytherapy | Q34786857 | ||
Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy | Q34791438 | ||
Antisense therapy: current status in prostate cancer and other malignancies | Q34980551 | ||
Antisense therapy for cancer--the time of truth | Q34992794 | ||
Replication-defective genomic herpes simplex vectors: design and production | Q35012883 | ||
Liposomal delivery of nucleic acids in vivo | Q35062247 | ||
In vivo DNA electrotransfer | Q35062251 | ||
Adenovirus and adeno-associated virus vectors | Q35062259 | ||
Gene delivery using herpes simplex virus vectors | Q35062264 | ||
Lentiviral vectors for gene delivery into cells | Q35062267 | ||
Progress and prospects: naked DNA gene transfer and therapy | Q35079580 | ||
Therapeutic targets for metastatic prostate cancer | Q35087863 | ||
Modulation of cellular function by TAT mediated transduction of full length proteins | Q35100870 | ||
TAT peptide internalization: seeking the mechanism of entry. | Q35100881 | ||
The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells | Q35858778 | ||
Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0. | Q35871672 | ||
Ribozyme-mediated reversal of the multidrug-resistant phenotype | Q35897342 | ||
Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection | Q36720691 | ||
The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins | Q37162513 | ||
Ribozyme-mediated downregulation of human metallothionein II(a) induces apoptosis in human prostate and ovarian cancer cell lines | Q38292701 | ||
Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells | Q38302961 | ||
Adenovirus-mediated antisense ATM gene transfer sensitizes prostate cancer cells to radiation | Q38307060 | ||
Expression of the coxsackie adenovirus receptor in normal prostate and in primary and metastatic prostate carcinoma: potential relevance to gene therapy. | Q38456204 | ||
Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase. | Q39548922 | ||
Impact of improved local control on survival | Q39731992 | ||
Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer--a preliminary report | Q40595026 | ||
Cancer fears cast doubts on future of gene therapy | Q40603071 | ||
Expression of the DNA-PK binding protein E4-34K fails to confer radiation sensitivity to mammalian cells. | Q40607889 | ||
Oncolytic viral gene therapy for prostate cancer using two attenuated, replication-competent, genetically engineered herpes simplex viruses | Q40632608 | ||
Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207. | Q45747082 | ||
The role of herpes simplex virus glycoproteins in the virus replication cycle. | Q45753486 | ||
Vaccinia virus for human gene therapy. | Q45755568 | ||
A cascade of adenovirus early functions is required for expression of adeno-associated virus | Q45800850 | ||
Regulated expression of diphtheria toxin in prostate cancer cells | Q45855448 | ||
Intraprostatic AD-p53 gene therapy followed by radical prostatectomy: feasibility and preliminary results | Q45857349 | ||
Gene therapy. Seeking the cause of induced leukemias in X-SCID trial | Q45858033 | ||
Cell phenotype specific kinetics of expression of intratracheally injected manganese superoxide dismutase-plasmid/liposomes (MnSOD-PL) during lung radioprotective gene therapy | Q45858427 | ||
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression. | Q45858661 | ||
Gene silencing by adenovirus-delivered siRNA. | Q45859505 | ||
Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1 or B7-2 costimulatory molecules | Q45866282 | ||
T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years. | Q45866838 | ||
Prostate cancer radiosensitization in vivo with adenovirus-mediated p53 gene therapy. | Q45872927 | ||
Overexpression of manganese superoxide dismutase (MnSOD) in whole lung or alveolar type II cells of MnSOD transgenic mice does not provide intrinsic lung irradiation protection | Q45875403 | ||
Prostate-specific targeting using PSA promoter-based lentiviral vectors | Q45880320 | ||
Additional gene therapy with Ad5CMV-p53 enhanced the efficacy of radiotherapy in human prostate cancer cells. | Q45881811 | ||
Radioprotection of lung and esophagus by overexpression of the human manganese superoxide dismutase transgene. | Q45883867 | ||
rAAV-mediated long-term liver-generated expression of an angiogenesis inhibitor can restrict renal tumor growth in mice | Q45886543 | ||
Expression of ribozymes in gene transfer systems to modulate target RNA levels | Q45890110 | ||
BCL2 antisense reduces prostate cancer cell survival following irradiation. | Q46014956 | ||
Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents | Q46061653 | ||
Cationic lipids, phosphatidylethanolamine and the intracellular delivery of polymeric, nucleic acid-based drugs (review). | Q47614304 | ||
Trojan peptides: the penetratin system for intracellular delivery | Q47721580 | ||
Naked DNA and adenoviral immunizations for immunotherapy of prostate cancer: a phase I/II clinical trial. | Q53773145 | ||
System for robotically assisted prostate biopsy and therapy with intraoperative CT guidance. | Q53876538 | ||
Cellular delivery of hammerhead ribozymes conjugated to a transferrin receptor antibody. | Q54095850 | ||
Virus-mediated killing of cells that lack p53 activity | Q59098652 | ||
Improved Survival in Patients with Locally Advanced Prostate Cancer Treated with Radiotherapy and Goserelin | Q59364974 | ||
A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus | Q63343005 | ||
Stepwise dismantling of adenovirus 2 during entry into cells | Q64377608 | ||
Cell-permeable peptides improve cellular uptake and therapeutic gene delivery of replication-deficient viruses in cells and in vivo | Q64377981 | ||
In vivo transfection and/or cross-priming of dendritic cells following DNA and adenoviral immunizations for immunotherapy of cancer--changes in peripheral mononuclear subsets and intracellular IL-4 and IFN-gamma lymphokine profile | Q64379741 | ||
5-Fluorouracil modulation of radiosensitivity in cultured human carcinoma cells | Q68190354 | ||
Definitive irradiation and chemotherapy for radiosensitization in management of anal carcinoma: interim report on Radiation Therapy Oncology Group study no. 8314 | Q69615425 | ||
Age-related changes in the activities of antioxidant enzymes and lipid peroxidation status in ventral and dorsolateral prostate lobes of noble rats | Q71160071 | ||
An uncertain role for p53 gene alterations in human prostate cancers | Q71254302 | ||
Androgen deprivation with radiation therapy compared with radiation therapy alone for locally advanced prostatic carcinoma: a randomized comparative trial of the Radiation Therapy Oncology Group | Q72156114 | ||
Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue | Q72851913 | ||
A phase I trial of autologous CD34+ hematopoietic progenitor cells transduced with an anti-HIV ribozyme | Q73022564 | ||
Pharmacokinetics and tolerability of an antiangiogenic ribozyme (ANGIOZYME) in healthy volunteers | Q73456912 | ||
Expression of antioxidant enzymes in human prostatic adenocarcinoma | Q73676423 | ||
Cell-cycle arrest versus cell death in cancer therapy | Q73677622 | ||
Antisense TRPM-2 oligodeoxynucleotides chemosensitize human androgen-independent PC-3 prostate cancer cells both in vitro and in vivo | Q73803349 | ||
Enhancing efficacy of recombinant anticancer vaccines with prime/boost regimens that use two different vectors | Q73856260 | ||
Risk group dependence of dose-response for biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer | Q74300566 | ||
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice | Q74531314 | ||
Sensitivity of human prostatic carcinoma cell lines to low dose rate radiation exposure | Q74738676 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | adaptive radiation therapy | Q180507 |
prostate cancer | Q181257 | ||
gene therapy | Q213901 | ||
P304 | page(s) | 275-289 | |
P577 | publication date | 2003-08-13 | |
P1433 | published in | World Journal of Urology | Q15750774 |
P1476 | title | Novel therapeutic strategies in prostate cancer management using gene therapy in combination with radiation therapy | |
P478 | volume | 21 |
Q40488102 | Adenovirus-mediated FLT1-targeted proapoptotic gene therapy of human prostate cancer |
Q45880240 | Combined ionizing radiation and sKDR gene delivery for treatment of prostate carcinomas. |
Q36429405 | The present and future for gene and viral therapy of directly accessible prostate and squamous cell cancers of the head and neck |
Q24811943 | U94 alters FN1 and ANGPTL4 gene expression and inhibits tumorigenesis of prostate cancer cell line PC3. |
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