Human cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription

scientific article

Human cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1371/JOURNAL.PPAT.1004350
P8608Fatcat IDrelease_j43t4bpolzhqxizjejyhafkyym
P932PMC publication ID4148446
P698PubMed publication ID25166009
P5875ResearchGate publication ID265135154

P50authorDeborah J. LenschowQ85543822
P2093author name stringDong Yu
Jessica A Campbell
Yi-Chieh Perng
P2860cites workAssociation of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzymeQ24537648
A protein phosphatase functions to recycle RNA polymerase IIQ24602725
Consensus on the role of human cytomegalovirus in glioblastomaQ24632103
Simple and highly efficient BAC recombineering using galK selectionQ24794075
Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cureQ26999858
Uniform transitions of the general RNA polymerase II transcription complexQ27931804
Ssu72 Is an RNA polymerase II CTD phosphataseQ27936648
Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinaseQ29614789
Identification of Herpes TATT-binding protein.Q30360795
Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivoQ31063997
Molecular and functional analysis of the virus- and interferon-inducible human MxA promoterQ33261592
Ctk1 promotes dissociation of basal transcription factors from elongating RNA polymerase IIQ33285680
Viral DNA synthesis-dependent titration of a cellular repressor activates transcription of the human adenovirus type 2 IVa2 geneQ33581711
Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutantQ33782001
Identification of positive and negative regulatory regions involved in regulating expression of the human cytomegalovirus UL94 late promoter: role of IE2-86 and cellular p53 in mediating negative regulatory function.Q33782285
Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γQ33886711
Simian virus 40 late gene expression is regulated by members of the steroid/thyroid hormone receptor superfamilyQ33911682
Optimized nanosecond pulsed electric field therapy can cause murine malignant melanomas to self-destruct with a single treatmentQ34057997
CDK8 is a positive regulator of transcriptional elongation within the serum response networkQ34094495
Human cytomegalovirus infection induces specific hyperphosphorylation of the carboxyl-terminal domain of the large subunit of RNA polymerase II that is associated with changes in the abundance, activity, and localization of cdk9 and cdk7.Q34228694
Do pathogens accelerate atherosclerosis?Q34389205
ICP27 interacts with the C-terminal domain of RNA polymerase II and facilitates its recruitment to herpes simplex virus 1 transcription sites, where it undergoes proteasomal degradation during infectionQ34545620
The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomesQ34566036
Hyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediatorQ34610960
Elongin B-mediated epigenetic alteration of viral chromatin correlates with efficient human cytomegalovirus gene expression and replicationQ34713776
Molecular evolution of the RNA polymerase II CTD.Q34778014
Control of the papillomavirus early-to-late switch by differentially expressed SRp20Q34863597
Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL/IRL13 geneQ34971048
Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expressionQ34998851
Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcriptionQ35036881
The human cytomegalovirus gene products essential for late viral gene expression assemble into prereplication complexes before viral DNA replicationQ35077548
ORF18 is a transfactor that is essential for late gene transcription of a gammaherpesvirusQ35101383
Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic targetQ35370135
High-resolution human cytomegalovirus transcriptomeQ35621344
Fast transcription rates of RNA polymerase II in human cellsQ35632803
Human cytomegalovirus UL38 protein blocks apoptosisQ35785145
Herpes simplex virus immediate-early protein ICP22 triggers loss of serine 2-phosphorylated RNA polymerase IIQ35857527
The Epstein-Barr virus BcRF1 gene product is a TBP-like protein with an essential role in late gene expression.Q36023187
Sites and roles of phosphorylation of the human cytomegalovirus DNA polymerase subunit UL44.Q36212341
Histone H3 lysine 4 methylation marks postreplicative human cytomegalovirus chromatin.Q36246288
Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigenQ36266183
Map position and nucleotide sequence of the gene for the large structural phosphoprotein of human cytomegalovirusQ36426771
Potential role for herpes simplex virus ICP8 DNA replication protein in stimulation of late gene expressionQ36689135
A transcription reinitiation intermediate that is stabilized by activatorQ59071495
Cytomegalovirus infection is associated with cardiac allograft rejection and atherosclerosisQ69349578
Activation of the SV40 late promoter: direct effects of T antigen in the absence of viral DNA replicationQ70183910
Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomyQ71210092
Potential role of human cytomegalovirus and p53 interaction in coronary restenosisQ72041267
Nuclear run-on assay using biotin labeling, magnetic bead capture and analysis by fluorescence-based RT-PCRQ73206333
A universal RNA polymerase II CTD cycle is orchestrated by complex interplays between kinase, phosphatase, and isomerase enzymes along genesQ83344227
A PY-nuclear localization signal is required for nuclear accumulation of HCMV UL79 proteinQ84213794
Regulation of cytomegalovirus late-gene expression: differential use of three start sites in the transcriptional activation of ICP36 gene expressionQ36792122
Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.Q36803871
Role of cdk9 in the optimization of expression of the genes regulated by ICP22 of herpes simplex virus 1Q36949638
Immunobiology of human cytomegalovirus: from bench to bedside.Q37050965
ORF30 and ORF34 are essential for expression of late genes in murine gammaherpesvirus 68.Q37099697
Murine cytomegalovirus protein pM79 is a key regulator for viral late transcriptionQ37123370
Functional roles of the human cytomegalovirus essential IE86 proteinQ37219975
Cyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus productionQ37567845
Sequence of protein synthesis in cells infected by human cytomegalovirus: early and late virus-induced polypeptidesQ37601559
The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complexQ37617641
"Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactionsQ37620941
Cytomegalovirus seropositivity and C-reactive protein have independent and combined predictive value for mortality in patients with angiographically demonstrated coronary artery diseaseQ37875480
Infectious causes of atherosclerosisQ37879248
Is human cytomegalovirus a target in cancer therapy?Q37975925
Congenital cytomegalovirus infection: current strategies and future perspectives.Q38041178
SV40 early-to-late switch involves titration of cellular transcriptional repressorsQ38314769
Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication.Q38348043
Significant association of multiple human cytomegalovirus genomic Loci with glioblastoma multiforme samplesQ38407022
Adenovirus E1A recruits the human Paf1 complex to enhance transcriptional elongationQ39018186
Analysis of the interactions of viral and cellular factors with human cytomegalovirus lytic origin of replication, oriLytQ39413787
The human cytomegalovirus gene UL79 is required for the accumulation of late viral transcripts.Q39582938
The initiator element in a herpes simplex virus type 1 late-gene promoter enhances activation by ICP4, resulting in abundant late-gene expressionQ39682517
Adenovirus late-phase infection is controlled by a novel L4 promoter.Q39707314
Identification of cis sequences required for lytic DNA replication and packaging of murine gammaherpesvirus 68.Q39754873
Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84.Q39848912
Analysis of the functions of herpes simplex virus type 1 regulatory protein ICP0 that are critical for lytic infection and derepression of quiescent viral genomesQ39876579
Translational regulation of the human cytomegalovirus pp28 (UL99) late geneQ39878014
Temporal dynamics of cytomegalovirus chromatin assembly in productively infected human cellsQ39940813
Interaction of the viral activator protein ICP4 with TFIID through TAF250.Q40019074
Murine gammaherpesvirus 68 open reading frame 24 is required for late gene expression after DNA replicationQ40152967
The control of herpes simplex virus type-1 late gene transcription: a 'TATA-box'/cap site region is sufficient for fully efficient regulated activityQ40419273
Lytic cycle gene regulation of Epstein-Barr virusQ40487977
Phosphorylation of the RNA polymerase II carboxyl-terminal domain in human cytomegalovirus-infected cells and in vitro by the viral UL97 protein kinaseQ40548350
Murine gammaherpesvirus 68 open reading frame 31 is required for viral replicationQ40551523
Activation of the early-late switch in adenovirus type 5 major late transcription unit expression by L4 gene products.Q40594994
Cytomegalovirus and atherosclerosisQ40726892
The basics of basal transcription by RNA polymerase II.Q40739619
Human cytomegalovirus: bacterial artificial chromosome (BAC) cloning and genetic manipulationQ40899325
Proteasome subunits relocalize during human cytomegalovirus infection, and proteasome activity is necessary for efficient viral gene transcriptionQ41905953
Murine cytomegalovirus protein pM92 is a conserved regulator of viral late gene expressionQ41909097
Cytomegalovirus UL91 is essential for transcription of viral true late (γ2) genesQ43079584
Nuclear run-on assayQ43164887
Importance of cytomegalovirus viraemia in risk of disease progression and death in HIV-infected patients receiving highly active antiretroviral therapyQ43564797
Characterization of the human cytomegalovirus UL75 (glycoprotein H) late gene promoterQ43717763
Activation of herpes simplex virus 1 gamma 2 genes by viral DNA replicationQ45842282
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P921main subjectCytomegalovirusQ6946
P304page(s)e1004350
P577publication date2014-08-28
P1433published inPLOS PathogensQ283209
P1476titleHuman cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription
P478volume10