Bleomycin-induced pulmonary fibrosis in hamsters. An alveolar macrophage product increases fibroblast prostaglandin E2 and cyclic adenosine monophosphate and suppresses fibroblast proliferation and collagen production

scientific article published on December 1, 1983

Bleomycin-induced pulmonary fibrosis in hamsters. An alveolar macrophage product increases fibroblast prostaglandin E2 and cyclic adenosine monophosphate and suppresses fibroblast proliferation and collagen production is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI111173
P953full work available at URLhttps://europepmc.org/articles/PMC437049
http://www.jci.org/articles/view/111173/files/pdf
https://europepmc.org/articles/PMC437049?pdf=render
P932PMC publication ID437049
P698PubMed publication ID6196378
P5875ResearchGate publication ID17000625

P2093author name stringJ. G. Clark
B. A. Marino
K. M. Kostal
P2860cites workA macrophage-dependent factor that stimulates the proliferation of fibroblasts in vitroQ42588830
Control of collagen production by human diploid lung fibroblasts.Q42802109
Elastase release from human alveolar macrophages: comparison between smokers and nonsmokersQ44908234
Regulation of protein synthesis in chick oviduct. 3. Mechanism of ovalbumin "superinduction" by actinomycin D.Q48006767
Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteinsQ68622613
Bronchoalveolar fibronectin in smokers and nonsmokersQ70993894
Alveolar macrophage suppression of canine bronchoalveolar lymphocytes: the role of prostaglandin E2 in the inhibition of mitogen-responsesQ71144088
Bleomycin-induced synthesis of type I procollagen by human lung and skin fibroblasts in cultureQ72615070
Collagen biosynthesis in bleomycin-induced pulmonary fibrosis in hamstersQ72620824
Modulation of collagen production following bleomycin-induced pulmonary fibrosis in hamsters. Presence of a factor in lung that increases fibroblast prostaglandin E2 and cAMP and suppresses fibroblast proliferation and collagen productionQ72667976
A photometric method for the determination of prolineQ73755144
Protein measurement with the Folin phenol reagentQ20900776
A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acidQ26778512
Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1).Q35351525
Inhibition of collagen synthesis by mononuclear cell supernatesQ36343113
Synthesis of leukotriene C and other arachidonic acid metabolites by mouse pulmonary macrophagesQ36346200
Alterations in collagen production in mixed mononuclear leukocyte-fibroblast culturesQ36347298
Secretion of a specific collagenase by stimulated macrophagesQ36358286
Human alveolar macrophage growth factor for fibroblasts. Regulation and partial characterizationQ36986920
Fibronectin in human bronchopulmonary lavage fluid. Elevation in patients with interstitial lung diseaseQ37014026
Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin productionQ37020888
Prostaglandins and thromboxanesQ37802829
Isoelectric focusing of macrophage culture media and the effect of the fractions on the synthesis of DNA and collagen by fibroblastsQ39290801
Increased elastin and collagen content in the lungs of hamsters receiving an intratracheal injection of bleomycinQ39482874
Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin: pathology and stereologyQ39495941
Association in normal human fibroblasts of elevated levels of adenosine 3‘:5‘-monophosphate with a selective decrease in collagen productionQ40145940
An ultramicro method of amino acid analyses: Application to studies of protein metabolism in cultured cellsQ40442164
Idiopathic pulmonary fibrosis. Clinical, histologic, radiographic, physiologic, scintigraphic, cytologic, and biochemical aspectsQ40636848
Lymphokines: their role in lymphocyte responses. Properties of interleukin 1.Q40846747
Effect of cyclic AMP on the intracellular degradation of newly synthesized collagenQ41548210
The role of soluble factors in bleomycin-induced pulmonary fibrosisQ41891748
Prolyl-tRNA-based rates of protein and collagen synthesis in human lung fibroblastsQ42153425
Influence of asbestos fibers on collagen and prostaglandin production in fibroblast and macrophage co-culturesQ42469159
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectprostaglandin E2Q416554
pulmonary fibrosisQ32446
P304page(s)2082-2091
P577publication date1983-12-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleBleomycin-induced pulmonary fibrosis in hamsters. An alveolar macrophage product increases fibroblast prostaglandin E2 and cyclic adenosine monophosphate and suppresses fibroblast proliferation and collagen production
P478volume72

Reverse relations

cites work (P2860)
Q43926042Altered cytokine production in black patients with keloids
Q34545305Augmentation of fibroblast proliferation by bleomycin
Q41967080Bleomycin-stimulated hamster alveolar macrophages release interleukin-1.
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Q41908752Changes in distribution, morphology, and tumor necrosis factor-alpha secretion of alveolar macrophage subpopulations during the development of bleomycin-induced pulmonary fibrosis
Q41127857Development of acute lung injury after the combination of intravenous bleomycin and exposure to hyperoxia in rats
Q42861137Effects of Chinese herbal medicine Shenlong Decoction on mRNA expressions of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in lung tissue of rats with pulmonary fibrosis induced by bleomycin
Q34571998Effects of interferon-gamma on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts
Q67920824Exaggerated prostaglandin production by colonic smooth muscle in rabbit colitis
Q46195331Fibroblast proliferation induced by silica-exposed human alveolar macrophages
Q33916995Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis.
Q36350622Gamma interferon is the lymphokine and beta interferon the monokine responsible for inhibition of fibroblast collagen production and late but not early fibroblast proliferation
Q50232965Human alveolar macrophage and blood monocyte inhibition of fibroblast proliferation. Evidence for synergy between interleukin-1 and tumor necrosis factor
Q35836120Inhibition of bleomycin-induced pulmonary fibrosis by nordihydroguaiaretic acid. The role of alveolar macrophage activation and mediator production
Q36994346Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.
Q34623306Mechanism of enhanced fibroblast arachidonic acid metabolism by mononuclear cell factor
Q40372679Multiple facets of the modulation of growth by cAMP.
Q34563633Profiles of steady state levels of messenger RNAs coding for type I procollagen, elastin, and fibronectin in hamster lungs undergoing bleomycin-induced interstitial pulmonary fibrosis
Q41734846Proliferation of rat and human lung fibroblasts following exposure to prostaglandin E2.
Q46697034Prostacyclin agonist with thromboxane synthase inhibitory activity (ONO-1301) attenuates bleomycin-induced pulmonary fibrosis in mice
Q34192889Prostaglandins, thromboxanes and leukotrienes in clinical medicine
Q35831459Repeated exposures to enzyme-generated oxidants cause alveolitis, epithelial hyperplasia, and fibrosis in hamsters
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Q35816136The effects of bleomycin on alveolar macrophage growth factor secretion
Q50232974Tumor necrosis factor interacts with interleukin-1 and interferons to inhibit fibroblast proliferation via fibroblast prostaglandin-dependent and -independent mechanisms

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