Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp)

scientific article published on January 1, 2011

Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp) is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JBMR.202
P953full work available at URLhttps://europepmc.org/articles/pmc3179315?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20687161/?tool=EBI
https://academic.oup.com/jbmr/article-pdf/26/1/220/56559938/202_ftp.pdf
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjbmr.202
https://europepmc.org/articles/PMC3179315
https://europepmc.org/articles/PMC3179315?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20687161/pdf/?tool=EBI
P932PMC publication ID3179315
P698PubMed publication ID20687161
P5875ResearchGate publication ID45506561

P50authorJames P SimmerQ91794735
P2093author name stringYasuo Yamakoshi
Jan C-C Hu
Shuhei Tsuchiya
Fumiko Yamakoshi
Amelia S. Richardson
P2860cites workDentin phosphoprotein and dentin sialoprotein are cleavage products expressed from a single transcript coded by a gene on human chromosome 4. Dentin phosphoprotein DNA sequence determinationQ24312880
Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1Q24318740
The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenic protein-1Q24599618
Meprins, membrane-bound and secreted astacin metalloproteinasesQ24646365
Bone morphogenetic protein-1: the type I procollagen C-proteinaseQ28115746
DSPP mutation in dentinogenesis imperfecta Shields type IIQ28200045
The expression of dentin sialophosphoprotein gene in boneQ28208862
Bone morphogenetic protein-1/Tolloid-like proteinases process dentin matrix protein-1Q28212436
Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloidQ28586602
Identification and characterization of the carboxyl-terminal region of rat dentin sialoproteinQ31478707
The evolution of the vertebrate metzincins; insights from Ciona intestinalis and Danio rerioQ33282314
Tissue-specific expression of dentin sialophosphoprotein (DSPP) and its polymorphisms in mouse tissuesQ33446942
A proposed classification for heritable human dentine defects with a description of a new entityQ34699098
Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinasesQ35150332
Disorders of human dentinQ36197243
Cloning and sequence determination of rat dentin sialoprotein, a novel dentin proteinQ36742074
Hereditary dentin defectsQ36798995
The bone morphogenetic protein 1/Tolloid-like metalloproteinasesQ36846125
Overlapping DSPP mutations cause dentin dysplasia and dentinogenesis imperfectaQ37000972
Porcine dentin sialophosphoprotein: length polymorphisms, glycosylation, phosphorylation, and stabilityQ37146131
Dentin sialoprotein and dentin phosphoprotein have distinct roles in dentin mineralizationQ37379252
Dentin glycoprotein: the protein in the middle of the dentin sialophosphoprotein chimeraQ38330183
Porcine dentin sialoprotein is a proteoglycan with glycosaminoglycan chains containing chondroitin 6-sulfateQ38334422
Mutational hot spot in the DSPP gene causing dentinogenesis imperfecta type II.Q38515714
Dentin matrix proteins: composition and possible functions in calcificationQ38686252
Key proteolytic cleavage site and full-length form of DSPPQ39723911
Dentin sialophosphoprotein (DSPP) is cleaved into its two natural dentin matrix products by three isoforms of bone morphogenetic protein-1 (BMP1).Q40307101
A comprehensive analysis of normal variation and disease-causing mutations in the human DSPP geneQ41172686
Mmp-20 and Klk4 cleavage site preferences for amelogenin sequencesQ42566135
Sequence determination of an extremely acidic rat dentin phosphoproteinQ42634149
Novel COL1A1 mutation (G559C) [correction of G599C] associated with mild osteogenesis imperfecta and dentinogenesis imperfectaQ43564734
Mutation of the signal peptide region of the bicistronic gene DSPP affects translocation to the endoplasmic reticulum and results in defective dentine biomineralizationQ44159131
Dentin phosphoprotein frameshift mutations in hereditary dentin disorders and their variation patterns in normal human population.Q45400197
Determination of matrix metalloproteinases in human radicular dentin.Q46028114
Dentin sialophosphoprotein knockout mouse teeth display widened predentin zone and develop defective dentin mineralization similar to human dentinogenesis imperfecta type III.Q46287190
Amelogenin gene expression in porcine odontoblastsQ46288547
Noncollagenous proteins of dentin. A re-examination of proteins from rat incisor dentin utilizing techniques to avoid artifacts.Q50943457
Dentin sialophosphoprotein is processed by MMP-2 and MMP-20 in vitro and in vivo.Q52004411
Matrix metalloproteinase-8 (MMP-8) is the major collagenase in human dentin.Q53593290
Evaluation of oral problems in an osteogenesis imperfecta population.Q53936450
Expression profile of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in mature human odontoblasts and pulp tissue.Q54783300
Isoelectric focusing of the phosphoprotein of rat-incisor dentin in ampholine and acid pH gradients. Evidence for carrier ampholyte-protein complexesQ66705902
Isolation, characterization and immunolocalization of a 53-kDal dentin sialoprotein (DSP)Q67989523
Characterization and identification of a human dentin phosphophorynQ71226748
Dynamic processing of recombinant dentin sialoprotein-phosphophoryn proteinQ80796179
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)220-228
P577publication date2011-01-01
P1433published inJournal of Bone and Mineral ResearchQ15750941
P1476titleAstacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp)
P478volume26

Reverse relations

cites work (P2860)
Q34513400Adhesive and migratory effects of phosphophoryn are modulated by flanking peptides of the integrin binding motif
Q52945677CCN2/CTGF expression via cellular uptake of BMP-1 is associated with reparative dentinogenesis.
Q33936594DPP and DSP are Necessary for Maintaining TGF-β1 Activity in Dentin
Q34345686DSP-PP precursor protein cleavage by tolloid-related-1 protein and by bone morphogenetic protein-1
Q37491982DSPP contains an IRES element responsible for the translation of dentin phosphophoryn.
Q51164249Deficiency of the DSPP-cleaving enzymes meprin α and meprin β does not result in dentin malformation in mice.
Q52945167Dentin Sialophosphoprotein-derived Proteins in the Dental Pulp.
Q36453278Dentin sialophosphoprotein and dentin matrix protein-1: Two highly phosphorylated proteins in mineralized tissues
Q35697998Enamel malformations associated with a defined dentin sialophosphoprotein mutation in two families.
Q50223977Essential Roles of Bone Morphogenetic Protein-1 and Mammalian Tolloid-like 1 in Postnatal Root Dentin Formation
Q92542941Extracellular Matrix Composition and Remodeling: Current Perspectives on Secondary Palate Formation, Cleft Lip/Palate, and Palatal Reconstruction
Q44536963Human serine protease HTRA1 positively regulates osteogenesis of human bone marrow-derived mesenchymal stem cells and mineralization of differentiating bone-forming cells through the modulation of extracellular matrix protein.
Q34905394Immunocytochemical detection of dentin matrix proteins in primary teeth from patients with dentinogenesis imperfecta associated with osteogenesis imperfecta
Q48130931Inactivation of bone morphogenetic protein 1 (Bmp1) and tolloid-like 1 (Tll1) in cells expressing type I collagen leads to dental and periodontal defects in mice.
Q34473760Overexpressing the NH2-terminal fragment of dentin sialophosphoprotein (DSPP) aggravates the periodontal defects in Dspp knockout mice
Q36911912Partial blocking of mouse DSPP processing by substitution of Gly(451)-Asp(452) bond suggests the presence of secondary cleavage site(s)
Q33811338Porcine dentin sialoprotein glycosylation and glycosaminoglycan attachments
Q33707712Premature primary tooth eruption in cognitive/motor-delayed ADNP-mutated children
Q35264713Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates
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Q36707613Transgenic expression of dentin phosphoprotein inhibits skeletal development

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