Prostaglandin E2 release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation

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Prostaglandin E2 release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PNAS..10816104C
P356DOI10.1073/PNAS.1107533108
P932PMC publication ID3179065
P698PubMed publication ID21896757
P5875ResearchGate publication ID51624074

P50authorVincent PrevotQ42886402
P2093author name stringSergio R Ojeda
Gabriel Corfas
Pierre Poulain
Naresh K Hanchate
Jerome Clasadonte
P2860cites workSelectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenaseQ24563699
Astrocytes control breathing through pH-dependent release of ATPQ24612975
Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acidQ24657423
Induction of PGE2 by estradiol mediates developmental masculinization of sex behaviorQ28168712
International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypesQ28239501
Glia-derived D-serine controls NMDA receptor activity and synaptic memoryQ28241395
The mystery and magic of glia: a perspective on their roles in health and diseaseQ28300305
Neuron-to-glia signaling mediated by excitatory amino acid receptors regulates ErbB receptor function in astroglial cells of the neuroendocrine brainQ28582971
Mechanisms underlying episodic gonadotropin-releasing hormone secretionQ30310866
Retrograde endocannabinoid signaling reduces GABAergic synaptic transmission to gonadotropin-releasing hormone neurons.Q30415677
The neurobiology of preovulatory and estradiol-induced gonadotropin-releasing hormone surgesQ30426533
Glucosensing by GnRH neurons: inhibition by androgens and involvement of AMP-activated protein kinaseQ30427162
Diurnal and estradiol-dependent changes in gonadotropin-releasing hormone neuron firing activityQ30438409
Astroglia in medullary dorsal horn (trigeminal spinal subnucleus caudalis) are involved in trigeminal neuropathic pain mechanismsQ33582175
Long-term potentiation depends on release of D-serine from astrocytesQ33595366
Gliotransmission: Exocytotic release from astrocytesQ33823638
Involvement of transforming growth factor alpha in the release of luteinizing hormone-releasing hormone from the developing female hypothalamusQ33924904
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivoQ33985913
Timing and completion of puberty in female mice depend on estrogen receptor alpha-signaling in kisspeptin neuronsQ34450182
Characterization of Kiss1 neurons using transgenic mouse modelsQ34518585
The origins and significance of pulsatility in hormone secretion from the pituitaryQ35860716
Astrocyte control of synaptic transmission and neurovascular coupling.Q36525563
Cyclooxygenase-2 in synaptic signalingQ36922736
Glial regulation of the cerebral microvasculatureQ36983682
Activity-dependent structural and functional plasticity of astrocyte-neuron interactions.Q37216071
Function-related structural plasticity of the GnRH system: a role for neuronal-glial-endothelial interactionsQ37764978
Developmental profile and properties of sulforhodamine 101--Labeled glial cells in acute brain slices of rat hippocampusQ40135368
Glutamate‐mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytesQ40633084
Effect of Inhibitors of Prostaglandin Synthesis on Gonadotropin Release in the Rat1Q41072980
Estradiol enhances prostaglandin E2 receptor gene expression in luteinizing hormone-releasing hormone (LHRH) neurons and facilitates the LHRH response to PGE2 by activating a glia-to-neuron signaling pathwayQ41075616
Function-related plasticity in hypothalamusQ41369783
Use of fluorocitrate and fluoroacetate in the study of brain metabolismQ41595198
Excitatory amino acids: evidence for a role in the control of reproduction and anterior pituitary hormone secretionQ41613399
Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep lossQ41776277
Astrocyte-mediated distributed plasticity at hypothalamic glutamate synapsesQ42025298
Endothelins stimulate expression of cyclooxygenase 2 in rat cultured astrocytesQ42476710
ATP-sensitive potassium channel-mediated lactate effect on orexin neurons: implications for brain energetics during arousal.Q43016902
Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation.Q44240672
Normal female sexual development requires neuregulin-erbB receptor signaling in hypothalamic astrocytes.Q44270207
erbB-1 and erbB-4 receptors act in concert to facilitate female sexual development and mature reproductive function.Q45182770
Kisspeptin depolarizes gonadotropin-releasing hormone neurons through activation of TRPC-like cationic channels.Q46628485
Postsynaptically synthesized prostaglandin E2 (PGE2) modulates hippocampal synaptic transmission via a presynaptic PGE2 EP2 receptor.Q46776139
Activation of neuronal nitric oxide release inhibits spontaneous firing in adult gonadotropin-releasing hormone neurons: a possible local synchronizing signalQ46897695
Transforming growth factor beta1 regulates the expression of cyclooxygenase in cultured cortical astrocytes and neurons.Q47777972
Stimulation of cyclic adenosine 3',5'-monophosphate production enhances hypothalamic luteinizing hormone-releasing hormone release without increasing prostaglandin E2 synthesis: studies in prepubertal female ratsQ48460639
Prostaglandin E2-induced luteinizing hormone-releasing hormone release involves mobilization of intracellular Ca+2.Q48494415
Expression of mRNAs encoding receptors that mediate stress signals in gonadotropin-releasing hormone neurons of the mouseQ48524764
Prostaglandins stimulate calcium-dependent glutamate release in astrocytes.Q48556921
Notch1 signaling regulates radial glia differentiation through multiple transcriptional mechanisms.Q48608285
Hypothalamic astrocytes respond to transforming growth factor-alpha with the secretion of neuroactive substances that stimulate the release of luteinizing hormone-releasing hormoneQ48825057
Neuregulins signaling via a glial erbB-2-erbB-4 receptor complex contribute to the neuroendocrine control of mammalian sexual development.Q52173234
A role for N-methyl-D-aspartate (NMDA) receptors in the control of LH secretion and initiation of female puberty.Q53702277
Glia-to-neuron signaling and the neuroendocrine control of female pubertyQ58260812
GABA- and glutamate-activated channels in green fluorescent protein-tagged gonadotropin-releasing hormone neurons in transgenic miceQ74582901
P433issue38
P407language of work or nameEnglishQ1860
P921main subjectprostaglandin E2Q416554
astrocyteQ502961
P304page(s)16104-16109
P577publication date2011-09-06
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleProstaglandin E2 release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation
P478volume108

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cites work (P2860)
Q37600716A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primates
Q63976668Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in mice
Q94464568Acupuncture Improving Early Sexual Development of Girls with Peripheral Precocious Puberty: A Prospective Cohort Study
Q53087310Astrocyte-Specific Deletion of Peroxisome-Proliferator Activated Receptor-γ Impairs Glucose Metabolism and Estrous Cycling in Female Mice.
Q38193649Central genomic regulation of the expression of oestrous behaviour in dairy cows: a review
Q38839109Control of puberty onset and fertility by gonadotropin-releasing hormone neurons
Q38959910Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish.
Q47151210Downregulation of Deiodinase 3 is the earliest event in photoperiodic and photorefractory activation of the gonadotropic axis in seasonal hamsters
Q92702894Effect of Inflammation on Female Gonadotropin-Releasing Hormone (GnRH) Neurons: Mechanisms and Consequences
Q36594940Eicosanoids Derived From Arachidonic Acid and Their Family Prostaglandins and Cyclooxygenase in Psychiatric Disorders
Q64094016Electro-Acupuncture Affects the Activity of the Hypothalamic-Pituitary-Ovary Axis in Female Rats
Q36594102Epidural methadone results in dose-dependent analgesia in cancer pain, further enhanced by epidural dexamethasone
Q38244664Epigenetic regulation of female puberty.
Q93370017ErbB4 point mutation in CU3 inbred rats affects gonadotropin-releasing-hormone neuronal function via compromised neuregulin-stimulated prostaglandin E2 release from astrocytes
Q90042573Genome-wide effects of social status on DNA methylation in the brain of a cichlid fish, Astatotilapia burtoni
Q35971394Gliotransmission by prostaglandin e(2): a prerequisite for GnRH neuronal function?
Q52362092Hypothalamic Epigenetics Driving Female Puberty.
Q36689827Manganese protects against the effects of alcohol on hypothalamic puberty-related hormones
Q48112946Microglia control the glycinergic but not the GABAergic synapses via prostaglandin E2 in the spinal cord.
Q64889645Modulation of Gonadotropin-Releasing Hormone Neuron Activity and Secretion in Mice by Non-peptide Neurotransmitters, Gasotransmitters, and Gliotransmitters.
Q26826892Neuroestrogen, rapid action of estradiol, and GnRH neurons
Q40152299Participation of hypothalamic CB1 receptors in reproductive axis disruption during immune challenge
Q36745134Prostaglandin E2, a postulated astrocyte-derived neurovascular coupling agent, constricts rather than dilates parenchymal arterioles.
Q35767260Sexual differentiation of the rodent brain: dogma and beyond
Q47705880The special relationship: glia-neuron interactions in the neuroendocrine hypothalamus
Q41810210Voluntary Exercise Induces Astrocytic Structural Plasticity in the Globus Pallidus
Q53677064[Role of tanycytes within the blood-hypothalamus interface].

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