Effects of ulinastatin and docetaxel on breast cancer invasion and expression of uPA, uPAR and ERK

scientific article published on July 29, 2011

Effects of ulinastatin and docetaxel on breast cancer invasion and expression of uPA, uPAR and ERK is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1014191638
P356DOI10.1186/1756-9966-30-71
P8608Fatcat IDrelease_g6biea7harglvlimrid62hhyaa
P953full work available at URLhttps://europepmc.org/articles/PMC3173354
https://europepmc.org/articles/PMC3173354?pdf=render
https://jeccr.biomedcentral.com/track/pdf/10.1186/1756-9966-30-71
https://link.springer.com/content/pdf/10.1186/1756-9966-30-71.pdf
P932PMC publication ID3173354
P698PubMed publication ID21798065
P5875ResearchGate publication ID51529498

P2093author name stringHong Wang
Jie Luo
Feng Gao
Xin Sun
Xiaoliang Zhao
Zhijun Sun
Biao Zhong
P2860cites workThe very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitroQ30303631
Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasionQ30304518
Binding of Urokinase-type Plasminogen Activator to Its Receptor in MCF-7 Cells Activates Extracellular Signal-regulated Kinase 1 and 2 Which Is Required for Increased Cellular MotilityQ30471919
Effects of ulinastatin and docataxel on breast tumor growth and expression of IL-6, IL-8, and TNF-αQ34633205
Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activityQ35749341
Effects of Ulinastatin and Cyclophosphamide on the Growth of Xenograft Breast Cancer and Expression of CXC Chemokine Receptor 4 and Matrix Metalloproteinase-9 in CancersQ39659055
Regulation of docetaxel-induced apoptosis of human melanoma cells by different isoforms of protein kinase C.Q40064543
AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclQ40093939
Sequence dependent exposure of mammary carcinoma cells to Taxotere and the MEK1/2 inhibitor U0126 causes enhanced cell killing in vitroQ40605102
Suppression of urokinase expression and invasiveness by urinary trypsin inhibitor is mediated through inhibition of protein kinase C- and MEK/ERK/c-Jun-dependent signaling pathwaysQ40846518
ERK signalling in metastatic human MDA-MB-231 breast carcinoma cells is adapted to obtain high urokinase expression and rapid cell proliferationQ40864626
Downstream targets of urokinase‐type plasminogen‐activator‐mediated signal transductionQ41027822
Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancyQ42256420
Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signalingQ42478267
Phosphatidylinositol 3-Kinase and NF-κB Regulate Motility of Invasive MDA-MB-231 Human Breast Cancer Cells by the Secretion of Urokinase-type Plasminogen ActivatorQ43786822
The Urokinase-type Plasminogen Activator Receptor Mediates Tyrosine Phosphorylation of Focal Adhesion Proteins and Activation of Mitogen-activated Protein Kinase in Cultured Endothelial CellsQ47859760
Elevated urokinase-specific surface receptor expression is maintained through its interaction with urokinase plasminogen activatorQ52575847
Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasivenessQ71171008
Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasisQ72769139
Induction of vascular SMC proliferation by urokinase indicates a novel mechanism of action in vasoproliferative disordersQ73965851
P407language of work or nameEnglishQ1860
P921main subjectdocetaxelQ420436
tumor invasionQ60750433
P304page(s)71
P577publication date2011-07-29
P1433published inJournal of Experimental & Clinical Cancer ResearchQ13739415
P1476titleEffects of ulinastatin and docetaxel on breast cancer invasion and expression of uPA, uPAR and ERK
P478volume30

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cites work (P2860)
Q53527300Consensus reference gene(s) for gene expression studies in human cancers: end of the tunnel visible?
Q39020785Synergism from the combination of ulinastatin and curcumin offers greater inhibition against colorectal cancer liver metastases via modulating matrix metalloproteinase-9 and E-cadherin expression
Q90681596The combination of ulinastatin and 5-fluorouracil synergistically inhibits hepatocellular carcinoma growth
Q38632598Ulinastatin - a newer potential therapeutic option for multiple organ dysfunction syndrome
Q48164348Ulinastatin decreases permeability of blood--brain barrier by inhibiting expression of MMP-9 and t-PA in postoperative aged rats
Q28545086Ulinastatin reduces the resistance of liver cancer cells to epirubicin by inhibiting autophagy

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