review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S1367-5931(03)00081-4 |
P698 | PubMed publication ID | 12941423 |
P2093 | author name string | Stephen J Lippard | |
Christiana Xin Zhang | |||
P2860 | cites work | Therapeutic radiopharmaceuticals | Q28212219 |
Design and therapeutic application of matrix metalloproteinase inhibitors | Q28212260 | ||
Manganese(III) biliverdin IX dimethyl ester: a powerful catalytic scavenger of superoxide employing the Mn(III)/Mn(IV) redox couple | Q32064368 | ||
Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease | Q33953052 | ||
Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro | Q34047176 | ||
Recognition of cisplatin adducts by cellular proteins | Q34282236 | ||
Cisplatin: from DNA damage to cancer chemotherapy. | Q34348474 | ||
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals | Q34393336 | ||
Transferrin/transferrin receptor-mediated drug delivery. | Q34587503 | ||
Molecular aspects of resistance to antitumor platinum drugs. | Q34866688 | ||
Metal complexing agents as therapies for Alzheimer's disease | Q35019437 | ||
Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin | Q35747835 | ||
A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts | Q36620632 | ||
In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer | Q37352731 | ||
p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells | Q37385633 | ||
Different recognition of DNA modified by aatitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53. | Q38302471 | ||
Antitumor activity of the mixed phosphine gold species chlorotriphenylphosphine-1,3-bis(diphenylphosphino)propanegold(I). | Q40654861 | ||
Testis-specific HMG-domain protein alters the responses of cells to cisplatin | Q40711026 | ||
The anti-metastatic agent imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway | Q40715456 | ||
Hypotensive properties and acute toxicity of trans-[Ru(NH(3))(4)P(OEt)(3)(NO)](PF(6))(3), a new nitric oxide donor | Q40732264 | ||
Mechanistic studies on AMD6221: a ruthenium-based nitric oxide scavenger | Q40743483 | ||
Inhibition of cancer cell growth by ruthenium(II) arene complexes | Q40774119 | ||
High-throughput synthesis and screening of platinum drug candidates | Q40835835 | ||
Gold(III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold(III) compounds | Q40853299 | ||
Antitumor properties of some 2-[(dimethylamino)methyl]phenylgold(III) complexes | Q41144493 | ||
In vivo effects of the controlled NO donor/scavenger ruthenium cyclam complexes on blood pressure | Q42526193 | ||
cis-Dichloroplatinum(II) complexes tethered to 9-aminoacridine-4-carboxamides: synthesis and action in resistant cell lines in vitro. | Q43643253 | ||
Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant. | Q43653393 | ||
Estrogen-derived steroidal metal complexes: agents for cellular delivery of metal centers to estrogen receptor-positive cells. | Q43683418 | ||
Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system | Q43702217 | ||
Design of macromolecular prodrug of cisplatin using dextran with branched galactose units as targeting moieties to hepatoma cells | Q43800374 | ||
Design, synthesis, and biological activity of a novel non-cisplatin-type platinum-acridine pharmacophore | Q43812059 | ||
Mononuclear platinum(II) complex with 2-phenylpyridine ligands showing high cytotoxicity against mouse sarcoma 180 cells acquiring high cisplatin resistance. | Q43821272 | ||
Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells. | Q43922040 | ||
Gold(III) complexes with bipyridyl ligands: solution chemistry, cytotoxicity, and DNA binding properties | Q43946320 | ||
Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A. | Q43968612 | ||
Hematoporphyrin-derived soluble porphyrin-platinum conjugates with combined cytotoxic and phototoxic antitumor activity | Q43977115 | ||
Soluble tetraarylporphyrin-platinum conjugates as cytotoxic and phototoxic antitumor agents | Q43977118 | ||
The interaction of DNA-targeted 9-aminoacridine-4-carboxamide platinum complexes with DNA in intact human cells. | Q43984243 | ||
Topoisomerase II antagonism and anticancer activity of coordinated derivatives of [RuCl(2)(C(6)H(6))(dmso)]. | Q44020716 | ||
DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair | Q44133887 | ||
Cytotoxic acridinylthiourea and its platinum conjugate produce enzyme-mediated DNA strand breaks | Q44148584 | ||
The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiae | Q44187748 | ||
Novel soluble cationic trans-diaminedichloroplatinum(II) complexes that are active against cisplatin resistant ovarian cancer cell lines. | Q44215847 | ||
Electrostatic contribution in the catalysis of O2*- dismutation by superoxide dismutase mimics. MnIIITE-2-PyP5+ versus MnIIIBr8T-2-PyP+. | Q44244866 | ||
Ruthenium(III) polyaminocarboxylate complexes: efficient and effective nitric oxide scavengers | Q44363334 | ||
In vitro and in vivo antitumor properties of tetrakis((trishydroxy- methyl)phosphine)gold(I) chloride. | Q44368091 | ||
Cholic acid-carboplatin compounds (CarboChAPt) as models for specific drug delivery: synthesis of novel carboplatin analogous derivatives and comparison of the cytotoxic properties with corresponding cisplatin compounds | Q44384840 | ||
DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines | Q44446747 | ||
Metal complexes as enzyme inhibitors | Q46308676 | ||
Nucleotide excision repair from site-specifically platinum-modified nucleosomes. | Q51836720 | ||
Structure, Recognition, and Processing of Cisplatin-DNA Adducts. | Q55035583 | ||
Current status of trans-platinum compounds in cancer therapy | Q59172903 | ||
Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464 | Q73752006 | ||
Medicinal inorganic chemistry: introduction | Q77367161 | ||
Metal complexes as photo- and radiosensitizers | Q77367176 | ||
Treatment of Wilson and menkes diseases | Q77367188 | ||
Functional mimics of superoxide dismutase enzymes as therapeutic agents | Q77367198 | ||
P433 | issue | 4 | |
P304 | page(s) | 481-489 | |
P577 | publication date | 2003-08-01 | |
P1433 | published in | Current Opinion in Chemical Biology | Q15758415 |
P1476 | title | New metal complexes as potential therapeutics | |
P478 | volume | 7 |
Q37611695 | 1,10-Phenanthroline-5,6-Dione-Based Compounds Are Effective in Disturbing Crucial Physiological Events of Phialophora verrucosa. |
Q35967907 | A Review of Clinical Translation of Inorganic Nanoparticles. |
Q38956634 | A cancer-targeted nanosystem for delivery of gold(III) complexes: enhanced selectivity and apoptosis-inducing efficacy of a gold(III) porphyrin complex |
Q39524936 | A comparative study of DNA binding and cell cycle phase perturbation by the dinuclear complex of Cd(II) with the condensation product of 2-acetylpyridine and malonic acid dihydrazide N',N'(2) -bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide |
Q58921543 | A dinuclear cyclometalated gold(iii)–phosphine complex targeting thioredoxin reductase inhibits hepatocellular carcinoma in vivo |
Q34169479 | A novel copper complex induces paraptosis in colon cancer cells via the activation of ER stress signalling |
Q39181502 | A platinum complex that binds non-covalently to DNA and induces cell death via a different mechanism than cisplatin |
Q35868560 | A review of selected anti-tumour therapeutic agents and reasons for multidrug resistance occurrence |
Q39261012 | A tri-copper(II) complex displaying DNA-cleaving properties and antiproliferative activity against cancer cells |
Q40673716 | Activity of fluconazole and its Cu(II) complex towards Candida species. |
Q41680103 | Acute and subchronic toxicity of the antitumor agent rhodium (II) citrate in Balb/c mice after intraperitoneal administration. |
Q40737623 | Albumin binding and ligand-exchange processes of the Ru(III) anticancer agent NAMI-A and its bis-DMSO analogue determined by ENDOR spectroscopy |
Q30855124 | An unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency |
Q59101621 | Anticancer Activities of Mononuclear Ruthenium(II) Coordination Complexes |
Q59082814 | Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes |
Q39541261 | Anticancer gold(I)-phosphine complexes as potent autophagy-inducing agents |
Q36687247 | Antitumor effect and toxicity of free rhodium (II) citrate and rhodium (II) citrate-loaded maghemite nanoparticles in mice bearing breast cancer |
Q87732541 | Apoptotic effects of dipyrido [3,2-a:2',3'-c] phenazine (dppz) Au(III) complex against diethylnitrosamine/phenobarbital induced experimental hepatocarcinogenesis in rats |
Q36560196 | Axial ligand exchange of N-heterocyclic cobalt(III) Schiff base complexes: molecular structure and NMR solution dynamics. |
Q34509157 | BODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics. |
Q45858014 | Binding of Cu(II) complexes of oxicam NSAIDs to alternating AT and homopolymeric AT sequences: differential response to variation in backbone structure |
Q58172250 | Biological activity of synthetic ionophores: ion transporters as prospective drugs? |
Q39801632 | Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells. |
Q33199658 | Biophysical characterization and molecular modeling of the coordinative-intercalative DNA monoadduct of a platinum-acridinylthiourea agent in a site-specifically modified dodecamer |
Q57528873 | Bis(o-methylserotonin)-containing iridium(III) and ruthenium(II) complexes as new cellular imaging dyes: synthesis, applications, and photophysical and computational studies |
Q38623221 | Bovine Serum Albumin Interactions with Metal Complexes |
Q36823229 | Catalytic organometallic anticancer complexes |
Q38986073 | Catecholase activity, DNA cleavage and cytotoxicity of six Zn(II) complexes synthesized from designed Mannich ligands: higher reactivity of mononuclear over dinuclear. |
Q39991099 | Cellular uptake and distribution of cobalt complexes of fluorescent ligands |
Q50288394 | Characterization of the Activities of Dinuclear Thiolato-Bridged Arene Ruthenium Complexes against Toxoplasma gondii |
Q52553038 | Cisplatin and cisplatin analogues perfusion through isolated rat heart: the effects of acute application on oxidative stress biomarkers. |
Q37855898 | Copper, gold and silver compounds as potential new anti-tumor metallodrugs |
Q51001771 | Covalent binding and conformational change of pUC19 DNA by rhodium (II) metal complex. |
Q46881282 | Cucurbit[n]uril binding of platinum anticancer complexes |
Q57371914 | Cyclotriphosphazene-Pt-DACH Conjugates with Dipeptide Spacers for Drug Delivery Systems |
Q59793490 | Cytotoxic phenanthroline derivatives alter metallostasis and redox homeostasis in neuroblastoma cells |
Q27702884 | Cytotoxic properties of a new organometallic platinum(II) complex and its gold(I) heterobimetallic derivatives |
Q39402733 | Cytotoxicity and DNA interactions of some platinum(II) complexes with substituted benzimidazole ligands. |
Q39689905 | Cytotoxicity in human cancer cells and mitochondrial dysfunction induced by a series of new copper(I) complexes containing tris(2-cyanoethyl)phosphines. |
Q45811861 | DNA binding and oxidative DNA cleavage activity of (mu-oxo)diiron(iii) complexes in visible light. |
Q31043552 | DNA binding properties, histidine interaction and cytotoxicity studies of water soluble ruthenium(ii) terpyridine complexes. |
Q57289654 | DNA binding, cleavage and cytotoxicity studies of three mononuclear Cu(II) chloro-complexes containing N-S donor Schiff base ligands |
Q39668149 | DNA binding, cytotoxicity, and apoptotic-inducing activity of ruthenium(II) polypyridyl complex. |
Q33835903 | DNA binding, prominent DNA cleavage and efficient anticancer activities of tris(diimine)iron(II) complexes |
Q34042848 | DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences |
Q92465999 | Design, Synthesis, and Targeted Delivery of Fluorescent 1,2,4-Triazole-Peptide Conjugates to Pediatric Brain Tumor Cells |
Q38974558 | Designing metallodrugs with nuclease and protease activity. |
Q37687110 | Developing an anticancer copper(II) pro-drug based on the nature of cancer cell and human serum albumin carrier IIA subdomain: mouse model of breast cancer |
Q39695089 | Discrepancy between in vitro and in vivo antitumor effect of a new platinum(II) metallointercalator |
Q57615028 | Dispersed Gold Nanoparticles Supported in the Pores of Siliceous Mesocellular Foam: A Catalyst for Cycloisomerization of Alkynoic Acids to γ-Alkylidene Lactones |
Q38221279 | Enhancing vascular relaxing effects of nitric oxide-donor ruthenium complexes |
Q53223436 | Evaluation of reproductive toxicity in male rats treated with novel synthesized ruthenium(II) and gold(I)-NHC complexes. |
Q39746460 | Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study |
Q40663635 | Exploring the copper(II)-aminotriazole complex-binding sites of human serum albumin |
Q34778423 | Free Rhodium (II) citrate and rhodium (II) citrate magnetic carriers as potential strategies for breast cancer therapy |
Q52860466 | Genotoxicity of Casiopeina III-Ea in mouse bone marrow cells. |
Q39166884 | Gold amides as anticancer drugs: synthesis and activity studies |
Q33279394 | Gold(I)-isocyanide and gold(I)-carbene complexes as substrates for the laser decoration of gold onto ceramic surfaces |
Q86191005 | Gold-phosphine-porphyrin as potential metal-based theranostics |
Q55652601 | High-Technology Therapy Using Biomolecules or Synthetic Compounds for HIV Inhibition |
Q38827449 | Highly Stable Tetra-Phenolato Titanium(IV) Agent Formulated into Nanoparticles Demonstrates Anti-Tumoral Activity and Selectivity |
Q38968421 | Highly cytotoxic DNA-interacting copper(II) coordination compounds |
Q38796884 | In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(iv) complex |
Q36662593 | In vitro evaluation of a stable monomeric gold(II) complex with hematoporphyrin IX: cytotoxicity against tumor and kidney cells, cellular accumulation, and induction of apoptosis. |
Q39728594 | In vitro pharmacological study of monomeric platinum(III) hematoporphyrin IX complexes. |
Q60212615 | Influence of the Diketonato Ligand on the Cytotoxicities of [Ru(η6-p-cymene)(R2acac)(PTA)]+ Complexes (PTA = 1,3,5-triaza-7-phosphaadamantane) |
Q39028760 | Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies |
Q27687736 | Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(III) compound |
Q27695726 | Interactions of gold-based drugs with proteins: the structure and stability of the adduct formed in the reaction between lysozyme and the cytotoxic gold(III) compound Auoxo3 |
Q50452519 | Interfacial properties and in vitro cytotoxic effects of surface-modified near infrared absorbing Au-Au(2)S nanoparticles |
Q48218977 | Iridium Complexes as a Roadblock for DNA Polymerase during Amplification |
Q58383629 | Iridium(III) Complexes of Terpyridine- and Terpyridine-Analogous Ligands Bearing Sugar Residues and Their in vitro Activity |
Q36539791 | Light-Sensitive Ruthenium Complex-Loaded Cross-linked Polymeric Nanoassemblies for the Treatment of Cancer |
Q37824297 | Mass spectrometry as test bench for medicinal chemistry studies |
Q37354918 | Mechanism of cellular uptake of a ruthenium polypyridyl complex |
Q37996311 | Mercury-based traditional herbo-metallic preparations: a toxicological perspective. |
Q64083772 | Metal-Ligand Recognition Index Determination by NMR Proton Relaxation Study |
Q37382191 | Metals in anticancer therapy: copper(II) complexes as inhibitors of the 20S proteasome |
Q42560798 | Methods to explore cellular uptake of ruthenium complexes |
Q35625019 | Mixed ligand copper(II) dicarboxylate complexes: the role of co-ligand hydrophobicity in DNA binding, double-strand DNA cleavage, protein binding and cytotoxicity |
Q36514784 | Modeling anticancer drug-DNA interactions via mixed QM/MM molecular dynamics simulations |
Q37767597 | Molecular modeling and dynamics studies with explicit inclusion of electronic polarizability. Theory and applications |
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Q37703236 | Neutron activation increases activity of ruthenium-based complexes and induces cell death in glioma cells independent of p53 tumor suppressor gene. |
Q38777400 | New Look on 3-Hydroxyiminoflavanone and Its Palladium(II) Complex: Crystallographic and Spectroscopic Studies, Theoretical Calculations and Cytotoxic Activity. |
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Q39153295 | Novel tetranuclear triarylantimony(V) complexes with (±)-mandelic acid ligands: synthesis, characterization, in vitro cytotoxicity and DNA binding properties |
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Q37277525 | Photoinduced electron transfer from PbS quantum dots to cobalt(III) Schiff base complexes: light activation of a protein inhibitor |
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Q39327176 | Potential cytotoxic and amoebicide activity of first row transition metal compounds with 2,9-bis-(2',5'-diazahexanyl)-1,1-phenanthroline (L1). |
Q38551590 | Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) liriodenine with metal ions, and DNA binding studies. |
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Q47970194 | Ru(II)/diphenylphosphine/pyridine-6-thiolate complexes induce S-180 cell apoptosis through intrinsic mitochondrial pathway involving inhibition of Bcl-2 and p53/Bax activation. |
Q41924405 | Ruthenation of Non-stacked Guanines in DNA G-Quadruplex Structures: Enhancement of c-MYC Expression. |
Q39280971 | Ruthenium complexes containing 2,6-bis(benzimidazolyl)pyridine derivatives induce cancer cell apoptosis by triggering DNA damage-mediated p53 phosphorylation |
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Q37982323 | Ruthenium(II) polypyridyl complexes and DNA--from structural probes to cellular imaging and therapeutics. |
Q39121561 | Ruthenium-Arene-β-Carboline Complexes as Potent Inhibitors of Cyclin-Dependent Kinase 1: Synthesis, Characterization and Anticancer Mechanism Studies. |
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Q37226453 | Upregulated expression of FGF13/FHF2 mediates resistance to platinum drugs in cervical cancer cells |
Q39184979 | Zinc(II) complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers that trigger DNA damage-mediated p53 phosphorylation in cancer cells. |
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