| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2006PNAS..10318603E |
| P356 | DOI | 10.1073/PNAS.0609157103 |
| P932 | PMC publication ID | 1693709 |
| P698 | PubMed publication ID | 17132737 |
| P5875 | ResearchGate publication ID | 6665409 |
| P50 | author | Veraragavan P. Eswarakumar | Q39807823 |
| P2093 | author name string | J Schlessinger | |
| D J Adams | |||
| C J Booth | |||
| J H Bae | |||
| F Ozcan | |||
| I Lax | |||
| F Tomé | |||
| E D Lew | |||
| P2860 | cites work | Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development. | Q52028262 |
| Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation | Q54246457 | ||
| Transforming growth factor beta s and fibroblast growth factors and their receptors: role in sutural biology and craniosynostosis | Q56381254 | ||
| Structural basis for FGF receptor dimerization and activation | Q22010544 | ||
| Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity | Q22254157 | ||
| Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization | Q24290400 | ||
| Cellular signaling by fibroblast growth factor receptors | Q24301087 | ||
| FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors | Q24554326 | ||
| Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways | Q24630500 | ||
| Structural basis of SNT PTB domain interactions with distinct neurotrophic receptors | Q27628653 | ||
| A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway | Q28240585 | ||
| Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction | Q28513556 | ||
| FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development | Q28585271 | ||
| The docking protein FRS2alpha is an essential component of multiple fibroblast growth factor responses during early mouse development | Q28592507 | ||
| Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras | Q28609649 | ||
| Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain | Q28609659 | ||
| Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia | Q29615030 | ||
| Progress toward understanding craniofacial malformations | Q30312672 | ||
| TGF-beta 1, TGF-beta 2, and TGF-beta 3 exhibit distinct patterns of expression during cranial suture formation and obliteration in vivo and in vitro. | Q30470194 | ||
| Clinical spectrum of fibroblast growth factor receptor mutations | Q33698671 | ||
| Craniosynostosis syndromes: from genes to premature fusion of skull bones | Q33754945 | ||
| Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain. | Q33889677 | ||
| The BMP antagonist noggin regulates cranial suture fusion | Q34189687 | ||
| Mechanisms underlying differential responses to FGF signaling | Q34415005 | ||
| Cranial skeletal biology. | Q35128228 | ||
| Fibroblast growth factor signaling in tumorigenesis | Q36111404 | ||
| A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis. | Q37493982 | ||
| Mutation associated with Crouzon syndrome causes ligand-independent dimerization and activation of FGF receptor-2. | Q42799258 | ||
| Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase | Q48022181 | ||
| P433 | issue | 49 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | craniosynostosis | Q378183 |
| P304 | page(s) | 18603-18608 | |
| P577 | publication date | 2006-11-28 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis | |
| P478 | volume | 103 |
| Q26999618 | 3-dimensional imaging modalities for phenotyping genetically engineered mice |
| Q26784240 | A Genetic-Pathophysiological Framework for Craniosynostosis |
| Q51419577 | Algorithm to assess cranial suture fusion with varying and discontinuous mineral density. |
| Q46199306 | Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis |
| Q93043734 | An FDA-Approved Drug Screen for Compounds Influencing Craniofacial Skeletal Development and Craniosynostosis |
| Q37644520 | Analysis of the Fgfr2C342Y mouse model shows condensation defects due to misregulation of Sox9 expression in prechondrocytic mesenchyme |
| Q36800176 | Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice |
| Q56262927 | Cancer drugs to treat birth defects |
| Q40206060 | Common skeletal features in rare diseases: New links between ciliopathies and FGF-related syndromes |
| Q42841259 | Craniosynostosis of coronal suture in twist1 mice occurs through endochondral ossification recapitulating the physiological closure of posterior frontal suture |
| Q42182046 | Craniosynostosis-associated Fgfr2(C342Y) mutant bone marrow stromal cells exhibit cell autonomous abnormalities in osteoblast differentiation and bone formation. |
| Q38026860 | Cross-talk between FGF and other cytokine signalling pathways during endochondral bone development |
| Q58693656 | Crouzon syndrome: Genetic and intervention review |
| Q93043741 | Current Approaches in the Development of Molecular and Pharmacological Therapies in Craniosynostosis Utilizing Animal Models |
| Q36918086 | Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma |
| Q37430764 | Deletion of Frs2alpha from the ureteric epithelium causes renal hypoplasia |
| Q91033620 | Developmental stage-specific role of Frs adapters as mediators of FGF receptor signaling in the oligodendrocyte lineage cells |
| Q47744494 | Dysregulated PDGFRα signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification |
| Q28293140 | Evidence that Fgf10 contributes to the skeletal and visceral defects of an Apert syndrome mouse model |
| Q47107716 | FGF-Dependent, Context-Driven Role for FRS Adapters in the Early Telencephalon. |
| Q37980181 | FGF/FGFR signaling in bone formation: progress and perspectives |
| Q37967808 | FGFs: Neurodevelopment's Jack-of-all-Trades - How Do They Do it? |
| Q47166239 | Fibroblast Growth Factor Receptor 2 (FGFR2) Mutation Related Syndromic Craniosynostosis |
| Q35181459 | Fibroblast growth factor receptor-Frs2α signaling is critical for nephron progenitors |
| Q26798215 | Fibroblast growth factor signaling in skeletal development and disease |
| Q38641260 | From Bench to Bedside and Back: Improving Diagnosis and Treatment of Craniofacial Malformations Utilizing Animal Models |
| Q33557690 | Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development |
| Q35468381 | Gene expression changes between patent and fused cranial sutures in a nonsyndromic craniosynostosis population |
| Q52795305 | Genetic advances in craniosynostosis. |
| Q28066570 | Genetic insights into the mechanisms of Fgf signaling |
| Q34632718 | Independent roles of Fgfr2 and Frs2alpha in ureteric epithelium |
| Q42625843 | MAPK/ERK Signaling Pathway Analysis in Primary Osteoblasts From Patients With Nonsyndromic Sagittal Craniosynostosis |
| Q28533662 | MicroRNA-17-92, a direct Ap-2α transcriptional target, modulates T-box factor activity in orofacial clefting |
| Q93043710 | Mouse Models of Syndromic Craniosynostosis |
| Q28088384 | New insights into craniofacial malformations |
| Q91081306 | Nonsyndromic craniosynostosis: novel coding variants |
| Q90943421 | Nuclear FGFR2 regulates musculoskeletal integration within the developing limb |
| Q38285398 | Osteoblast dysfunctions in bone diseases: from cellular and molecular mechanisms to therapeutic strategies |
| Q59793278 | Overexpression of causes craniofacial bone hypoplasia and ameliorates craniosynostosis in the Crouzon mouse |
| Q56262794 | Pure de novo partial trisomy 6p in a girl with craniosynostosis |
| Q37346972 | Quantification of shape and cell polarity reveals a novel mechanism underlying malformations resulting from related FGF mutations during facial morphogenesis |
| Q56333589 | RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis |
| Q98394726 | RUNX2-modifying enzymes: therapeutic targets for bone diseases |
| Q35755137 | Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models |
| Q38056686 | Role of FGFRL1 and other FGF signaling proteins in early kidney development |
| Q84196885 | Role of fibroblast growth factor receptor signaling in kidney development |
| Q33556357 | Role of fibroblast growth factor receptor signaling in kidney development |
| Q41815867 | Signal transducers and activators of transcription mediate fibroblast growth factor-induced vascular endothelial morphogenesis |
| Q28073737 | Signaling mechanisms implicated in cranial sutures pathophysiology: Craniosynostosis |
| Q54780420 | Skeletal analysis of the Fgfr3(P244R) mouse, a genetic model for the Muenke craniosynostosis syndrome. |
| Q47630825 | Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2. |
| Q38032781 | The Fgfr2 W290R mouse model of Crouzon syndrome |
| Q30563766 | The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data |
| Q38032780 | The role of vertebrate models in understanding craniosynostosis |
| Q37143936 | Tissue engineering in cleft palate and other congenital malformations. |
| Q35853292 | Ureteric morphogenesis requires Fgfr1 and Fgfr2/Frs2α signaling in the metanephric mesenchyme. |
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